| 1309600 | Ak7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (ortholog); dCMP kinase activity (ortholog); nucleoside diphosphate kinase activity (ortholog); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); P ARTICIPATES IN purine metabolic pathway; ASSOCIATED WITH hydrocephalus (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (ortholog); sperm principal piece (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; atrazine | 6 | 130376499 | 130444674 | Rat | 87 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320025 | AK7 | adenylate kinase 7 | This gene encodes a member of the adenylate kinase family of enzymes. The encoded enzyme is a phosphotransferase that catalyzes the reversible phosphorylation of adenine nucleotides. This enzyme plays a role in energy homeostasis of the cell. Alternative splicing results in multiple transcript varia nts. Mutations in the mouse gene are associated with primary ciliary dyskinesia. [provided by RefSeq, Apr 2017] | 14 | 96392128 | 96489427 | Human | 109 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1617449 | Ak7 | adenylate kinase 7 | Predicted to enable (d)CMP kinase activity; adenylate kinase activity; and nucleoside diphosphate kinase activity. Acts upstream of or within several processes, including axoneme assembly; epithelial cilium movement involved in extracellular fluid movement; and inflammatory response to antigenic sti mulus. Predicted to be located in cytosol; extracellular region; and motile cilium. Predicted to be active in cytoplasm. Is expressed in lung; lung epithelium; and nasal cavity respiratory epithelium. Used to study hydrocephalus and primary ciliary dyskinesia. Human ortholog(s) of this gene implicated in spermatogenic failure 27. Orthologous to human AK7 (adenylate kinase 7). [provided by Alliance of Genome Resources, Apr 2025] | 12 | 105670115 | 105748706 | Mouse | 131 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8936036 | Ak7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (ortholog); dCMP kinase activity (ortholog); nucleoside diphosphate kinase activity (ortholog); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); A SSOCIATED WITH hydrocephalus (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (ortholog); sperm principal piece (ortholog) | NW_004955438 | 18178822 | 18233051 | Chinchilla | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11922843 | AK7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (inferred); ATP binding (inferred); dCMP kinase activity (inferred); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); ASSOCIATED WITH hydrocephalu s (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (inferred); sperm principal piece (inferred) | 14 | 77021880 | 77119037 | Bonobo | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12301385 | AK7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (inferred); ATP binding (inferred); dCMP kinase activity (inferred); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); ASSOCIATED WITH hydrocephalu s (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (inferred); sperm principal piece (inferred) | 8 | 65136750 | 65213589 | Dog | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12478346 | Ak7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (inferred); ATP binding (inferred); dCMP kinase activity (inferred); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); ASSOCIATED WITH hydrocephalu s (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (inferred); motile cilium (inferred); sperm principal piece (inferred) | NW_004936604 | 680237 | 742580 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18924333 | Ak7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (ortholog); dCMP kinase activity (ortholog); nucleoside diphosphate kinase activity (ortholog); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); A SSOCIATED WITH hydrocephalus (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (ortholog); sperm principal piece (ortholog) | | | | Naked Mole-Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625894378 | Ak7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (ortholog); dCMP kinase activity (ortholog); nucleoside diphosphate kinase activity (ortholog); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); A SSOCIATED WITH hydrocephalus (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (ortholog); sperm principal piece (ortholog) | | | | Black Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18504381 | AK7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (inferred); ATP binding (inferred); dCMP kinase activity (inferred); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); ASSOCIATED WITH hydrocephalu s (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (inferred); motile cilium (inferred); sperm principal piece (inferred) | | | | Green Monkey | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246944 | ak7 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14254922 | AK7 | adenylate kinase 7 | ENCODES a protein that exhibits AMP kinase activity (inferred); ATP binding (inferred); dCMP kinase activity (inferred); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); ASSOCIATED WITH hydrocephalu s (ortholog); primary ciliary dyskinesia (ortholog); spermatogenic failure 27 (ortholog); FOUND IN cytosol (inferred); sperm principal piece (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239171 | ak7.S | | | | | | African Clawed Frog | | symbol | gene, null |