GWAS1654230_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1654230_H (lymphocyte count QTL GWAS1654230 (human)) Homo sapiens

Symbol: GWAS1654230_H
Name: lymphocyte count QTL GWAS1654230 (human)
RGD ID: 597597370
Trait: lymphocyte count
Measurement Type: blood lymphocyte count   (CMO:0000031)    
LOD Score: Not Available
P Value: 5.0E-52
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38474,097,332 - 74,097,333RGD_MAPPER_PIPELINEGRCh38
GRCh37474,963,049 - 74,963,050RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1654230_HHumanblood lymphocyte count  IAGPrs9131405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1654230_HHumanlymphocyte count  IAGPrs9131405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
735621CXCL2C-X-C motif chemokine ligand 247409704074099195Human


Peak: (rs9131)
Human AssemblyChrPosition (strand)Source
GRCh38474,097,332 - 74,097,333RGD_MAPPER_PIPELINE


1 to 10 of 29 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597238040GWAS1334114_Hneutrophil-to-lymphocyte ratio QTL GWAS1334114 (human)4e-36neutrophil-to-lymphocyte ratio47409733274097333Human
597610844GWAS1667704_Hneutrophil count QTL GWAS1667704 (human)3e-51neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)47409733274097333Human
597081307GWAS1177381_Hneutrophil count QTL GWAS1177381 (human)9e-325neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)47409733274097333Human
597598096GWAS1654956_Hlymphocyte count QTL GWAS1654956 (human)1e-26lymphocyte countblood lymphocyte count (CMO:0000031)47409733274097333Human
597104921GWAS1200995_Hneutrophil percentage of leukocytes QTL GWAS1200995 (human)4e-126neutrophil quantity (VT:0000222)blood neutrophil count to total leukocyte count ratio (CMO:0000370)47409733274097333Human
597597329GWAS1654189_Hlymphocyte count QTL GWAS1654189 (human)3e-46lymphocyte countblood lymphocyte count (CMO:0000031)47409733274097333Human
597610769GWAS1667629_Hneutrophil count QTL GWAS1667629 (human)2e-63neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)47409733274097333Human
597587281GWAS1644141_Hneutrophil count QTL GWAS1644141 (human)1e-69neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)47409733274097333Human
596955783GWAS1075302_Hlymphocyte measurement, neutrophil measurement QTL GWAS1075302 (human)1e-73lymphocyte measurement, neutrophil measurement47409733274097333Human
597587085GWAS1643945_Hneutrophil count QTL GWAS1643945 (human)1e-61neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)47409733274097333Human

1 to 10 of 29 rows


1 to 20 of 32 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1654230_H GCST90475435 lymphocyte (fraction, mean, inv-norm transformed) 290,958 European ancestry individuals C 0.4368 5E-52 51.302 rs9131 0.0486 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1637277_H GCST90479666 lymphocyte (fraction, maximum, inv-norm transformed) 81,257 African American or Afro-Caribbean individuals, 40,768 Hispanic or Latin American individuals, 4,294 East Asian ancestry individuals, 290,958 European ancestry individuals C 0.5044 2E-32 31.699 rs9131 0.03967 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1637411_H GCST90479668 lymphocyte (fraction, minimum, inv-norm transformed) 81,257 African American or Afro-Caribbean individuals, 40,768 Hispanic or Latin American individuals, 4,294 East Asian ancestry individuals, 290,958 European ancestry individuals C 0.5044 3E-21 20.523 rs9131 0.02874 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1637895_H GCST90479667 lymphocyte (fraction, mean, inv-norm transformed) 81,257 African American or Afro-Caribbean individuals, 40,768 Hispanic or Latin American individuals, 4,294 East Asian ancestry individuals, 290,958 European ancestry individuals C 0.5044 2E-35 34.699 rs9131 0.04108 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1643945_H GCST90475541 neutrophil (fraction, minimum, inv-norm transformed) 261,863 European ancestry individuals C 0.4367 1E-61 61 rs9131 0.05841 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1644141_H GCST90475538 neutrophil (fraction, mean, inv-norm transformed) 261,847 European ancestry individuals C 0.4367 1E-69 69 rs9131 0.06195 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1645982_H GCST90479704 monocyte (fraction, maximum, inv-norm transformed) 82,924 African American or Afro-Caribbean individuals, 45,327 Hispanic or Latin American individuals, 4,359 East Asian ancestry individuals, 296,975 European ancestry individuals C 0.5032 3E-32 31.523 rs9131 0.04227 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1648547_H GCST90479715 neutrophil (fraction, minimum, inv-norm transformed) 65,556 African American or Afro-Caribbean individuals, 38,543 Hispanic or Latin American individuals, 3,443 East Asian ancestry individuals, 261,863 European ancestry individuals C 0.4967 5E-47 46.302 rs9131 0.05191 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS612984_H GCST004623 Neutrophil percentage of granulocytes 170,672 European ancestry individuals T 0.6014 8E-17 16.097 rs9131 0.03042804 neutrophil percentage of granulocytes (EFO:0007994)
 PMID:27863252
GWAS615751_H GCST004617 Eosinophil percentage of granulocytes 170,536 European ancestry individuals T 0.6014 4E-12 11.398 rs9131 0.02531813 eosinophil percentage of granulocytes (EFO:0007996)
 PMID:27863252
GWAS1650688_H GCST90475300 eosinophil (fraction, mean, inv-norm transformed) 335,542 European ancestry individuals C 0.4367 2E-18 17.699 rs9131 0.02973 eosinophil count (EFO:0004842)
 PMID:39024449
GWAS1152449_H GCST90002380 Basophil percentage of white cells 408,112 British individuals T 0.600913 3E-19 18.523 rs9131 0.020332322 basophil percentage of leukocytes (EFO:0007992)
 PMID:32888494
GWAS1654189_H GCST90475432 lymphocyte (fraction, maximum, inv-norm transformed) 290,958 European ancestry individuals C 0.4368 3E-46 45.523 rs9131 0.04662 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1654956_H GCST90475438 lymphocyte (fraction, minimum, inv-norm transformed) 290,958 European ancestry individuals C 0.4368 1E-26 26 rs9131 0.03279 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1177381_H GCST90002355 Neutrophil count 627,215 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals T 0.572933 9E-325 324.046 rs9131 N/A neutrophil count (EFO:0004833)
 PMID:32888493
GWAS1177924_H GCST90002389 Lymphocyte percentage of white cells 408,112 British individuals T 0.60098 6E-92 91.222 rs9131 0.04590991 lymphocyte percentage of leukocytes (EFO:0007993)
 PMID:32888494
GWAS1659344_H GCST90475511 monocyte (fraction, mean, inv-norm transformed) 296,975 European ancestry individuals C 0.4368 5E-49 48.302 rs9131 0.05363 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1666843_H GCST90479706 monocyte (fraction, minimum, inv-norm transformed) 82,924 African American or Afro-Caribbean individuals, 45,327 Hispanic or Latin American individuals, 4,359 East Asian ancestry individuals, 296,975 European ancestry individuals C 0.5032 2E-22 21.699 rs9131 0.03445 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1667078_H GCST90479705 monocyte (fraction, mean, inv-norm transformed) 82,924 African American or Afro-Caribbean individuals, 45,327 Hispanic or Latin American individuals, 4,359 East Asian ancestry individuals, 296,975 European ancestry individuals C 0.5032 2E-39 38.699 rs9131 0.05087 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1200995_H GCST90002399 Neutrophil percentage of white cells 408,112 British individuals T 0.600963 4E-126 125.398 rs9131 0.053979196 neutrophil percentage of leukocytes (EFO:0007990)
 PMID:32888494
1 to 20 of 32 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90475435 GWAS Catalog

Note Type Note Reference