GWAS1791553_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1791553_H (blood VLDL cholesterol amount QTL GWAS1791553 (human)) Homo sapiens

Symbol: GWAS1791553_H
Name: blood VLDL cholesterol amount QTL GWAS1791553 (human)
RGD ID: 598072254
Trait: blood HDL cholesterol amount   (VT:0000184)    
blood HDL phospholipid amount   (VT:0010504)    
blood HDL triglyceride amount   (VT:0010698)    
blood LDL triglyceride amount   (VT:0010699)    
blood lipid amount   (VT:0003949)    
blood phospholipid amount   (VT:0006084)    
blood VLDL cholesterol amount   (VT:0005144)    
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
blood high density lipoprotein phospholipid level   (CMO:0001565)    
blood very low density lipoprotein triglyceride level   (CMO:0002688)    
LOD Score: Not Available
P Value: 1E-200
Variance: Not Available
Position No map positions available.
Population Stats: Not Available




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1791553_HHumanblood high density lipoprotein cholesterol level  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood high density lipoprotein phospholipid level  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood very low density lipoprotein triglyceride level  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1791553_HHumanblood HDL cholesterol amount  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood HDL phospholipid amount  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood HDL triglyceride amount  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood LDL triglyceride amount  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood lipid amount  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood phospholipid amount  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567
GWAS1791553_HHumanblood VLDL cholesterol amount  IAGPrs1601935405850206Based on the EFO term IDGWAS_CATALOGPMID:36764567

1 to 20 of 25 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1791553_HHumanblood VLDL cholesterol amount  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumancholesterol in large HDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumancholesterol in very large HDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumancholesterol in very small VLDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumancholesteryl ester measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanfree cholesterol in HDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanfree cholesterol in large HDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanfree cholesterol in very small VLDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanfree cholesterol to total lipids in medium HDL percentage  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanfree cholesterol to total lipids in very large HDL percentage  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanHDL particle size  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanphosphatidylcholine measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanphospholipids in large HDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanphospholipids in very large HDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanphospholipids in very small VLDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumanphospholipids:total lipids ratio  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumantotal lipids in large HDL  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumantotal lipids in very large HDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
GWAS1791553_HHumantotal lipids in very small VLDL measurement  IAGPrs1601935405850206 GWAS_CATALOGPMID:36764567
1 to 20 of 25 rows

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs1601935)
Human AssemblyChrPosition (strand)Source
GRCh381558,379,566 - 58,379,567RGD_MAPPER_PIPELINE



1 to 20 of 97 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1791553_H GCST90269613 Concentration of very small VLDL particles (UKB data field 23516) 88,329 European ancestry individuals G 0.344751 1E-200 200 rs1601935 0.178016 blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:36764567
GWAS1113068_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.344 1E-22 22 rs1601935 0.048 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113069_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.33 0.000004 5.398 rs1601935 0.08 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1113070_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 2E-26 25.699 rs1601935 0.047 total cholesterol measurement (EFO:0004574)
 PMID:29507422
GWAS1748376_H GCST90093050 Triglyceride levels in chylomicrons and extremely large VLDL 115,082 European ancestry individuals G 0.345362 3E-25 24.523 rs1601935 0.0438758 triglyceride measurement (EFO:0004530)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1750082_H GCST90093036 Phospholipid levels in very small VLDL 115,082 European ancestry individuals G 0.345362 2E-425 424.699 rs1601935 0.188894 phospholipid measurement (EFO:0004639)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1750193_H GCST90093035 Concentration of very small VLDL particles 115,082 European ancestry individuals G 0.345362 7E-368 367.155 rs1601935 0.176041 blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1758294_H GCST90093032 Free cholesterol levels in very small VLDL 115,082 European ancestry individuals G 0.345362 1E-354 354 rs1601935 0.172105 free cholesterol measurement (EFO:0008591)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1758371_H GCST90093046 Total lipid levels in chylomicrons and extremely large VLDL 115,082 European ancestry individuals G 0.345362 2E-12 11.699 rs1601935 0.0296918 lipid measurement (EFO:0004529)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1758604_H GCST90093034 Total lipid levels in very small VLDL 115,082 European ancestry individuals G 0.345362 3E-413 412.523 rs1601935 0.185758 lipid measurement (EFO:0004529)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1759764_H GCST90092828 Average diameter for HDL particles 115,082 European ancestry individuals G 0.345362 2E-436 435.699 rs1601935 0.172638 HDL particle size (OBA:2050115)
 PMID:35213538
GWAS1779456_H GCST90092889 Average diameter for LDL particles 115,082 European ancestry individuals G 0.345362 1E-14 14 rs1601935 0.0330269 LDL particle size (OBA:2050113)
 PMID:35213538
GWAS1484798_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.344 2E-13 12.699 rs1601935 0.033 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1484799_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 2E-15 14.699 rs1601935 0.032 triglyceride measurement (EFO:0004530)
 PMID:29507422
GWAS1780135_H GCST90093038 Triglyceride levels in very small VLDL 115,082 European ancestry individuals G 0.345362 9E-381 380.046 rs1601935 0.177295 triglyceride measurement (EFO:0004530)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1492510_H GCST90094888 Phosphatidylethanolamine (36:2) levels 650 Amish individuals T 0.663265288 4E-8 7.398 rs1601935 0.29902214 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35393526
GWAS1496343_H GCST002896 Cholesterol, total up to 62,166 European ancestry individuals G 0.36 8E-21 20.097 rs1601935 0.059 total cholesterol measurement (EFO:0004574)
 PMID:25961943
GWAS1499986_H GCST008035 High density lipoprotein cholesterol levels 10,085 African American individuals, 17,751 Hispanic/Latino individuals, 2,378 Asian ancestry individuals, 1,912 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 333 individuals ? NR 1E-8 8 rs1601935 0.6818313 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31217584
GWAS1503633_H GCST90102099 Phosphatidylethanolamine (34:2) levels 650 Amish individuals T 0.663265288 2E-7 6.699 rs1601935 0.28775838 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35393526
GWAS1503920_H GCST90102102 Phosphatidylethanolamine (36:4) levels 650 Amish individuals T 0.663265288 3E-8 7.523 rs1601935 0.28865105 phosphatidylethanolamine measurement (EFO:0010228)
 PMID:35393526
1 to 20 of 97 rows
1 to 27 of 27 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90269506 GWAS Catalog
  GCST90269507 GWAS Catalog
  GCST90269519 GWAS Catalog
  GCST90269530 GWAS Catalog
  GCST90269534 GWAS Catalog
  GCST90269613 GWAS Catalog
  GCST90269614 GWAS Catalog
  GCST90269615 GWAS Catalog
  GCST90269616 GWAS Catalog
  GCST90269617 GWAS Catalog
  GCST90269618 GWAS Catalog
  GCST90269619 GWAS Catalog
  GCST90269648 GWAS Catalog
  GCST90269649 GWAS Catalog
  GCST90269650 GWAS Catalog
  GCST90269651 GWAS Catalog
  GCST90269652 GWAS Catalog
  GCST90269655 GWAS Catalog
  GCST90269656 GWAS Catalog
  GCST90269657 GWAS Catalog
  GCST90269658 GWAS Catalog
  GCST90269660 GWAS Catalog
  GCST90269715 GWAS Catalog
  GCST90269720 GWAS Catalog
  GCST90269726 GWAS Catalog
  GCST90269729 GWAS Catalog
  GCST90269739 GWAS Catalog
1 to 27 of 27 rows

Note Type Note Reference