GWAS1635487_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1635487_H (hematocrit QTL GWAS1635487 (human)) Homo sapiens

Symbol: GWAS1635487_H
Name: hematocrit QTL GWAS1635487 (human)
RGD ID: 597578627
Trait: GDH/6PGL endoplasmic bifunctional protein measurement
Measurement Type: hematocrit   (CMO:0000037)    
LOD Score: Not Available
P Value: 1.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381494,378,610 - 94,378,611RGD_MAPPER_PIPELINEGRCh38
GRCh371494,844,947 - 94,844,948RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1635487_HHumanhematocrit  IAGPrs28929474405850206 GWAS_CATALOGPMID:39024449


#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1349357SERPINA1serpin family A member 1149437674794390635Human


Peak: (rs28929474)
Human AssemblyChrPosition (strand)Source
GRCh381494,378,610 - 94,378,611RGD_MAPPER_PIPELINE


1 to 10 of 196 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597176733GWAS1272807_Hprotein measurement QTL GWAS1272807 (human)6e-48protein measurement149437861094378611Human
597051792GWAS1147866_Halpha fetoprotein measurement QTL GWAS1147866 (human)1e-47blood alpha-fetoprotein amount (VT:0010776)149437861094378611Human
597191070GWAS1287144_Hsex hormone-binding globulin measurement QTL GWAS1287144 (human)4e-33sex hormone-binding globulin measurement149437861094378611Human
597182366GWAS1278440_H3-hydroxybutyrate measurement QTL GWAS1278440 (human)1e-18urine ketone body amount (VT:0010724)149437861094378611Human
597254558GWAS1350632_HC-reactive protein measurement QTL GWAS1350632 (human)1e-31protein measurementblood C-reactive protein level (CMO:0003160)149437861094378611Human
597158800GWAS1254874_Hsex hormone-binding globulin measurement QTL GWAS1254874 (human)0.000004sex hormone-binding globulin measurement149437861094378611Human
597284241GWAS1380315_Hcalcium measurement QTL GWAS1380315 (human)2e-44blood LDL cholesterol amount (VT:0000181)blood calcium level (CMO:0000502)149437861094378611Human
597253011GWAS1349085_Halkaline phosphatase measurement QTL GWAS1349085 (human)1e-71alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)149437861094378611Human
597223826GWAS1319900_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS1319900 (human)5e-24body fat percentage149437861094378611Human
597598101GWAS1654961_Haspartate aminotransferase to alanine aminotransferase ratio QTL GWAS1654961 (human)3e-212aspartate aminotransferase to alanine aminotransferase ratioserum aspartate aminotransferase activity level to alanine aminotransferase activity level ratio (CMO:0002245)149437861094378611Human

1 to 10 of 196 rows


1 to 20 of 360 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1635487_H GCST90479629 hematocrit (mean, inv-norm transformed) 114,988 African American or Afro-Caribbean individuals, 55,841 Hispanic or Latin American individuals, 5,964 East Asian ancestry individuals, 407,852 European ancestry individuals C 0.9859 1E-20 20 rs28929474 0.1083 hematocrit (EFO:0004348)
 PMID:39024449
GWAS1697944_H GCST003985 Breast size 33,790 European ancestry individuals ? NR 5E-7 6.302 rs28929474 0.215 breast size (OBA:1000025)
 PMID:27182965
GWAS1635187_H GCST90479640 hemoglobin (minimum, inv-norm transformed) 114,985 African American or Afro-Caribbean individuals, 55,838 Hispanic or Latin American individuals, 5,963 East Asian ancestry individuals, 407,894 European ancestry individuals C 0.9859 4E-14 13.398 rs28929474 0.08006 hemoglobin measurement (EFO:0004509)
 PMID:39024449
GWAS1636011_H GCST90479639 hemoglobin (mean, inv-norm transformed) 114,985 African American or Afro-Caribbean individuals, 55,838 Hispanic or Latin American individuals, 5,963 East Asian ancestry individuals, 407,894 European ancestry individuals C 0.9859 2E-19 18.699 rs28929474 0.1002 hemoglobin measurement (EFO:0004509)
 PMID:39024449
GWAS1636250_H GCST90479638 hemoglobin (maximum, inv-norm transformed) 114,984 African American or Afro-Caribbean individuals, 55,834 Hispanic or Latin American individuals, 5,963 East Asian ancestry individuals, 407,887 European ancestry individuals C 0.9859 6E-20 19.222 rs28929474 0.1054 hemoglobin measurement (EFO:0004509)
 PMID:39024449
GWAS1636719_H GCST90479630 hematocrit (minimum, inv-norm transformed) 114,988 African American or Afro-Caribbean individuals, 55,841 Hispanic or Latin American individuals, 5,964 East Asian ancestry individuals, 407,854 European ancestry individuals C 0.9859 2E-15 14.699 rs28929474 0.08643 hematocrit (EFO:0004348)
 PMID:39024449
GWAS1638098_H GCST90479530 Calcium (mean, inv-norm transformed) 74,137 African American or Afro-Caribbean individuals, 26,932 Hispanic or Latin American individuals, 3,651 East Asian ancestry individuals, 250,885 European ancestry individuals C 0.9859 1E-16 16 rs28929474 0.1079 calcium measurement (EFO:0004838)
 PMID:39024449
GWAS1120634_H GCST005162 Glucagon levels in response to oral glucose tolerance test (fasting) 3,344 Swedish ancestry individuals T 0.028 0.000001 6 rs28929474 0.067 glucagon measurement (EFO:0008463)
glucose tolerance test (EFO:0004307)
 PMID:29093273
GWAS1638415_H GCST90479529 Calcium (maximum, inv-norm transformed) 74,104 African American or Afro-Caribbean individuals, 26,929 Hispanic or Latin American individuals, 3,654 East Asian ancestry individuals, 250,919 European ancestry individuals C 0.9859 3E-15 14.523 rs28929474 0.1054 calcium measurement (EFO:0004838)
 PMID:39024449
GWAS1680333_H GCST90479592 Takes medication for Chronic lung diseases including COPD, Emphysema and Bronchitis? 3,204 African American or Afro-Caribbean cases, 52,301 African American or Afro-Caribbean controls, 26,432 European ancestry cases, 289,236 European ancestry controls, 1,213 Hispanic or Latin American cases, 28,101 Hispanic or Latin American controls C 0.9846 2E-11 10.699 rs28929474 0.2237 drug use measurement (EFO:0007010)
chronic lung disease (EFO:0009910)
 PMID:39024449
GWAS1704713_H GCST010703 Brain morphology (MOSTest) 26,502 European ancestry individuals ? NR 2E-9 8.699 rs28929474 N/A brain attribute (OBA:2045210)
neuroimaging measurement (EFO:0004346)
 PMID:32665545
GWAS568744_H GCST003976 Antineutrophil cytoplasmic antibody-associated vasculitis 1,015 European ancestry granulomatosis with polyangiitis cases, 206 European ancestry microscopic polyangiitis cases, 3,258 European ancestry controls. T 0.02 3E-12 11.523 rs28929474 2.18 anti-neutrophil antibody associated vasculitis (EFO:0004826)
 PMID:28029757
GWAS1705873_H GCST010544 Problematic alcohol use (MTAG) 972,915 European ancestry individuals T 0.0184 2E-12 11.699 rs28929474 0.05428487 alcohol use disorder measurement (EFO:0009458)
alcohol consumption quality (OBA:1000840)
 PMID:32451486
GWAS1706076_H GCST010543 Alcohol consumption (drinks per week) (MTAG) 972,915 European ancestry individuals T 0.0154 2E-14 13.699 rs28929474 0.053747147 alcohol consumption quality (OBA:1000840)
 PMID:32451486
GWAS1708712_H GCST008163 Height 1,249 whole genome sequenced European ancestry individuals, 3,541 whole genome sequenced individuals, 46,910 European ancestry individuals, 471 Carlantino (founder/genetic isolate) individuals, 1,197 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,043 Mylopotamos (founder/genetic isolate) individuals, 933 Pomak (founder/genetic isolate) individuals, 1,785 Val Borbera (founder/genetic isolate) individuals T 0.0189 1E-7 7 rs28929474 0.1346 body height (OBA:VT0001253)
 PMID:28552196
GWAS1647300_H GCST90476027 Chronic airway obstruction (PheCode 496) 103,054 European ancestry cases, 315,450 European ancestry controls C 0.9816 4E-11 10.398 rs28929474 0.1056 chronic obstructive pulmonary disease (EFO:0000341)
 PMID:39024449
GWAS1648051_H GCST90475936 Coronary atherosclerosis (PheCode 411.4) 124,302 European ancestry cases, 300,039 European ancestry controls C 0.9816 5E-15 14.302 rs28929474 0.1361 PMID:39024449
None Available GCST90475929 Ischemic heart disease (PheCode 411) 141,465 European ancestry cases, 275,809 European ancestry controls C 0.9816 2E-15 14.699 rs28929474 0.1322 coronary artery disease (EFO:0001645)
 PMID:39024449
GWAS1144544_H GCST009777 C-reactive protein levels 418,642 British ancestry individuals C 0.979816 3E-49 48.523 rs28929474 0.103242 C-reactive protein measurement (EFO:0004458)
 PMID:31900758
GWAS1650281_H GCST90476316 prostate-specific antigen (PSA, maximum, inv-norm transformed) 254,456 European ancestry individuals C 0.9816 6E-36 35.222 rs28929474 0.1464 prostate specific antigen amount (OBA:2050200)
 PMID:39024449
1 to 20 of 360 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90247714 GWAS Catalog
  GCST90314750 GWAS Catalog
  GCST90479629 GWAS Catalog

Note Type Note Reference