| 1303071 | Akap7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding; protein domain specific binding; protein kinase A regulatory subunit binding; INVOLVED IN cAMP/PKA signal transduction; action potential (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vasopressi n signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane; exocytic vesicle; protein-containing complex; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 21906503 | 22168663 | Rat | 123 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1350760 | AKAP7 | A-kinase anchoring protein 7 | This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, bu t contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011] | 6 | 131125627 | 131283532 | Human | 125 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1617174 | Akap7 | A kinase anchor protein 7 | Enables protein kinase binding activity. Involved in modulation of chemical synaptic transmission. Located in nucleus. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including brain; cartilage; endocrine gland; genitourinary system; and trachea. Orthologous to human AKAP7 (A-kinase anchoring protein 7). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 25044988 | 25175115 | Mouse | 137 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8804376 | Akap7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding (ortholog); protein domain specific binding (ortholog); protein kinase A binding (ortholog); INVOLVED IN action potential (ortholog); cAMP/PKA signal transduction (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) sign aling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955436 | 11883840 | 12002668 | Chinchilla | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12017519 | AKAP7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding (ortholog); protein domain specific binding (ortholog); protein kinase A regulatory subunit binding (ortholog); INVOLVED IN action potential (ortholog); cAMP/PKA signal transduction (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane (ortholog); exocytic vesicle (ortholog); lateral plasma membrane (ortholog) | 6 | 128936583 | 129084018 | Bonobo | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12120407 | AKAP7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding (ortholog); protein domain specific binding (ortholog); protein kinase A regulatory subunit binding (ortholog); INVOLVED IN action potential (ortholog); cAMP/PKA signal transduction (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane (ortholog); cytosol (ortholog); exocytic vesicle (ortholog) | 1 | 69360664 | 69483102 | Dog | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12527493 | Akap7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding (ortholog); protein domain specific binding (ortholog); protein kinase A regulatory subunit binding (ortholog); INVOLVED IN action potential (ortholog); cAMP/PKA signal transduction (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane (ortholog); exocytic vesicle (ortholog); lateral plasma membrane (ortholog) | NW_004936790 | 223080 | 339078 | Squirrel | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18637382 | AKAP7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding (ortholog); protein domain specific binding (ortholog); protein kinase A regulatory subunit binding (ortholog); INVOLVED IN action potential (ortholog); cAMP/PKA signal transduction (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane (ortholog); exocytic vesicle (ortholog); lateral plasma membrane (ortholog) | | | | Green Monkey | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155248196 | akap7 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14143803 | AKAP7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding (ortholog); protein domain specific binding (ortholog); protein kinase A regulatory subunit binding (ortholog); INVOLVED IN action potential (ortholog); cAMP/PKA signal transduction (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane (ortholog); exocytic vesicle (ortholog); lateral plasma membrane (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925189 | Akap7 | A-kinase anchoring protein 7 | ENCODES a protein that exhibits AMP binding (ortholog); protein domain specific binding (ortholog); protein kinase A binding (ortholog); INVOLVED IN action potential (ortholog); cAMP/PKA signal transduction (ortholog); cellular response to cAMP (ortholog); PARTICIPATES IN protein kinase A (PKA) sign aling pathway; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH substance-related disorder (ortholog); FOUND IN apical plasma membrane (ortholog); exocytic vesicle (ortholog); hippocampal mossy fiber to CA3 synapse (ortholog) | | | | Naked Mole-Rat | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867286 | AKAP7 | A-kinase anchoring protein 7 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155245379 | akap7.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 620829 | Akap5 | A-kinase anchoring protein 5 | ENCODES a protein that exhibits actin binding; adenylate cyclase binding; beta-2 adrenergic receptor binding; INVOLVED IN hippocampus development; maternal process involved in female pregnancy; negative regulation of adenylate cyclase activity; PARTICIPATES IN protein kinase A (PKA) signaling pathwa y; ASSOCIATED WITH Tetany; Alzheimer's disease (ortholog); Cardiomegaly (ortholog); FOUND IN asymmetric synapse; basolateral plasma membrane; dendrite; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 100787169 | 100796712 | Rat | 236 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1345297 | AKAP5 | A-kinase anchoring protein 5 | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The enco ded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008] | 14 | 64465499 | 64474503 | Human | 232 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |