GWAS1678350_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1678350_H (Varicose veins QTL GWAS1678350 (human)) Homo sapiens

Symbol: GWAS1678350_H
Name: Varicose veins QTL GWAS1678350 (human)
RGD ID: 597621490
Trait: Varicose veins
LOD Score: Not Available
P Value: 2.0E-24
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38110,765,520 - 10,765,521RGD_MAPPER_PIPELINEGRCh38
GRCh37110,825,577 - 10,825,578RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1678350_HHumanVaricose veins  IAGPrs11121615405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1606535CASZ1castor zinc finger 111063660410796646Human


Peak: (rs11121615)
Human AssemblyChrPosition (strand)Source
GRCh38110,765,520 - 10,765,521RGD_MAPPER_PIPELINE


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597169496GWAS1265570_HVaricose veins QTL GWAS1265570 (human)1e-103Varicose veins11076552010765521Human
597323549GWAS1419623_HVaricose veins QTL GWAS1419623 (human)8e-67Varicose veins11076552010765521Human
597041087GWAS1137161_Happendicular lean mass QTL GWAS1137161 (human)2e-13appendicular lean mass11076552010765521Human
597111004GWAS1207078_HVaricose veins QTL GWAS1207078 (human)3e-76Varicose veins11076552010765521Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597621490GWAS1678350_HVaricose veins QTL GWAS1678350 (human)2e-24Varicose veins11076552010765521Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
597621486GWAS1678346_HVaricose veins QTL GWAS1678346 (human)1e-31Varicose veins11076552010765521Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human

1 to 10 of 15 rows


1 to 10 of 10 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1678350_H GCST90480225 Varicose veins (PheCode 454) 3,597 African American or Afro-Caribbean cases, 114,779 African American or Afro-Caribbean controls, 18,481 European ancestry cases, 416,199 European ancestry controls, 2,155 Hispanic or Latin American cases, 55,722 Hispanic or Latin American controls C 0.4373 2E-24 23.699 rs11121615 0.1136 Varicose veins (HP:0002619)
 PMID:39024449
GWAS1647805_H GCST90476012 Varicose veins (PheCode 454) 18,481 European ancestry cases, 416,199 European ancestry controls C 0.3297 6E-26 25.222 rs11121615 0.1232 Varicose veins (HP:0002619)
 PMID:39024449
GWAS1647815_H GCST90476013 Varicose veins of lower extremity (PheCode 454.1) 15,944 European ancestry cases, 422,577 European ancestry controls C 0.3297 1E-30 30 rs11121615 0.1445 Varicose veins (HP:0002619)
 PMID:39024449
GWAS1137161_H GCST009577 Appendicular lean mass 181,862 European ancestry elderly individuals T 0.690136 2E-13 12.699 rs11121615 0.0550427 appendicular lean mass (EFO:0004980)
 PMID:31761296
GWAS1204782_H GCST007225 Varicose veins 9,577 British ancestry cases, 327,959 British ancestry controls T 0.69 4E-65 64.398 rs11121615 0.263 Varicose veins (HP:0002619)
 PMID:30566020
GWAS1207078_H GCST008057 Varicose veins 10,861 British ancestry cases, 397,594 British ancestry controls T 0.691425 3E-76 75.523 rs11121615 0.0070457 Varicose veins (HP:0002619)
 PMID:30998689
GWAS1678346_H GCST90480224 Varicose veins of lower extremity (PheCode 454.1) 2,757 African American or Afro-Caribbean cases, 116,810 African American or Afro-Caribbean controls, 15,944 European ancestry cases, 422,577 European ancestry controls, 1,610 Hispanic or Latin American cases, 56,930 Hispanic or Latin American controls C 0.4374 1E-31 31 rs11121615 0.1407 Varicose veins (HP:0002619)
 PMID:39024449
GWAS1265570_H GCST90018939 Varicose veins 22,037 European ancestry cases, 437,665 European ancestry controls, 474 East Asian ancestry cases, 178,252 East Asian ancestry controls T NR 1E-103 103 rs11121615 0.2466 Varicose veins (HP:0002619)
 PMID:34594039
GWAS1325994_H GCST90000025 Appendicular lean mass 450,243 European ancestry individuals T 0.6894 2E-22 21.699 rs11121615 0.02 appendicular lean mass (EFO:0004980)
 PMID:33097823
GWAS1419623_H GCST90246234 Varicose veins 17,027 Finnish ancestry cases, 190,028 Finnish ancestry controls ? NR 8E-67 66.097 rs11121615 0.2388 Varicose veins (HP:0002619)
 PMID:36653477
1 to 10 of 10 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90480225 GWAS Catalog

Note Type Note Reference