GWAS1493889_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1493889_H (diastolic blood pressure QTL GWAS1493889 (human)) Homo sapiens

Symbol: GWAS1493889_H
Name: diastolic blood pressure QTL GWAS1493889 (human)
RGD ID: 597397815
Trait: diastolic blood pressure
Measurement Type: diastolic blood pressure   (CMO:0000005)    
LOD Score: Not Available
P Value: 3.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38124,695,823 - 24,695,824RGD_MAPPER_PIPELINEGRCh38
GRCh37125,022,314 - 25,022,315RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1493889_HHumandiastolic blood pressure  IAGPrs72654647405850206 GWAS_CATALOGPMID:39134668

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1493889_HHumandiastolic blood pressure  IAGPrs72654647405850206 GWAS_CATALOGPMID:39134668

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs72654647)
Human AssemblyChrPosition (strand)Source
GRCh38124,695,823 - 24,695,824RGD_MAPPER_PIPELINE


1 to 10 of 14 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
597365721GWAS1461795_Hhematocrit QTL GWAS1461795 (human)2e-10systolic blood pressuresystolic blood pressure (CMO:0000004)12469582324695824Human
597393144GWAS1489218_Hhigh density lipoprotein cholesterol measurement QTL GWAS1489218 (human)3e-10high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)12469582324695824Human
596967472GWAS1086991_Hdiastolic blood pressure QTL GWAS1086991 (human)3e-15diastolic blood pressure12469582324695824Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597397815GWAS1493889_Hdiastolic blood pressure QTL GWAS1493889 (human)3e-15diastolic blood pressurediastolic blood pressure (CMO:0000005)12469582324695824Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
597383253GWAS1479327_Herythrocyte count QTL GWAS1479327 (human)2e-15erythrocyte countred blood cell count (CMO:0000025)12469582324695824Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597367658GWAS1463732_Hhemoglobin measurement QTL GWAS1463732 (human)2e-12hemoglobin measurementhemoglobin measurement (CMO:0000508)12469582324695824Human

1 to 10 of 14 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1493889_H GCST90435414 Diastolic blood pressure 404,337 European ancestry individuals ? NR 3E-15 14.523 rs72654647 0.0190834 diastolic blood pressure (EFO:0006336)
 PMID:39134668
GWAS1461795_H GCST90002383 Hematocrit 408,112 British individuals A 0.246719 2E-10 9.699 rs72654647 0.01638399 hematocrit (EFO:0004348)
 PMID:32888494
GWAS1463732_H GCST90002384 Hemoglobin 408,112 British individuals A 0.246726 2E-12 11.699 rs72654647 0.018085852 hemoglobin measurement (EFO:0004509)
 PMID:32888494
GWAS1479327_H GCST007069 Red blood cell count approximately 445,000 European ancestry individuals ? NR 2E-15 14.699 rs72654647 N/A erythrocyte count (EFO:0004305)
 PMID:30595370
GWAS1489218_H GCST010242 HDL cholesterol levels 403,943 European ancestry individuals G 0.752205 3E-10 9.523 rs72654647 0.0138902 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:32203549
GWAS1491216_H GCST90435415 Systolic blood pressure 404,507 European ancestry individuals ? NR 9E-11 10.046 rs72654647 0.0146098 systolic blood pressure (EFO:0006335)
 PMID:39134668
None Available GCST007087 Systolic blood pressure approximately 422,000 European ancestry individuals ? NR 2E-10 9.699 rs72654647 N/A systolic blood pressure (EFO:0006335)
 PMID:30595370
GWAS1517943_H GCST90449056 Systolic blood pressure (MTAG) at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples) A NR 2E-9 8.699 rs72654647 0.011881479 systolic blood pressure (EFO:0006335)
 PMID:39537608
Database
Acc Id
Source(s)
GWAS Catalog GCST90435414 GWAS Catalog

Note Type Note Reference