GWAS1577298_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS1577298_H (open-angle glaucoma QTL GWAS1577298 (human)) Homo sapiens

Symbol: GWAS1577298_H
Name: open-angle glaucoma QTL GWAS1577298 (human)
RGD ID: 597481224
Trait: open-angle glaucoma
LOD Score: Not Available
P Value: 9.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3861,548,134 - 1,548,135RGD_MAPPER_PIPELINEGRCh38
GRCh3761,548,369 - 1,548,370RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1577298_HHumanopen-angle glaucoma  IAGPrs2745572405850206 GWAS_CATALOGPMID:33627673

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1577298_HHumanOpen angle glaucoma  IAGPrs2745572405850206 GWAS_CATALOGPMID:33627673
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1577298_HHumanopen-angle glaucoma  IAGPrs2745572405850206 GWAS_CATALOGPMID:33627673

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
38673301LOC102723944uncharacterized LOC102723944614532781555286Human


Peak: (rs2745572)
Human AssemblyChrPosition (strand)Source
GRCh3861,548,134 - 1,548,135RGD_MAPPER_PIPELINE


1 to 10 of 41 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
596955728GWAS1075247_Hintraocular pressure measurement QTL GWAS1075247 (human)7e-20intraocular pressure measurement615481341548135Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597482193GWAS1578267_Hopen-angle glaucoma QTL GWAS1578267 (human)3e-13open-angle glaucoma615481341548135Human
597590160GWAS1647020_Hopen-angle glaucoma QTL GWAS1647020 (human)6e-28open-angle glaucoma615481341548135Human
597591310GWAS1648170_Hglaucoma QTL GWAS1648170 (human)1e-39glaucoma615481341548135Human
597519439GWAS1615513_Hopen-angle glaucoma QTL GWAS1615513 (human)8e-25open-angle glaucoma615481341548135Human
597579148GWAS1636008_Hglaucoma QTL GWAS1636008 (human)1e-24glaucoma615481341548135Human
597590093GWAS1646953_Hopen-angle glaucoma QTL GWAS1646953 (human)6e-33open-angle glaucoma615481341548135Human
597481160GWAS1577234_Hopen-angle glaucoma QTL GWAS1577234 (human)4e-13open-angle glaucoma615481341548135Human

1 to 10 of 41 rows


1 to 20 of 36 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1577298_H GCST90011766 Glaucoma (primary open-angle) 16,677 European ancestry cases, 199,580 European ancestry controls A NR 9E-20 19.046 rs2745572 1.13406 open-angle glaucoma (EFO:0004190)
PMID:33627673
GWAS1111937_H GCST005170 Intraocular pressure 56,819 European ancestry individuals, 5,748 Hispanic/Latino individuals, 5,119 East Asian ancestry individuals, 2,070 African American individuals ? NR 4E-17 16.398 rs2745572 0.11 intraocular pressure measurement (EFO:0004695)
PMID:29235454
GWAS1635929_H GCST90479644 Takes medication for Glaucoma? 4,849 African American or Afro-Caribbean cases, 50,656 African American or Afro-Caribbean controls, 1,360 Hispanic or Latin American cases, 27,954 Hispanic or Latin American controls, 201 East Asian ancestry cases, 3,346 East Asian ancestry controls, 13,744 European ancestry cases, 301,924 European ancestry controls A 0.6776 9E-19 18.046 rs2745572 0.1103 drug use measurement (EFO:0007010)
PMID:39024449
GWAS1636008_H GCST90479645 Glaucoma 6,861 African American or Afro-Caribbean cases, 48,644 African American or Afro-Caribbean controls, 2,207 Hispanic or Latin American cases, 27,107 Hispanic or Latin American controls, 329 East Asian ancestry cases, 3,218 East Asian ancestry controls, 20,090 European ancestry cases, 295,578 European ancestry controls A 0.6776 1E-24 24 rs2745572 0.1073 PMID:39024449
GWAS1646953_H GCST90475875 Primary open angle glaucoma (PheCode 365.11) 20,091 European ancestry cases, 424,364 European ancestry controls A 0.658 6E-33 32.222 rs2745572 0.1273 open-angle glaucoma (EFO:0004190)
PMID:39024449
GWAS1647020_H GCST90475872 Open-angle glaucoma (PheCode 365.1) 56,207 European ancestry cases, 377,826 European ancestry controls A 0.6581 6E-28 27.222 rs2745572 0.06858 open-angle glaucoma (EFO:0004190)
PMID:39024449
GWAS1648170_H GCST90475869 Glaucoma 81,303 European ancestry cases, 349,418 European ancestry controls A 0.6581 1E-39 39 rs2745572 0.0707 PMID:39024449
GWAS1654660_H GCST90475384 Takes medication for Glaucoma? 13,744 European ancestry cases, 301,924 European ancestry controls A 0.6577 3E-20 19.523 rs2745572 0.1227 drug use measurement (EFO:0007010)
PMID:39024449
GWAS1654662_H GCST90475383 Glaucoma 20,090 European ancestry cases, 295,578 European ancestry controls A 0.6577 7E-27 26.155 rs2745572 0.1189 PMID:39024449
None Available GCST90480069 Glaucoma 38,064 African American or Afro-Caribbean cases, 76,856 African American or Afro-Caribbean controls, 11,570 Hispanic or Latin American cases, 45,339 Hispanic or Latin American controls, 1,446 East Asian ancestry cases, 5,057 East Asian ancestry controls, 81,303 European ancestry cases, 349,418 European ancestry controls A 0.6857 6E-28 27.222 rs2745572 0.06228 PMID:39024449
GWAS1677397_H GCST90480066 Primary open angle glaucoma (PheCode 365.11) 13,552 African American or Afro-Caribbean cases, 105,042 African American or Afro-Caribbean controls, 2,857 Hispanic or Latin American cases, 56,071 Hispanic or Latin American controls, 312 East Asian ancestry cases, 6,452 East Asian ancestry controls, 20,091 European ancestry cases, 424,364 European ancestry controls A 0.6856 2E-26 25.699 rs2745572 0.1042 open-angle glaucoma (EFO:0004190)
PMID:39024449
GWAS1677410_H GCST90480067 Open-angle glaucoma (PheCode 365.1) 30,309 African American or Afro-Caribbean cases, 84,722 African American or Afro-Caribbean controls, 8,523 Hispanic or Latin American cases, 48,779 Hispanic or Latin American controls, 1,127 East Asian ancestry cases, 5,402 East Asian ancestry controls, 56,207 European ancestry cases, 377,826 European ancestry controls A 0.6856 3E-19 18.523 rs2745572 0.06081 open-angle glaucoma (EFO:0004190)
PMID:39024449
GWAS1461997_H GCST009725 Intraocular pressure 133,492 European ancestry individuals A 0.67 4E-22 21.398 rs2745572 N/A intraocular pressure measurement (EFO:0004695)
PMID:31959993
GWAS1486075_H GCST009722 Glaucoma (multi-trait analysis) 133,492 European ancestry individuals with intraocular pressure measurements, 90,939 European ancestry individuals with vertical cup-disc ratio measurements, 7,947 British ancestry glaucoma cases, 119,318 British ancestry controls A 0.67 1E-30 30 rs2745572 1.14 PMID:31959993
GWAS1487553_H GCST003342 Glaucoma (primary open-angle) 3,853 European ancestry cases, 33,480 European ancestry controls A 0.66 2E-10 9.699 rs2745572 1.17 open-angle glaucoma (EFO:0004190)
PMID:26752265
GWAS1487879_H GCST003342 Glaucoma (primary open-angle) 3,853 European ancestry cases, 33,480 European ancestry controls A 0.66 5E-12 11.302 rs2745572 1.22 open-angle glaucoma (EFO:0004190)
PMID:26752265
GWAS1487883_H GCST003344 Glaucoma (high intraocular pressure) 1,868 European ancestry cases, 31,497 European ancestry controls A NR 3E-9 8.523 rs2745572 N/A open-angle glaucoma (EFO:0004190)
PMID:26752265
GWAS1489589_H GCST010376 Intraocular pressure 101,939 European ancestry cases A NR 4E-18 17.398 rs2745572 0.14 intraocular pressure measurement (EFO:0004695)
PMID:32352494
GWAS1490696_H GCST009726 Glaucoma 7,947 British ancestry cases, 119,318 British ancestry controls A 0.67 1E-10 10 rs2745572 1.12 PMID:31959993
None Available GCST90129592 Vertical cup-disc ratio 65,680 European ancestry individuals A 0.666 3E-9 8.523 rs2745572 0.00435 cup-to-disc ratio measurement (EFO:0006939)
PMID:34077760
1 to 20 of 36 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90011766 GWAS Catalog

Note Type Note Reference