GWAS1472693_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1472693_H (coronary artery calcification QTL GWAS1472693 (human)) Homo sapiens

Symbol: GWAS1472693_H
Name: coronary artery calcification QTL GWAS1472693 (human)
RGD ID: 597376619
Trait: coronary artery calcification
LOD Score: Not Available
P Value: 4.0E-22
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38612,903,725 - 12,903,726RGD_MAPPER_PIPELINEGRCh38
GRCh37612,903,957 - 12,903,958RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1472693_HHumanAngina Pectoris  IAGPrs9349379405850206 GWAS_CATALOGPMID:34594039
GWAS1472693_HHumanCoronary Artery Calcification  IAGPrs9349379405850206 GWAS_CATALOGPMID:22144573

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1472693_HHumanAngina pectoris  IAGPrs9349379405850206 GWAS_CATALOGPMID:34594039
GWAS1472693_HHumanCoronary artery calcification  IAGPrs9349379405850206 GWAS_CATALOGPMID:22144573
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1472693_HHumanangina pectoris  IAGPrs9349379405850206 GWAS_CATALOGPMID:34594039
GWAS1472693_HHumancoronary artery calcification  IAGPrs9349379405850206 GWAS_CATALOGPMID:22144573

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1353173PHACTR1phosphatase and actin regulator 161271676713287837Human


Peak: (rs9349379)
Human AssemblyChrPosition (strand)Source
GRCh38612,903,725 - 12,903,726RGD_MAPPER_PIPELINE


1 to 10 of 113 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597462684GWAS1558758_HHeadache QTL GWAS1558758 (human)4e-15Headache61290372512903726Human
597594522GWAS1651382_Hdrug use measurement, myocardial infarction QTL GWAS1651382 (human)1e-32drug use measurement, myocardial infarction61290372512903726Human
597437592GWAS1533666_Hangina pectoris QTL GWAS1533666 (human)1e-09angina pectoris61290372512903726Human
597607320GWAS1664180_Hsystolic blood pressure QTL GWAS1664180 (human)6e-22systolic blood pressuresystolic blood pressure (CMO:0000004)61290372512903726Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
597530262GWAS1626336_Hcoronary artery disease QTL GWAS1626336 (human)1e-08coronary artery disease61290372512903726Human
597424784GWAS1520858_Hsystolic blood pressure QTL GWAS1520858 (human)5e-15fibromuscular dysplasiasystolic blood pressure (CMO:0000004)61290372512903726Human
597386389GWAS1482463_Hcoronary artery disease QTL GWAS1482463 (human)1e-35coronary artery disease61290372512903726Human
407268694GWAS917670_Hcoronary artery disease QTL GWAS917670 (human)6e-19coronary artery disease61290372512903726Human
597595278GWAS1652138_Hcoronary artery disease QTL GWAS1652138 (human)3e-47coronary artery disease61290372512903726Human

1 to 10 of 113 rows


1 to 20 of 126 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1472693_H GCST001347 Coronary artery calcification 9,961 European ancestry individuals A NR 4E-22 21.398 rs9349379 0.196 coronary artery calcification (EFO:0004723)
 PMID:22144573
GWAS1111948_H GCST005195 Coronary artery disease up to 122,733 cases, up to 424,528 controls A 0.5907 3E-76 75.523 rs9349379 0.1072 coronary artery disease (EFO:0001645)
 PMID:29212778
GWAS1111964_H GCST005196 Coronary artery disease 88,192 cases, 162,544 controls A 0.5876 3E-77 76.523 rs9349379 0.1205 coronary artery disease (EFO:0001645)
 PMID:29212778
GWAS1638489_H GCST90479543 Coronary artery / coronary heart disease (including heart attack, angina) 5,298 African American or Afro-Caribbean cases, 50,207 African American or Afro-Caribbean controls, 3,107 Hispanic or Latin American cases, 26,207 Hispanic or Latin American controls, 381 East Asian ancestry cases, 3,166 East Asian ancestry controls, 52,789 European ancestry cases, 262,879 European ancestry controls A 0.6439 8E-35 34.097 rs9349379 0.09221 coronary artery disease (EFO:0001645)
 PMID:39024449
GWAS1638802_H GCST90301701 Pulse pressure 349,328 British ancestry individuals A NR 2E-22 21.699 rs9349379 0.02 pulse pressure measurement (EFO:0005763)
 PMID:38459180
GWAS1645724_H GCST90475837 Migraine (PheCode 340) 31,836 European ancestry cases, 405,831 European ancestry controls A 0.5978 3E-12 11.523 rs9349379 0.06017 PMID:39024449
GWAS1646660_H GCST90475991 Atherosclerosis of native arteries of the extremities with intermittent claudication (PheCode 440.22) 9,984 European ancestry cases, 432,329 European ancestry controls A 0.5982 2E-11 10.699 rs9349379 0.09528 atherosclerosis (EFO:0003914)
 PMID:39024449
GWAS1648376_H GCST90475936 Coronary atherosclerosis (PheCode 411.4) 124,302 European ancestry cases, 300,039 European ancestry controls A 0.5978 2E-96 95.699 rs9349379 0.09356 PMID:39024449
GWAS1648382_H GCST90475933 Angina pectoris (PheCode 411.3) 37,399 European ancestry cases, 385,941 European ancestry controls A 0.5985 4E-28 27.398 rs9349379 0.0802 angina pectoris (EFO:0003913)
 PMID:39024449
GWAS1648880_H GCST90475929 Ischemic heart disease (PheCode 411) 141,465 European ancestry cases, 275,809 European ancestry controls A 0.5976 7E-82 81.155 rs9349379 0.08413 coronary artery disease (EFO:0001645)
 PMID:39024449
GWAS1648890_H GCST90475930 Unstable angina (intermediate coronary syndrome) (PheCode 411.1) 16,513 European ancestry cases, 418,345 European ancestry controls A 0.5984 1E-11 11 rs9349379 0.07423 intermediate coronary syndrome (EFO:1000985)
 PMID:39024449
GWAS1648919_H GCST90475932 Myocardial infarction (PheCode 411.2) 39,074 European ancestry cases, 392,979 European ancestry controls A 0.5985 1E-38 38 rs9349379 0.09321 myocardial infarction (EFO:0000612)
 PMID:39024449
None Available GCST90480017 Migraine (PheCode 340) 11,587 African American or Afro-Caribbean cases, 105,664 African American or Afro-Caribbean controls, 5,907 Hispanic or Latin American cases, 51,631 Hispanic or Latin American controls, 541 East Asian ancestry cases, 6,086 East Asian ancestry controls, 31,836 European ancestry cases, 405,831 European ancestry controls A 0.661 3E-12 11.523 rs9349379 0.05738 PMID:39024449
GWAS1651335_H GCST90475211 Heart attack 39,300 European ancestry cases, 276,368 European ancestry controls A 0.5983 1E-37 37 rs9349379 0.09432 myocardial infarction (EFO:0000612)
 PMID:39024449
GWAS1651382_H GCST90475212 Takes medication for heart attack? 33,688 European ancestry cases, 281,980 European ancestry controls A 0.5983 1E-32 32 rs9349379 0.09433 drug use measurement (EFO:0007010)
myocardial infarction (EFO:0000612)
 PMID:39024449
GWAS1652138_H GCST90475198 Coronary artery / coronary heart disease (including heart attack, angina) 52,789 European ancestry cases, 262,879 European ancestry controls A 0.5983 3E-47 46.523 rs9349379 0.09396 coronary artery disease (EFO:0001645)
 PMID:39024449
GWAS1652461_H GCST90475199 Takes medication for coronary artery/ coronary heart disease? 44,681 European ancestry cases, 270,987 European ancestry controls A 0.5983 7E-42 41.155 rs9349379 0.0952 drug use measurement (EFO:0007010)
coronary artery disease (EFO:0001645)
 PMID:39024449
GWAS1713028_H GCST008811 Alcohol consumption (drinks per week) up to 357,854 European ancestry individuals G 0.406 3E-8 7.523 rs9349379 0.0134 alcohol consumption quality (OBA:1000840)
 PMID:30679032
GWAS1653134_H GCST90475241 Biological Father: Coronary Artery / Coronary Heart Disease 78,584 European ancestry cases, 237,084 European ancestry controls A 0.5983 2E-12 11.699 rs9349379 0.04028 family history (EFO:0000493)
coronary artery disease (EFO:0001645)
 PMID:39024449
None Available GCST90479551 Heart attack 3,961 African American or Afro-Caribbean cases, 51,544 African American or Afro-Caribbean controls, 2,384 Hispanic or Latin American cases, 26,930 Hispanic or Latin American controls, 225 East Asian ancestry cases, 3,322 East Asian ancestry controls, 39,300 European ancestry cases, 276,368 European ancestry controls A 0.6439 1E-32 32 rs9349379 0.09878 myocardial infarction (EFO:0000612)
 PMID:39024449
1 to 20 of 126 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST001347 GWAS Catalog
  GCST90018932 GWAS Catalog

Note Type Note Reference