GWAS1673326_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1673326_H (Genu varum, Genu valgum QTL GWAS1673326 (human)) Homo sapiens

Symbol: GWAS1673326_H
Name: Genu varum, Genu valgum QTL GWAS1673326 (human)
RGD ID: 597616466
Trait: Genu varum, Genu valgum
LOD Score: Not Available
P Value: 2.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38115,122,489 - 15,122,490RGD_MAPPER_PIPELINEGRCh38
GRCh37115,448,985 - 15,448,986RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1673326_HHumanGenu valgum  IAGPrs180691026405850206 GWAS_CATALOGPMID:39024449
GWAS1673326_HHumanGenu varum  IAGPrs180691026405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
2304154TMEM51-AS1TMEM51 antisense RNA 111511181515152464Human


Peak: (rs180691026)
Human AssemblyChrPosition (strand)Source
GRCh38115,122,489 - 15,122,490RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597616466GWAS1673326_HGenu varum, Genu valgum QTL GWAS1673326 (human)2e-12Genu varum, Genu valgum11512248915122490Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1673326_H GCST90480539 Genu valgum or varum (acquired) (PheCode 736.4) 329 African American or Afro-Caribbean cases, 121,167 African American or Afro-Caribbean controls, 1,360 European ancestry cases, 448,154 European ancestry controls, 240 Hispanic or Latin American cases, 59,396 Hispanic or Latin American controls G 0.9994 2E-12 11.699 rs180691026 3.816 Genu varum (HP:0002970)
Genu valgum (HP:0002857)
 PMID:39024449
Database
Acc Id
Source(s)
GWAS Catalog GCST90480539 GWAS Catalog

Note Type Note Reference