GWAS1519340_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1519340_H (serum alanine aminotransferase measurement QTL GWAS1519340 (human)) Homo sapiens

Symbol: GWAS1519340_H
Name: serum alanine aminotransferase measurement QTL GWAS1519340 (human)
RGD ID: 597423266
Trait: serum alanine aminotransferase measurement
Measurement Type: serum alanine aminotransferase activity level   (CMO:0000575)    
LOD Score: Not Available
P Value: 4.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38116,187,874 - 16,187,875RGD_MAPPER_PIPELINEGRCh38
GRCh37116,514,369 - 16,514,370RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1519340_HHumanserum alanine aminotransferase activity level  IAGPrs4661721405850206 GWAS_CATALOGPMID:33462484

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1519340_HHumanserum alanine aminotransferase measurement  IAGPrs4661721405850206 GWAS_CATALOGPMID:33462484

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs4661721)
Human AssemblyChrPosition (strand)Source
GRCh38116,187,874 - 16,187,875RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597451897GWAS1547971_Hserum gamma-glutamyl transferase measurement QTL GWAS1547971 (human)3e-38serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)11618787416187875Human
597423266GWAS1519340_Hserum alanine aminotransferase measurement QTL GWAS1519340 (human)4e-10serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)11618787416187875Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1519340_H GCST90019492 Alanine aminotransferase levels 342,387 European ancestry individuals, 6,017 African ancestry individuals, 7,325 South Asian ancestry individuals G NR 4E-10 9.398 rs4661721 0.025 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:33462484
GWAS1547971_H GCST90019507 Gamma glutamyl transferase levels 342,339 European ancestry individuals, 6,015 African ancestry individuals, 7,336 South Asian ancestry individuals G NR 3E-38 37.523 rs4661721 0.0518 serum gamma-glutamyl transferase measurement (EFO:0004532)
 PMID:33462484
Database
Acc Id
Source(s)
GWAS Catalog GCST90019492 GWAS Catalog

Note Type Note Reference