| 1305840 | Abcg4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (ortholog); ATP hydrolysis activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to high density lipoprotein particle stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog ); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (ortholog); endosome (ortholog); endosome membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 8 | 53508005 | 53525314 | Rat | 138 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1314115 | ABCG4 | ATP binding cassette subfamily G member 4 | The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encode d protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1. [provided by RefSeq, Jan 2017] | 11 | 119149052 | 119162666 | Human | 120 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1314116 | Abcg4 | ATP binding cassette subfamily G member 4 | Enables ABC-type sterol transporter activity. Involved in several processes, including cholesterol efflux; cholesterol homeostasis; and positive regulation of cholesterol biosynthetic process. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in endosome membrane. I s expressed in several structures, including genitourinary system; immune system; liver; nervous system; and sensory organ. Orthologous to human ABCG4 (ATP binding cassette subfamily G member 4). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 44184485 | 44199953 | Mouse | 121 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9005928 | Abcg4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (ortholog); ATP hydrolysis activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to high density lipoprotein particle stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog ); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (ortholog); endosome (ortholog); endosome membrane (ortholog) | NW_004955412 | 20256467 | 20270172 | Chinchilla | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12043910 | ABCG4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (inferred); ABC-type transporter activity (inferred); ATP binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (inferred); endomembrane system (inferred); endosome (inferred) | 11 | 113987709 | 114001354 | Bonobo | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12398259 | ABCG4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (inferred); ABC-type transporter activity (inferred); ATP binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (inferred); endomembrane system (inferred); endosome (inferred) | 5 | 14707964 | 14720782 | Dog | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12463159 | Abcg4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (inferred); ABC-type transporter activity (inferred); ATP binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (inferred); endomembrane system (inferred); endosome (inferred) | NW_004936542 | 4090282 | 4106025 | Squirrel | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284136837 | abcg4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14152664 | ABCG4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (inferred); ABC-type transporter activity (inferred); ATP binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (inferred); endomembrane system (inferred); endosome (inferred) | | | | Pig | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18691233 | ABCG4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (inferred); ABC-type transporter activity (inferred); ATP binding (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (inferred); endomembrane system (inferred); endosome (inferred) | | | | Green Monkey | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625963657 | Abcg4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits ABC-type sterol transporter activity (ortholog); ATP hydrolysis activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to high density lipoprotein particle stimulus (ortholog); cellular response to leukemia inhibitory factor (ortholog ); cholesterol efflux (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (ortholog); endosome (ortholog); endosome membrane (ortholog) | | | | Black Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18919109 | Abcg4 | ATP binding cassette subfamily G member 4 | ENCODES a protein that exhibits identical protein binding (ortholog); protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); cholesterol efflux (ortholog); regulation of DNA-templated trans cription (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasmic vesicle (ortholog); endosome (ortholog); endosome membrane (ortholog) | | | | Naked Mole-Rat | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285073880 | abcg4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 288062789 | abcg4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14116703 | HINFP | histone H4 transcription factor | ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN cell cycle G1/S phase transition (inferred); DNA damage checkpoint signaling (inferred); DNA repair (inferred); FOUND IN nucleolus (ortholog) | | | | Pig | 43 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |