GWAS1496623_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1496623_H (FEV/FVC ratio, response to bronchodilator QTL GWAS1496623 (human)) Homo sapiens

Symbol: GWAS1496623_H
Name: FEV/FVC ratio, response to bronchodilator QTL GWAS1496623 (human)
RGD ID: 597400549
Trait: FEV/FVC ratio, response to bronchodilator
Measurement Type: forced expiratory volume to forced vital capacity ratio   (CMO:0000241)    
LOD Score: Not Available
P Value: 3.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38611,785,127 - 11,785,128RGD_MAPPER_PIPELINEGRCh38
GRCh37611,785,360 - 11,785,361RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1496623_HHumanresponse to bronchodilator  IAGPrs185569610405850206 GWAS_CATALOGPMID:26634245


Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1496623_HHumanforced expiratory volume to forced vital capacity ratio  IAGPrs185569610405850206 GWAS_CATALOGPMID:26634245

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1496623_HHumanFEV/FVC ratio  IAGPrs185569610405850206 GWAS_CATALOGPMID:26634245

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs185569610)
Human AssemblyChrPosition (strand)Source
GRCh38611,785,127 - 11,785,128RGD_MAPPER_PIPELINE


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2292824PRSTS5_HProstate tumor susceptibility QTL 5 (human)Prostate tumor susceptibility6119232373Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
1643495BW291_HBody Weight QTL 291 (human)2.13Body weightBMI6119321359Human

1 to 10 of 12 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1496623_H GCST003264 Post bronchodilator FEV1/FVC ratio 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals C 0.999 0.000003 5.523 rs185569610 0.359 FEV/FVC ratio (EFO:0004713)
response to bronchodilator (GO:0097366)
 PMID:26634245
Database
Acc Id
Source(s)
GWAS Catalog GCST003264 GWAS Catalog

Note Type Note Reference