ANAPC7 (anaphase promoting complex subunit 7) - Rat Genome Database

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Gene: ANAPC7 (anaphase promoting complex subunit 7) Canis lupus familiaris
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Symbol: ANAPC7
Name: anaphase promoting complex subunit 7
RGD ID: 12275454
Description: ENCODES a protein that exhibits enzyme-substrate adaptor activity (inferred); protein phosphatase binding (inferred); INVOLVED IN anaphase-promoting complex-dependent catabolic process (inferred); brain development (inferred); protein branched polyubiquitination (inferred); ASSOCIATED WITH FERGUSON-BONNI NEURODEVELOPMENTAL SYNDROME (ortholog); syndromic intellectual disability (ortholog); FOUND IN anaphase-promoting complex (inferred); heterochromatin (inferred); microtubule cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anaphase-promoting complex subunit 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,223,627 - 8,247,976 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,223,616 - 8,247,976 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha268,387,801 - 8,411,922 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,481,772 - 8,505,938 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,481,772 - 8,505,947 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1268,441,423 - 8,465,552 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,499,836 - 8,523,967 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,456,732 - 8,481,089 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ANAPC7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,223,627 - 8,247,976 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,223,616 - 8,247,976 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha268,387,801 - 8,411,922 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,481,772 - 8,505,938 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,481,772 - 8,505,947 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1268,441,423 - 8,465,552 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,499,836 - 8,523,967 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,456,732 - 8,481,089 (-)NCBIUU_Cfam_GSD_1.0
ANAPC7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812110,372,900 - 110,403,708 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12110,372,900 - 110,403,730 (-)EnsemblGRCh38hg38GRCh38
GRCh3712110,810,705 - 110,841,513 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612109,296,332 - 109,325,815 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412109,274,668 - 109,304,152NCBI
Celera12110,436,800 - 110,468,040 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12107,829,309 - 107,860,504 (-)NCBIHuRef
CHM1_112110,778,517 - 110,809,364 (-)NCBICHM1_1
T2T-CHM13v2.012110,350,557 - 110,381,372 (-)NCBIT2T-CHM13v2.0
Anapc7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395122,559,646 - 122,582,978 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5122,559,756 - 122,582,975 (+)EnsemblGRCm39 Ensembl
GRCm385122,422,444 - 122,444,912 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5122,421,693 - 122,444,912 (+)EnsemblGRCm38mm10GRCm38
MGSCv375122,872,453 - 122,894,921 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365122,683,098 - 122,705,196 (+)NCBIMGSCv36mm8
Celera5119,500,990 - 119,523,481 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.36NCBI
Anapc7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,793,518 - 39,821,614 (-)NCBIGRCr8
mRatBN7.21234,131,214 - 34,160,819 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1234,133,429 - 34,160,005 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,305,959 - 35,333,235 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,917,387 - 35,944,658 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,969,698 - 34,996,973 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,613,898 - 39,641,999 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,614,733 - 39,641,285 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,493,496 - 41,521,596 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41235,327,644 - 35,354,839 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11235,191,632 - 35,217,554 (-)NCBI
Celera1235,804,628 - 35,831,847 (-)NCBICelera
Cytogenetic Map12q16NCBI
Anapc7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554827,302,455 - 7,328,145 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554827,302,853 - 7,328,145 (-)NCBIChiLan1.0ChiLan1.0
ANAPC7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210118,438,263 - 118,469,981 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112118,434,665 - 118,466,384 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012107,946,756 - 107,977,489 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112111,338,045 - 111,368,480 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12111,338,045 - 111,368,466 (-)Ensemblpanpan1.1panPan2
Anapc7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118156,088,129 - 156,113,690 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365583,363,807 - 3,391,438 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365583,365,729 - 3,391,292 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANAPC7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1431,763,243 - 31,789,750 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11431,744,729 - 31,789,750 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21433,692,333 - 33,718,027 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANAPC7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111105,612,881 - 105,640,147 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037139,480,089 - 139,508,447 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Anapc7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474721,473,352 - 21,499,843 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474721,473,337 - 21,501,348 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ANAPC7
215 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014108057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022410286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038436622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038436623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038436624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038511538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038511539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038511540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038575038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038575039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038639217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038639218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_543390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000013409   ⟹   ENSCAFP00000012409
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl268,223,616 - 8,247,976 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000063452   ⟹   ENSCAFP00000062808
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl268,225,524 - 8,247,976 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845049178   ⟹   ENSCAFP00845038589
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl268,481,772 - 8,505,947 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845049252   ⟹   ENSCAFP00845038652
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl268,483,016 - 8,505,947 (-)Ensembl
RefSeq Acc Id: XM_014108057   ⟹   XP_013963532
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1268,223,627 - 8,247,915 (-)NCBI
Dog10K_Boxer_Tasha268,387,801 - 8,411,861 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038436622   ⟹   XP_038292550
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0268,481,772 - 8,505,938 (-)NCBI
RefSeq Acc Id: XM_038436623   ⟹   XP_038292551
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0268,481,772 - 8,505,877 (-)NCBI
RefSeq Acc Id: XM_038436624   ⟹   XP_038292552
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0268,481,772 - 8,505,765 (-)NCBI
RefSeq Acc Id: XM_038511538   ⟹   XP_038367466
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1268,441,423 - 8,465,552 (-)NCBI
RefSeq Acc Id: XM_038511539   ⟹   XP_038367467
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1268,441,423 - 8,465,491 (-)NCBI
RefSeq Acc Id: XM_038511540   ⟹   XP_038367468
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1268,441,423 - 8,465,379 (-)NCBI
RefSeq Acc Id: XM_038575038   ⟹   XP_038430966
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0268,456,732 - 8,481,089 (-)NCBI
RefSeq Acc Id: XM_038575039   ⟹   XP_038430967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0268,456,732 - 8,481,028 (-)NCBI
RefSeq Acc Id: XM_038639217   ⟹   XP_038495145
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0268,499,836 - 8,523,967 (-)NCBI
RefSeq Acc Id: XM_038639218   ⟹   XP_038495146
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0268,499,836 - 8,523,906 (-)NCBI
RefSeq Acc Id: XM_543390   ⟹   XP_543390
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1268,223,627 - 8,247,976 (-)NCBI
Dog10K_Boxer_Tasha268,387,801 - 8,411,922 (-)NCBI
Sequence:
RefSeq Acc Id: XP_543390   ⟸   XM_543390
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T6K5 (UniProtKB/TrEMBL),   A0A8I3S6H6 (UniProtKB/TrEMBL),   A0A8I3Q321 (UniProtKB/TrEMBL),   A0A8P0PBL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013963532   ⟸   XM_014108057
- Peptide Label: isoform X3
- UniProtKB: A0A8I3Q321 (UniProtKB/TrEMBL),   A0A8P0PBL4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000062808   ⟸   ENSCAFT00000063452
Ensembl Acc Id: ENSCAFP00000012409   ⟸   ENSCAFT00000013409
RefSeq Acc Id: XP_038367466   ⟸   XM_038511538
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038367467   ⟸   XM_038511539
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038367468   ⟸   XM_038511540
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038495145   ⟸   XM_038639217
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038495146   ⟸   XM_038639218
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038292550   ⟸   XM_038436622
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T6K5 (UniProtKB/TrEMBL),   A0A8I3S6H6 (UniProtKB/TrEMBL),   A0A8I3Q321 (UniProtKB/TrEMBL),   A0A8P0PBL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038292551   ⟸   XM_038436623
- Peptide Label: isoform X3
- UniProtKB: A0A8I3Q321 (UniProtKB/TrEMBL),   A0A8P0PBL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038292552   ⟸   XM_038436624
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038430966   ⟸   XM_038575038
- Peptide Label: isoform X2
- UniProtKB: A0A8C0T6K5 (UniProtKB/TrEMBL),   A0A8I3Q321 (UniProtKB/TrEMBL),   A0A8I3S6H6 (UniProtKB/TrEMBL),   A0A8P0PBL4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038430967   ⟸   XM_038575039
- Peptide Label: isoform X3
- UniProtKB: A0A8I3Q321 (UniProtKB/TrEMBL),   A0A8P0PBL4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845038589   ⟸   ENSCAFT00845049178
Ensembl Acc Id: ENSCAFP00845038652   ⟸   ENSCAFT00845049252


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008442 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030023400 UniProtKB/TrEMBL
  ENSCAFG00040020105 UniProtKB/TrEMBL
  ENSCAFG00845027864 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013409.5 UniProtKB/TrEMBL
  ENSCAFT00000063452.2 UniProtKB/TrEMBL
  ENSCAFT00030043053.1 UniProtKB/TrEMBL
  ENSCAFT00040037219.1 UniProtKB/TrEMBL
  ENSCAFT00845049178 ENTREZGENE
  ENSCAFT00845049178.1 UniProtKB/TrEMBL
  ENSCAFT00845049252.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene ANAPC7 ENTREZGENE
PANTHER ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 UniProtKB/TrEMBL
  CELL DIVISION CYCLE 16,23,27 UniProtKB/TrEMBL
Pfam TPR_16 UniProtKB/TrEMBL
  TPR_8 UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8C0T6K5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q321 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S6H6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PBL4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:52919 ENTREZGENE