GWAS1463556_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1463556_H (tacrolimus measurement QTL GWAS1463556 (human)) Homo sapiens

Symbol: GWAS1463556_H
Name: tacrolimus measurement QTL GWAS1463556 (human)
RGD ID: 597367482
Trait: tacrolimus measurement
LOD Score: Not Available
P Value: 4E-97
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38799,672,916 - 99,672,917RGD_MAPPER_PIPELINEGRCh38
GRCh37799,270,539 - 99,270,540RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1463556_HHumantacrolimus measurement  IAGPrs776746405850206 GWAS_CATALOGPMID:30801552

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1318498ZSCAN25zinc finger and SCAN domain containing 2579961694699738035Human
1348646CYP3A5cytochrome P450 family 3 subfamily A member 579964819499679996Human


Peak: (rs776746)
Human AssemblyChrPosition (strand)Source
GRCh38799,672,916 - 99,672,917RGD_MAPPER_PIPELINE


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597513917GWAS1609991_Hmetabolite measurement QTL GWAS1609991 (human)2e-182metabolite measurement79967291699672917Human
597481693GWAS1577767_Htacrolimus measurement QTL GWAS1577767 (human)1e-12tacrolimus measurement79967291699672917Human
597411738GWAS1507812_Hurinary metabolite measurement QTL GWAS1507812 (human)9e-30urinary metabolite measurement79967291699672917Human
597367482GWAS1463556_Htacrolimus measurement QTL GWAS1463556 (human)4e-97tacrolimus measurement79967291699672917Human
597367817GWAS1463891_Htacrolimus measurement QTL GWAS1463891 (human)5e-35tacrolimus measurement79967291699672917Human
597394152GWAS1490226_Hurinary metabolite measurement QTL GWAS1490226 (human)3e-18urinary metabolite measurement79967291699672917Human
597398079GWAS1494153_Hmetabolite measurement QTL GWAS1494153 (human)3e-52metabolite measurement79967291699672917Human
597409070GWAS1505144_Hmetabolonic lactone sulfate measurement QTL GWAS1505144 (human)2e-135metabolonic lactone sulfate measurement79967291699672917Human
597407885GWAS1503959_Hmetabolite measurement QTL GWAS1503959 (human)5e-149metabolite measurement79967291699672917Human
597530535GWAS1626609_Hlevel of oxylipin in blood plasma QTL GWAS1626609 (human)6e-34level of oxylipin in blood plasma79967291699672917Human

1 to 10 of 12 rows


1 to 13 of 13 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1463556_H GCST008577 Tacrolimus trough concentration in kidney transplant patients 1,363 European ancestry individuals, 299 African American individuals ? NR 4E-97 96.398 rs776746 0.6443 tacrolimus measurement (EFO:0008458)
 PMID:30801552
GWAS1463891_H GCST008577 Tacrolimus trough concentration in kidney transplant patients 1,363 European ancestry individuals, 299 African American individuals ? NR 5E-35 34.302 rs776746 0.4488 tacrolimus measurement (EFO:0008458)
 PMID:30801552
GWAS1490226_H GCST009735 Urinary metabolite modules (eigenmetabolites) in chronic kidney disease 1,221 cases T 0.07 3E-18 17.523 rs776746 0.015 urinary metabolite measurement (EFO:0005116)
 PMID:31959995
GWAS1494153_H GCST90266861 Plasma X-26109 levels in chronic kidney disease 3,565 European ancestry individuals T 0.03 3E-52 51.523 rs776746 0.967 metabolite measurement (EFO:0004725)
 PMID:37277652
GWAS1503959_H GCST90266691 Urine X-24353 levels in chronic kidney disease 4,843 European ancestry individuals T 0.07 5E-149 148.302 rs776746 0.804 metabolite measurement (EFO:0004725)
 PMID:37277652
GWAS1505144_H GCST90265488 Plasma metabolonic lactone sulfate levels in chronic kidney disease 4,811 European ancestry individuals T 0.06 2E-135 134.699 rs776746 1.067 metabolonic lactone sulfate measurement (EFO:0800659)
 PMID:37277652
GWAS1507812_H GCST009733 Urinary metabolite levels in chronic kidney disease 1,221 cases T 0.07 9E-30 29.046 rs776746 0.777 urinary metabolite measurement (EFO:0005116)
 PMID:31959995
GWAS1577767_H GCST90102473 Tacrolimus trough level in transplant patients (heart, kidney, lung, and liver) 287 White ancestry children, 18 Black children, 89 Asian ancestry children, 14 Aboriginal ancestry children, 47 children ? NR 1E-12 12 rs776746 1.742 tacrolimus measurement (EFO:0008458)
 PMID:33755393
GWAS1609991_H GCST90200671 X-26109 levels 6,992 European ancestry individuals C 0.957337 2E-182 181.699 rs776746 1.08999 metabolite measurement (EFO:0004725)
 PMID:36635386
GWAS1622746_H GCST90200257 Metabolonic lactone sulfate levels 8,203 European ancestry individuals C 0.936493 6E-218 217.222 rs776746 0.929459 metabolonic lactone sulfate measurement (EFO:0800659)
 PMID:36635386
GWAS1625450_H GCST90245523 X-12063 levels 14,296 European ancestry individuals T 0.065 2E-546 545.699 rs776746 0.98733866 X-12063 measurement (EFO:0021283)
 PMID:36357675
GWAS1626609_H GCST90461902 Oxylipin levels (345.2431_0.351) 11,584 Hispanic/Latino individuals ? NR 6E-34 33.222 rs776746 0.1907 level of oxylipin in blood plasma (OBA:2050338)
 PMID:39644095
GWAS1799035_H GCST90296208 Eicosanoid 11-dehydro-2,3-dinor-TXB2 b levels 1,910 African American individuals, 6,496 European ancestry individuals ? NR 4E-46 45.398 rs776746 0.35 eicosanoids measurement (EFO:0020044)
 PMID:37524825
1 to 13 of 13 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST008577 GWAS Catalog

Note Type Note Reference