| 708472 | Asmt | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity; identical protein binding (ortholog); INVOLVED IN melatonin biosynthetic process; negative regulation of male gonad development (ortholog); PARTICIPATES IN methion ine cycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog); INTERACTS WITH acetamide; acrylamide; ammonium chloride | 12 | 21418477 | 21423336 | Rat | 54 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1353638 | ASMT | acetylserotonin O-methyltransferase | This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively splice d transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010] | X | 1615059 | 1643081 | Human | 54 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1353638 | ASMT | acetylserotonin O-methyltransferase | This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively splice d transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010] | Y | 1615059 | 1643081 | Human | 54 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 3731974 | Asmt | acetylserotonin O-methyltransferase | This gene belongs to the methyltransferase superfamily and is located in the pseudoautosomal region (PAR) of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin and is abundant in the pineal gland. Two amino acid substitutions (R78G and R242C) are p resent in the encoded protein derived from the reference strain, C57BL/6J, and this protein shows low enzyme activity relative to the protein derived from other strains. [provided by RefSeq, May 2015] | X | 169106379 | 169111787 | Mouse | 58 | symbol , old_gene_name , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8707822 | Asmt | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES I N methionine cycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog) | NW_004955499 | 1131637 | 1151861 | Chinchilla | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11721182 | ASMT | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); S-adenosylmethionine-dependent methyltransferase activity (ortholog); INVOLVED IN melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES IN methionine c ycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog) | | | | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12373008 | ASMT | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); S-adenosylmethionine-dependent methyltransferase activity (ortholog); INVOLVED IN melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES IN methionine c ycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog) | X | 1012952 | 1025684 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12490190 | Asmt | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES I N methionine cycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog) | NW_004936644 | 3707365 | 3708601 | Squirrel | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18480358 | ASMT | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES I N methionine cycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog) | | | | Green Monkey | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18903722 | Asmt | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES I N methionine cycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253520 | asmt | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625934127 | Asmt | acetylserotonin O-methyltransferase | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN melatonin biosynthetic process (ortholog); negative regulation of male gonad development (ortholog); PARTICIPATES I N methionine cycle/metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH autistic disorder (ortholog); Wilson disease (ortholog) | | | | Black Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155254480 | asmt.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596933832 | asmt.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934215 | asmt.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596935316 | asmt.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596935987 | asmt.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155253519 | asmt.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7365766 | BORCS7-ASMT | BORCS7-ASMT readthrough (NMD candidate) | This locus represents naturally occurring read-through transcription between the neighboring C10orf32 (chromosome 10 open reading frame 32) and AS3MT (arsenic, +3 oxidation state, methyltransferase) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is ther efore unlikely to produce a protein product. [provided by RefSeq, Dec 2010] | 10 | 102854210 | 102901899 | Human | 7 | symbol , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 1306877 | Asmtl | acetylserotonin O-methyltransferase-like | ENCODES a protein that exhibits hydrolase activity (inferred); nucleoside triphosphate diphosphatase activity (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; amphetamine; bis(2-ethylhexyl) ph thalate | 12 | 21429119 | 21431847 | Rat | 67 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1315744 | ASMTL | acetylserotonin O-methyltransferase like | The protein encoded by this gene has an N-terminus that is similar to the multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli, while the C-terminus is similar to N-acetylserotonin O-methyltransferase. This gene is located in the pseudoautosomal regio n 1 (PAR1) of X and Y chromosomes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] | X | 1403139 | 1453756 | Human | 80 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1315744 | ASMTL | acetylserotonin O-methyltransferase like | The protein encoded by this gene has an N-terminus that is similar to the multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli, while the C-terminus is similar to N-acetylserotonin O-methyltransferase. This gene is located in the pseudoautosomal regio n 1 (PAR1) of X and Y chromosomes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] | Y | 1403139 | 1453756 | Human | 80 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 9027552 | Asmtl | acetylserotonin O-methyltransferase like | ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (ortholog) | NW_004955499 | 1033926 | 1047018 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11693462 | ASMTL | acetylserotonin O-methyltransferase like | ENCODES a protein that exhibits hydrolase activity (inferred); methyltransferase activity (inferred); nucleoside triphosphate diphosphatase activity (inferred); INVOLVED IN methylation (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (inferre d) | | | | Bonobo | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12285915 | ASMTL | acetylserotonin O-methyltransferase like | ENCODES a protein that exhibits hydrolase activity (inferred); methyltransferase activity (inferred); nucleoside triphosphate diphosphatase activity (inferred); INVOLVED IN methylation (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (inferre d) | X | 1102094 | 1118791 | Dog | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12575638 | Asmtl | acetylserotonin O-methyltransferase like | ENCODES a protein that exhibits hydrolase activity (inferred); methyltransferase activity (inferred); nucleoside triphosphate diphosphatase activity (inferred); INVOLVED IN methylation (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (ortholo g) | NW_004936644 | 3775940 | 3789377 | Squirrel | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14278372 | ASMTL | acetylserotonin O-methyltransferase like | ENCODES a protein that exhibits hydrolase activity (inferred); methyltransferase activity (inferred); nucleoside triphosphate diphosphatase activity (inferred); INVOLVED IN methylation (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (inferre d) | | | | Pig | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18753748 | ASMTL | acetylserotonin O-methyltransferase like | ENCODES a protein that exhibits acetylserotonin O-methyltransferase activity (inferred); hydrolase activity (inferred); methyltransferase activity (inferred); INVOLVED IN melatonin biosynthetic process (inferred); methylation (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepitheli oma (ortholog); FOUND IN cytosol (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18904290 | Asmtl | acetylserotonin O-methyltransferase like | ENCODES a protein that exhibits hydrolase activity (inferred); methyltransferase activity (inferred); nucleoside triphosphate diphosphatase activity (inferred); INVOLVED IN methylation (inferred); ASSOCIATED WITH acute myeloid leukemia (ortholog); myoepithelioma (ortholog); FOUND IN cytosol (ortholo g) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239510 | asmtl | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155247212 | asmtl.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1345758 | ASMTL-AS1 | ASMTL antisense RNA 1 | This gene serves as the antisense to the acetylserotonin O-methyltransferase-like gene. Multiple non-coding transcript variants have been found for this gene. [provided by RefSeq, Oct 2011] | X | 1400531 | 1415421 | Human | 11 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 1345758 | ASMTL-AS1 | ASMTL antisense RNA 1 | This gene serves as the antisense to the acetylserotonin O-methyltransferase-like gene. Multiple non-coding transcript variants have been found for this gene. [provided by RefSeq, Oct 2011] | Y | 1400531 | 1415421 | Human | 11 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |
| 1612743 | 2510022D24Rik | RIKEN cDNA 2510022D24 gene | | X | 169090871 | 169098529 | Mouse | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
