GWAS1545200_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1545200_H (systolic blood pressure QTL GWAS1545200 (human)) Homo sapiens

Symbol: GWAS1545200_H
Name: systolic blood pressure QTL GWAS1545200 (human)
RGD ID: 597449126
Trait: systolic blood pressure
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 9.0E-21
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3813,412,820 - 3,412,821RGD_MAPPER_PIPELINEGRCh38
GRCh3713,329,384 - 3,329,385RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1545200_HHumansystolic blood pressure  IAGPrs2493291405850206 GWAS_CATALOGPMID:39537608

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1545200_HHumansystolic blood pressure  IAGPrs2493291405850206 GWAS_CATALOGPMID:39537608

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1353101PRDM16PR/SET domain 16130692033438621Human


Peak: (rs2493291)
Human AssemblyChrPosition (strand)Source
GRCh3813,412,820 - 3,412,821RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597227100GWAS1323174_Hrheumatoid arthritis QTL GWAS1323174 (human)2e-14rheumatoid arthritis134128203412821Human
597273742GWAS1369816_Hsystolic blood pressure QTL GWAS1369816 (human)7e-15systolic blood pressuresystolic blood pressure (CMO:0000004)134128203412821Human
597449126GWAS1545200_Hsystolic blood pressure QTL GWAS1545200 (human)9e-21systolic blood pressuresystolic blood pressure (CMO:0000004)134128203412821Human
597281138GWAS1377212_Hdiastolic blood pressure QTL GWAS1377212 (human)5e-15diastolic blood pressurediastolic blood pressure (CMO:0000005)134128203412821Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1545200_H GCST90449056 Systolic blood pressure (MTAG) at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples) T NR 9E-21 20.046 rs2493291 0.023012461 systolic blood pressure (EFO:0006335)
 PMID:39537608
GWAS1323174_H GCST007843 Rheumatoid arthritis 868 European ancestry cases, 1,194 European ancestry controls G 0.881 2E-14 13.699 rs2493291 N/A rheumatoid arthritis (EFO:0000685)
 PMID:30891314
GWAS1369816_H GCST90132903 Systolic blood pressure 526,001 European ancestry individuals T NR 7E-15 14.155 rs2493291 0.4131 systolic blood pressure (EFO:0006335)
 PMID:35762941
GWAS1377212_H GCST90018952 Diastolic blood pressure 340,162 European ancestry individuals, 145,515 East Asian ancestry individuals T NR 5E-15 14.302 rs2493291 0.0269 diastolic blood pressure (EFO:0006336)
 PMID:34594039
Database
Acc Id
Source(s)
GWAS Catalog GCST90449056 GWAS Catalog

Note Type Note Reference