GWAS1439353_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1439353_H (hemoglobin measurement QTL GWAS1439353 (human)) Homo sapiens

Symbol: GWAS1439353_H
Name: hemoglobin measurement QTL GWAS1439353 (human)
RGD ID: 597343279
Trait: hemoglobin measurement
Measurement Type: hemoglobin measurement   (CMO:0000508)    
LOD Score: Not Available
P Value: 2.0E-14
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38616,287,961 - 16,287,962RGD_MAPPER_PIPELINEGRCh38
GRCh37616,288,192 - 16,288,193RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1439353_HHumanhemoglobin measurement  IAGPrs6459467405850206 GWAS_CATALOGPMID:37596262

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1439353_HHumanhemoglobin measurement  IAGPrs6459467405850206 GWAS_CATALOGPMID:37596262

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
733310GMPRguanosine monophosphate reductase61623858716295549Human


Peak: (rs6459467)
Human AssemblyChrPosition (strand)Source
GRCh38616,287,961 - 16,287,962RGD_MAPPER_PIPELINE


1 to 10 of 21 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
597343960GWAS1440034_Hhemoglobin measurement QTL GWAS1440034 (human)4e-20hemoglobin measurementhemoglobin measurement (CMO:0000508)61628796116287962Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597616692GWAS1673552_Hmean corpuscular hemoglobin concentration QTL GWAS1673552 (human)4e-52mean corpuscular hemoglobin concentrationmean corpuscular hemoglobin concentration (CMO:0000291)61628796116287962Human
406976141GWAS625117_Hmean corpuscular hemoglobin QTL GWAS625117 (human)2e-59mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)61628796116287962Human
597280265GWAS1376339_Hxanthosine measurement QTL GWAS1376339 (human)1e-18xanthosine measurement61628796116287962Human

1 to 10 of 21 rows


1 to 12 of 12 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1439353_H GCST90281207 Hyper-haemoglobinised percentage of red cells 38,553 European ancestry individuals A 0.3836 2E-14 13.699 rs6459467 0.0560767 hemoglobin measurement (EFO:0004509)
 PMID:37596262
GWAS1640297_H GCST90479671 mean corpuscular hemoglobin concentration (MCHC, minimum, inv-norm transformed) 114,841 African American or Afro-Caribbean individuals, 55,798 Hispanic or Latin American individuals, 5,943 East Asian ancestry individuals, 407,301 European ancestry individuals G 0.5079 1E-38 38 rs6459467 0.0363 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS599759_H GCST004605 Mean corpuscular hemoglobin concentration 172,851 European ancestry individuals A 0.3801 4E-27 26.398 rs6459467 0.03847969 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:27863252
GWAS1140982_H GCST010083 Hemoglobin levels 684,122 European ancestry individuals A NR 8E-21 20.097 rs6459467 0.021 hemoglobin measurement (EFO:0004509)
 PMID:32327693
GWAS625117_H GCST004630 Mean corpuscular hemoglobin 172,332 European ancestry individuals A 0.3799 2E-59 58.699 rs6459467 0.05917168 mean corpuscular hemoglobin (EFO:0004527)
 PMID:27863252
GWAS626542_H GCST004615 Hemoglobin concentration 172,925 European ancestry individuals A 0.38 3E-10 9.523 rs6459467 0.02300312 hemoglobin measurement (EFO:0004509)
 PMID:27863252
GWAS1654567_H GCST90475376 hemoglobin (mean, inv-norm transformed) 407,894 European ancestry individuals G 0.6105 2E-12 11.699 rs6459467 0.01818 hemoglobin measurement (EFO:0004509)
 PMID:39024449
GWAS1673552_H GCST90475462 mean corpuscular hemoglobin concentration (MCHC, minimum, inv-norm transformed) 407,301 European ancestry individuals G 0.6105 4E-52 51.398 rs6459467 0.0404 mean corpuscular hemoglobin concentration (EFO:0004528)
 PMID:39024449
GWAS1376339_H GCST90140235 Xanthosine levels 6,136 Finnish ancestry individuals A NR 1E-18 18 rs6459467 0.26 xanthosine measurement (EFO:0010549)
 PMID:35347128
GWAS1440034_H GCST90281217 Reticulocyte haemoglobin equivalent 39,127 European ancestry individuals A 0.3833 4E-20 19.398 rs6459467 0.0661529 hemoglobin measurement (EFO:0004509)
 PMID:37596262
GWAS1780995_H GCST90243463 Hypoxanthine levels 7,287 European ancestry individuals A 0.39 2E-16 15.699 rs6459467 0.02 hypoxanthine measurement (EFO:0010500)
 PMID:24816252
GWAS1796300_H GCST90281204 Red blood cell forward scatter 38,005 European ancestry individuals A 0.3836 1E-17 17 rs6459467 0.0622567 erythrocyte attribute (OBA:2045276)
 PMID:37596262
1 to 12 of 12 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90281207 GWAS Catalog

Note Type Note Reference