Experimental Data Annotations Click to see Annotation Detail View
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Experimental Data Annotations Click to see Annotation Detail View
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# | Reference Title | Reference Citation |
1. | Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat. | Brown DM, etal., Nat Genet 1996 Jan;12(1):44-51 |
2. | Inbred Strains | Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press |
3. | Update to previous Strain Data | Festing, MFW, Personal Communication Update, Feb-2000 |
4. | RGD Strain RSO annotation pipeline | RGD Automated Pipelines |
5. | Sequence analysis of the complete mitochondrial DNA in 10 commonly used inbred rat strains. | Schlick NE, etal., Am J Physiol Cell Physiol. 2006 Dec;291(6):C1183-92. Epub 2006 Jul 19. |
6. | Evidence of gene-gene interactions in the genetic susceptibility to renal impairment after unilateral nephrectomy. | Shiozawa M, etal., J Am Soc Nephrol 2000 Nov;11(11):2068-78. |
7. | Pathogenesis of glomerular injury in the fawn-hooded rat: early glomerular capillary hypertension predicts glomerular sclerosis. | Simons JL, etal., J Am Soc Nephrol 1993 May;3(11):1775-82. |
8. | A high density integrated genetic linkage and radiation hybrid map of the laboratory rat | Steen RG, Kwitek-Black AE, etal., Genome Research, 1999, 6:1-8 |
9. | Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat. | van Dokkum RP, etal., Am J Physiol 1999 Mar;276(3 Pt 2):R855-63 |
Symbol | Name | Trait |
Bp283 | Blood pressure QTL 283 |
arterial blood pressure trait (VT:2000000)
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Rf1 | Renal disease susceptibility QTL 1 |
urine protein amount (VT:0005160)
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Rf3 | Renal disease susceptibility QTL 3 |
urine albumin amount (VT:0002871)
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Rf4 | Renal disease susceptibility QTL 4 |
urine total protein amount (VT:0000032)
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Rf5 | Renal disease susceptibility QTL 5 |
urine total protein amount (VT:0000032)
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Note Type | Note | Reference |
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strain_characteristics | These animals have a characteristic early presence of systolic and glomerular hypertension progressive proteinuria (UPV) and albuminuria (UAV) and focal glomerulosclerosis which results in renal failure leading to premature death. | 1016 |