Strain Report - Rat Genome Database

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Strain: FHH/Eur

Symbol: FHH/Eur
Strain: FHH
Substrain: Eur
RGD ID: 10015
Citation ID: RRID:RGD_10015
Ontology ID: RS:0000018
Type: inbred
Source: Erasmus University-Rotterdam
Origin: An outbred stock of fawn hooded rats introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock until the mid-1980s, then brother x sister mating initiated by A.P. Provoost to produce two strains designated FHH (also known as FHR) and FHL, which differ in hypertension and proteinuria. The colony was transferred to Erasmus University.
Last Known Status: Unknown



Strain QTL Data
Symbol Name Trait
Bp283 Blood pressure QTL 283 arterial blood pressure trait   (VT:2000000)    
Rf1 Renal disease susceptibility QTL 1 urine protein amount   (VT:0005160)    
Rf3 Renal disease susceptibility QTL 3 urine albumin amount   (VT:0002871)    
Rf4 Renal disease susceptibility QTL 4 total urine protein amount   (VT:0000032)    
Rf5 Renal disease susceptibility QTL 5 total urine protein amount   (VT:0000032)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics These animals have a characteristic early presence of systolic and glomerular hypertension progressive proteinuria (UPV) and albuminuria (UAV) and focal glomerulosclerosis which results in renal failure leading to premature death. 1016