Ak7 (adenylate kinase 7) - Rat Genome Database

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Gene: Ak7 (adenylate kinase 7) Heterocephalus glaber
Analyze
Symbol: Ak7
Name: adenylate kinase 7
RGD ID: 18924333
Description: ENCODES a protein that exhibits adenylate kinase activity (inferred); ATP binding (inferred); cytidylate kinase activity (inferred); INVOLVED IN axoneme assembly (ortholog); brain development (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); ASSOCIATED WITH genetic disease (ortholog); hydrocephalus (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247346,942,374 - 7,001,212 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ak7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247346,942,374 - 7,001,212 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AK7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381496,392,128 - 96,489,427 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1496,392,128 - 96,489,427 (+)EnsemblGRCh38hg38GRCh38
GRCh371496,858,465 - 96,955,764 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361495,928,201 - 96,024,865 (+)NCBINCBI36Build 36hg18NCBI36
Build 341495,928,200 - 96,024,866NCBI
Celera1476,914,175 - 77,010,845 (+)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1477,043,535 - 77,140,413 (+)NCBIHuRef
CHM1_11496,797,289 - 96,894,524 (+)NCBICHM1_1
T2T-CHM13v2.01490,623,724 - 90,721,030 (+)NCBIT2T-CHM13v2.0
Ak7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912105,670,115 - 105,748,706 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12105,672,235 - 105,748,706 (+)EnsemblGRCm39 Ensembl
GRCm3812105,703,858 - 105,782,447 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12105,705,976 - 105,782,447 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712106,944,192 - 107,020,657 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612106,107,032 - 106,183,497 (+)NCBIMGSCv36mm8
Celera12106,940,507 - 107,017,130 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1255.95NCBI
Ak7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86130,376,499 - 130,444,674 (+)NCBIGRCr8
mRatBN7.26124,611,789 - 124,679,978 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6124,611,902 - 124,679,961 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6124,734,223 - 124,803,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06125,029,490 - 125,098,470 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06124,389,700 - 124,457,780 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06129,538,648 - 129,606,960 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6129,538,982 - 129,606,932 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06138,732,026 - 138,805,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46129,861,499 - 129,933,903 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16129,865,370 - 129,939,804 (+)NCBI
Celera6122,178,930 - 122,246,130 (+)NCBICelera
Cytogenetic Map6q32NCBI
Ak7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543818,178,822 - 18,233,051 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543818,178,822 - 18,233,051 (+)NCBIChiLan1.0ChiLan1.0
AK7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21597,552,083 - 97,651,326 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11496,768,587 - 96,867,830 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01477,021,880 - 77,119,037 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11496,344,219 - 96,440,415 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1496,344,240 - 96,440,384 (+)Ensemblpanpan1.1panPan2
AK7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1865,136,750 - 65,213,589 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl865,136,705 - 65,213,555 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha864,653,322 - 64,730,381 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0865,409,508 - 65,486,864 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl865,409,456 - 65,486,388 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1865,082,340 - 65,159,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0865,143,563 - 65,220,637 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0865,467,259 - 65,544,215 (+)NCBIUU_Cfam_GSD_1.0
Ak7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086409,339,422 - 9,402,271 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936604680,329 - 742,284 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936604680,237 - 742,580 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7117,609,840 - 117,667,455 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17117,609,791 - 117,667,247 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27124,867,883 - 124,925,586 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AK7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12474,275,451 - 74,376,032 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2474,275,637 - 74,377,562 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605361,426,946 - 61,526,079 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019685   ⟹   ENSHGLP00000019492
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247346,942,374 - 7,001,212 (-)Ensembl
RefSeq Acc Id: XM_004836988   ⟹   XP_004837045
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBI
RefSeq Acc Id: XM_004836989   ⟹   XP_004837046
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBI
RefSeq Acc Id: XM_004836991   ⟹   XP_004837048
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBI
RefSeq Acc Id: XM_021244531   ⟹   XP_021100190
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBI
RefSeq Acc Id: XM_021244534   ⟹   XP_021100193
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBI
RefSeq Acc Id: XM_021244539   ⟹   XP_021100198
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBI
RefSeq Acc Id: XM_021244548   ⟹   XP_021100207
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247346,942,786 - 7,000,453 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021100198   ⟸   XM_021244539
- Peptide Label: isoform X5
- UniProtKB: G5B499 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004837048   ⟸   XM_004836991
- Peptide Label: isoform X7
- UniProtKB: G5B499 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004837046   ⟸   XM_004836989
- Peptide Label: isoform X4
- UniProtKB: G5B499 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100193   ⟸   XM_021244534
- Peptide Label: isoform X3
- UniProtKB: G5B499 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100207   ⟸   XM_021244548
- Peptide Label: isoform X6
- UniProtKB: G5B499 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004837045   ⟸   XM_004836988
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JD49 (UniProtKB/TrEMBL),   G5B499 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021100190   ⟸   XM_021244531
- Peptide Label: isoform X1
- UniProtKB: G5B499 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019492   ⟸   ENSHGLT00000019685


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013961 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019685 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro Adenylat/UMP-CMP_kin UniProtKB/TrEMBL
  DD_AK7 UniProtKB/TrEMBL
  Dpy-30_motif UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report hgl:101715028 UniProtKB/TrEMBL
NCBI Gene Ak7 ENTREZGENE
PANTHER PTHR23359 UniProtKB/TrEMBL
  PTHR23359:SF105 UniProtKB/TrEMBL
Pfam ADK UniProtKB/TrEMBL
  Dpy-30 UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6JD49 ENTREZGENE, UniProtKB/TrEMBL
  G5B499 ENTREZGENE, UniProtKB/TrEMBL