GWAS1463356_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1463356_H (chronic obstructive pulmonary disease QTL GWAS1463356 (human)) Homo sapiens

Symbol: GWAS1463356_H
Name: chronic obstructive pulmonary disease QTL GWAS1463356 (human)
RGD ID: 597367282
Trait: lung integrity trait   (VT:0010906)    
LOD Score: Not Available
P Value: 6.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3866,742,916 - 6,742,917RGD_MAPPER_PIPELINEGRCh38
GRCh3766,743,149 - 6,743,150RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1463356_HHumanchronic obstructive pulmonary disease  IAGPrs1294421405850206 GWAS_CATALOGPMID:30804561

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1463356_HHumanChronic pulmonary obstruction  IAGPrs1294421405850206 GWAS_CATALOGPMID:30804561

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1463356_HHumanlung integrity trait  IAGPrs1294421405850206 GWAS_CATALOGPMID:30804561

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1463356_HHumanchronic obstructive pulmonary disease  IAGPrs1294421405850206 GWAS_CATALOGPMID:30804561

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
38645641LOC101928004uncharacterized LOC101928004666947926801171Human


Peak: (rs1294421)
Human AssemblyChrPosition (strand)Source
GRCh3866,742,916 - 6,742,917RGD_MAPPER_PIPELINE


1 to 10 of 16 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597531161GWAS1627235_HInguinal hernia QTL GWAS1627235 (human)6e-10Inguinal hernia667429166742917Human
597434552GWAS1530626_HInguinal hernia QTL GWAS1530626 (human)4e-15Inguinal hernia667429166742917Human
597418844GWAS1514918_HFEV/FVC ratio QTL GWAS1514918 (human)1e-22FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)667429166742917Human
597367282GWAS1463356_Hchronic obstructive pulmonary disease QTL GWAS1463356 (human)0.0000006lung integrity trait (VT:0010906)667429166742917Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597371031GWAS1467105_Hwaist-hip ratio QTL GWAS1467105 (human)2e-10Inguinal herniawaist to hip ratio (WHR) (CMO:0000020)667429166742917Human
597370645GWAS1466719_Hwaist-hip ratio QTL GWAS1466719 (human)2e-17waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)667429166742917Human
597355208GWAS1451282_Hwaist-hip ratio QTL GWAS1451282 (human)8e-13waist-hip ratiowaist to hip ratio (WHR) (CMO:0000020)667429166742917Human

1 to 10 of 16 rows


1 to 12 of 12 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1463356_H GCST007692 Chronic obstructive pulmonary disease 35,735 cases, 222,076 controls T 0.39 6E-7 6.222 rs1294421 1.05 chronic obstructive pulmonary disease (EFO:0000341)
 PMID:30804561
GWAS1729170_H GCST90313169 ADAM23/BSG protein level ratio 43,509 European ancestry individuals ? NR 3E-29 28.523 rs1294421 0.0780887 ADAM23/BSG protein level ratio in blood (OBA:2053684)
 PMID:38412862
GWAS1393936_H GCST004064 Waist-hip ratio up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.3801 7E-14 13.155 rs1294421 0.0255 waist-hip ratio (EFO:0004343)
 PMID:25673412
GWAS1451282_H GCST004064 Waist-hip ratio up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.3801 8E-13 12.097 rs1294421 0.0327 waist-hip ratio (EFO:0004343)
 PMID:25673412
GWAS1466719_H GCST000829 Waist-hip ratio Up to 77,167 European ancestry individuals G 0.61 2E-17 16.699 rs1294421 0.03 waist-hip ratio (EFO:0004343)
 PMID:20935629
GWAS1467105_H GCST001954 Waist-hip ratio 4,774 European ancestry high waist-to-hip ratio individuals, 5,481 European ancestry low waist-to-hip ratio individuals G 0.62 2E-10 9.699 rs1294421 1.16 waist-hip ratio (EFO:0004343)
 PMID:23563607
GWAS1514918_H GCST012495 Lung function (FEV1/FVC) 60,749 European ancestry individuals, 7,721 African ancestry individuals T 0.36786 1E-22 22 rs1294421 9.815 FEV/FVC ratio (EFO:0004713)
 PMID:30175238
None Available GCST90027168 Inguinal hernia 13,047 European ancestry cases, 262,499 European ancestry controls T 0.39 2E-10 9.699 rs1294421 1.08 Inguinal hernia (HP:0000023)
 PMID:34382107
GWAS1530626_H GCST90018868 Inguinal hernia 16,725 European ancestry cases, 428,356 European ancestry controls, 1,664 East Asian ancestry cases, 177,062 East Asian ancestry controls G NR 4E-15 14.398 rs1294421 0.0923 Inguinal hernia (HP:0000023)
 PMID:34594039
GWAS1574637_H GCST008050 Waist-hip ratio 9,140 African American females, 11,555 Hispanic/Latino females, 1,843 Asian ancestry females, 1,715 Native Hawaiian ancestry females, 585 Native American ancestry females ? NR 0.000003 5.523 rs1294421 0.04156875 waist-hip ratio (EFO:0004343)
 PMID:31217584
GWAS1574962_H GCST008052 Waist-hip ratio 10,286 African American individuals, 16,472 Hispanic/Latino individuals, 3,500 Asian ancestry individuals, 3,061 Native Hawaiian ancestry individuals, 585 Native American ancestry individuals ? NR 1E-8 8 rs1294421 0.04534542 waist-hip ratio (EFO:0004343)
 PMID:31217584
GWAS1627235_H GCST90245889 Inguinal hernia 18,791 European ancestry cases, 93,955 European ancestry controls T 0.4 6E-10 9.222 rs1294421 1.07 Inguinal hernia (HP:0000023)
 PMID:36584111
1 to 12 of 12 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST007692 GWAS Catalog

Note Type Note Reference