| 1311927 | Anapc7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); brain development (ortholog); protein branched polyubiquitination (ortholog); PARTICIPATES IN cell cycl e pathway, mitotic; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH FERGUSON-BONNI NEURODEVELOPMENTAL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (ortholog); heterochromatin (ortholog); intercellular bridge (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 12 | 39793518 | 39821614 | Rat | 101 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1323638 | Anapc7 | anaphase promoting complex subunit 7 | Predicted to enable enzyme-substrate adaptor activity and protein phosphatase binding activity. Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein polyubiquitinatio n. Predicted to be located in heterochromatin; nucleus; and spindle. Predicted to be part of anaphase-promoting complex. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study syndromic intellectual disability. Orthologous to human ANAPC7 (anaphase promoting complex subunit 7). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 122559646 | 122582978 | Mouse | 140 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1344930 | ANAPC7 | anaphase promoting complex subunit 7 | This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation throug h ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] | 12 | 110372900 | 110403708 | Human | 117 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8940434 | Anapc7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); brain development (ortholog); protein branched polyubiquitination (ortholog); ASSOCIATED WITH FERGUSON- BONNI NEURODEVELOPMENTAL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (ortholog); heterochromatin (ortholog); intercellular bridge (ortholog) | NW_004955482 | 7302853 | 7328145 | Chinchilla | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11743366 | ANAPC7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); protein phosphatase binding (inferred); INVOLVED IN anaphase-promoting complex-dependent catabolic process (inferred); brain development (inferred); cell division (inferred); ASSOCIATED WITH FERGUSON-BONNI NEURODEVELOPMENT AL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (inferred); heterochromatin (inferred); intercellular bridge (inferred) | 12 | 107946756 | 107977489 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12275454 | ANAPC7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); protein phosphatase binding (inferred); INVOLVED IN anaphase-promoting complex-dependent catabolic process (inferred); brain development (inferred); cell division (inferred); ASSOCIATED WITH FERGUSON-BONNI NEURODEVELOPMENT AL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (inferred); heterochromatin (inferred); intercellular bridge (inferred) | 26 | 8223627 | 8247976 | Dog | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12724265 | Anapc7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); protein phosphatase binding (inferred); INVOLVED IN anaphase-promoting complex-dependent catabolic process (inferred); brain development (inferred); cell division (inferred); ASSOCIATED WITH FERGUSON-BONNI NEURODEVELOPMENT AL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (inferred); heterochromatin (inferred); intercellular bridge (inferred) | NW_004936558 | 3365729 | 3391292 | Squirrel | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625896154 | Anapc7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); brain development (ortholog); protein branched polyubiquitination (ortholog); ASSOCIATED WITH FERGUSON- BONNI NEURODEVELOPMENTAL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (ortholog); heterochromatin (ortholog); intercellular bridge (ortholog) | | | | Black Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234290 | anapc7 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 20865850 | ANAPC7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); protein phosphatase binding (inferred); INVOLVED IN anaphase-promoting complex-dependent catabolic process (inferred); brain development (inferred); cell division (inferred); FOUND IN anaphase-promoting complex (inferred); heterochromatin (inferred); intercellular bridge (inferred) | | | | Green Monkey | 19 | symbol | gene, protein-coding |
| 18388035 | ANAPC7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); brain development (ortholog); protein branched polyubiquitination (ortholog); ASSOCIATED WITH FERGUSON- BONNI NEURODEVELOPMENTAL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (ortholog); heterochromatin (ortholog); intercellular bridge (ortholog) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13897465 | ANAPC7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); protein phosphatase binding (inferred); INVOLVED IN anaphase-promoting complex-dependent catabolic process (inferred); brain development (inferred); cell division (inferred); ASSOCIATED WITH FERGUSON-BONNI NEURODEVELOPMENT AL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (inferred); heterochromatin (inferred); intercellular bridge (inferred) | | | | Pig | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915539 | Anapc7 | anaphase promoting complex subunit 7 | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); protein phosphatase binding (ortholog); INVOLVED IN anaphase-promoting complex-dependent catabolic process (ortholog); brain development (ortholog); protein branched polyubiquitination (ortholog); ASSOCIATED WITH FERGUSON- BONNI NEURODEVELOPMENTAL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN heterochromatin (ortholog); intercellular bridge (ortholog); microtubule cytoskeleton (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234289 | anapc7.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155242587 | anapc7.S | | | | | | African Clawed Frog | | symbol | gene, null |