GWAS1649360_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1649360_H (high density lipoprotein cholesterol measurement QTL GWAS1649360 (human)) Homo sapiens

Symbol: GWAS1649360_H
Name: high density lipoprotein cholesterol measurement QTL GWAS1649360 (human)
RGD ID: 597592500
Trait: high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 8.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3819,181,780 - 9,181,781RGD_MAPPER_PIPELINEGRCh38
GRCh3719,241,839 - 9,241,840RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1649360_HHumanblood high density lipoprotein cholesterol level  IAGPrs79412885405850206 GWAS_CATALOGPMID:39024449

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1649360_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs79412885405850206 GWAS_CATALOGPMID:39024449

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
10401741MIR34AHGMIR34A host gene191480119182338Human
155634346LOC127267331H3K4me1 hESC enhancer GRCh37_chr1:9240951-9241812191808929181815Human
155632022LOC127267332H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:9241813-9242673191817549182675Human


Peak: (rs79412885)
Human AssemblyChrPosition (strand)Source
GRCh3819,181,780 - 9,181,781RGD_MAPPER_PIPELINE


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597382107GWAS1478181_Hmonocyte count QTL GWAS1478181 (human)1e-18monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)191817809181781Human
597358683GWAS1454757_Hmonocyte percentage of leukocytes QTL GWAS1454757 (human)8e-14monocyte quantity (VT:0000223)blood monocyte count to total leukocyte count ratio (CMO:0000374)191817809181781Human
597381434GWAS1477508_Hmonocyte percentage of leukocytes QTL GWAS1477508 (human)1e-26monocyte quantity (VT:0000223)blood monocyte count to total leukocyte count ratio (CMO:0000374)191817809181781Human
597588985GWAS1645845_Hmonocyte count QTL GWAS1645845 (human)5e-16monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)191817809181781Human
597415250GWAS1511324_Hlymphocyte:monocyte ratio QTL GWAS1511324 (human)5e-08leukocyte quantity (VT:0000217)191817809181781Human
597592500GWAS1649360_Hhigh density lipoprotein cholesterol measurement QTL GWAS1649360 (human)8e-12high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)191817809181781Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
597601808GWAS1658668_Hmonocyte count QTL GWAS1658668 (human)2e-15monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)191817809181781Human

1 to 10 of 18 rows


1 to 13 of 13 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1649360_H GCST90475352 high density lipoprotein cholesterol (HDLC, mean, inv-norm transformed) 404,121 European ancestry individuals G 0.9367 8E-12 11.097 rs79412885 0.04321 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:39024449
GWAS1645845_H GCST90479705 monocyte (fraction, mean, inv-norm transformed) 82,924 African American or Afro-Caribbean individuals, 45,327 Hispanic or Latin American individuals, 4,359 East Asian ancestry individuals, 296,975 European ancestry individuals G 0.9502 5E-16 15.302 rs79412885 0.06856 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1658668_H GCST90475514 monocyte (fraction, minimum, inv-norm transformed) 296,975 European ancestry individuals G 0.9368 2E-15 14.699 rs79412885 0.05271 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1659648_H GCST90475508 monocyte (fraction, maximum, inv-norm transformed) 296,975 European ancestry individuals G 0.9368 1E-17 17 rs79412885 0.05558 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1659810_H GCST90475511 monocyte (fraction, mean, inv-norm transformed) 296,975 European ancestry individuals G 0.9368 3E-30 29.523 rs79412885 0.07818 monocyte count (EFO:0005091)
 PMID:39024449
GWAS1665156_H GCST90475124 Aspartate aminotransferase (AST, minimum, inv-norm transformed) 389,315 European ancestry individuals G 0.9365 3E-11 10.523 rs79412885 0.03794 aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934)
 PMID:39024449
GWAS1454757_H GCST004609 Monocyte percentage of white cells 170,494 European ancestry individuals A 0.077 8E-14 13.097 rs79412885 0.05139473 monocyte percentage of leukocytes (EFO:0007989)
 PMID:27863252
GWAS1455609_H GCST004608 Granulocyte percentage of myeloid white cells 169,545 European ancestry individuals A 0.077 7E-13 12.155 rs79412885 0.04948829 granulocyte percentage of myeloid white cells (EFO:0007997)
 PMID:27863252
GWAS1477508_H GCST90002394 Monocyte percentage of white cells 408,112 British individuals A 0.073492 1E-26 26 rs79412885 0.045981 monocyte percentage of leukocytes (EFO:0007989)
 PMID:32888494
GWAS1478181_H GCST90002393 Monocyte count 408,112 British individuals A 0.07348 1E-18 18 rs79412885 0.03793735 monocyte count (EFO:0005091)
 PMID:32888494
GWAS1505611_H GCST90018944 Aspartate aminotransferase levels 342,990 European ancestry individuals, 150,068 East Asian ancestry individuals A NR 5E-15 14.302 rs79412885 0.0347 aspartate aminotransferase measurement (EFO:0004736)
 PMID:34594039
GWAS1511324_H GCST90085816 Lymphocyte-to-monocyte ratio 334,468 European ancestry, NR ancestry individuals ? NR 5E-8 7.302 rs79412885 N/A lymphocyte:monocyte ratio (EFO:0600088)
 PMID:34469753
GWAS1548145_H GCST90019497 Aspartate aminotransferase levels 341,246 European ancestry individuals, 5,982 African ancestry individuals, 7,313 South Asian ancestry individuals A NR 1E-13 13 rs79412885 0.035 aspartate aminotransferase measurement (EFO:0004736)
 PMID:33462484
1 to 13 of 13 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90475352 GWAS Catalog

Note Type Note Reference