GWAS1419756_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1419756_H (schizophrenia QTL GWAS1419756 (human)) Homo sapiens

Symbol: GWAS1419756_H
Name: schizophrenia QTL GWAS1419756 (human)
RGD ID: 597323682
Trait: schizophrenia
LOD Score: Not Available
P Value: 1.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3818,362,616 - 8,362,617RGD_MAPPER_PIPELINEGRCh38
GRCh3718,422,676 - 8,422,677RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1419756_HHumanschizophrenia  IAGPrs2252865405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:35396580


#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1344336REREarginine-glutamic acid dipeptide repeats183524048817640Human


Peak: (rs2252865)
Human AssemblyChrPosition (strand)Source
GRCh3818,362,616 - 8,362,617RGD_MAPPER_PIPELINE


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597449128GWAS1545202_Hsystolic blood pressure QTL GWAS1545202 (human)4e-10systolic blood pressuresystolic blood pressure (CMO:0000004)183626168362617Human
596964098GWAS1083617_Hattention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder QTL GWAS1083617 (human)0.0000005attention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder183626168362617Human
597323682GWAS1419756_Hschizophrenia QTL GWAS1419756 (human)1e-10schizophrenia183626168362617Human
597461974GWAS1558048_Hdiastolic blood pressure QTL GWAS1558048 (human)2e-10diastolic blood pressurediastolic blood pressure (CMO:0000005)183626168362617Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
406910300GWAS559276_Hattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia QTL GWAS559276 (human)0.0000005attention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia183626168362617Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human

1 to 10 of 11 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1419756_H GCST90128471 Schizophrenia 53,386 European ancestry cases, 77,258 European ancestry controls, 14,004 East Asian ancestry cases, 16,757 East Asian ancestry controls, 6,152 African American cases, 3,918 African American controls, 1,234 Latino cases, 3,090 Latino controls T 0.277 1E-10 10 rs2252865 1.05411 PMID:35396580
GWAS1708285_H GCST004137 Optic cup area 20,353 European ancestry individuals, 2,131 Erasmus Rucphen (founder/genetic isolate) individuals T NR 6E-8 7.222 rs2252865 0.013 optic cup area (OBA:2045265)
 PMID:28073927
GWAS1708292_H GCST004137 Optic cup area 20,353 European ancestry individuals, 2,131 Erasmus Rucphen (founder/genetic isolate) individuals T NR 1E-9 9 rs2252865 0.015 optic cup area (OBA:2045265)
 PMID:28073927
GWAS1714315_H GCST005348 Total body bone mineral density 56,284 European ancestry individuals, up to 1,333 African American individuals, up to 9,328 admixed individuals T 0.3241 5E-8 7.302 rs2252865 0.0328 bone density (OBA:1000110)
 PMID:29304378
GWAS796729_H GCST001242 Schizophrenia 9,394 European ancestry cases, 12,462 European ancestry controls ? NR 0.000003 5.523 rs2252865 1.08 PMID:21926974
GWAS1083617_H GCST001877 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) 6,990 European ancestry Bipolar disorder cases, 9,227 European ancestry Major depressive disorder cases, 9,379 European ancestry Schizophrenia cases, 161 European ancestry Autism spectrum disorder cases, 4,788 European ancestry Autism spectrum disorder trio cases, 840 European ancestry Attention deficit-hyperactivity disorder cases, 1,947 European ancestry Attention defcit-hyperactivity disorder trio cases, 27,888 European ancestry controls T NR 5E-7 6.302 rs2252865 1.03 attention deficit hyperactivity disorder (EFO:0003888)
autism spectrum disorder (EFO:0003756)
 PMID:23453885
GWAS1545202_H GCST90449056 Systolic blood pressure (MTAG) at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples) T NR 4E-10 9.398 rs2252865 0.01125323 systolic blood pressure (EFO:0006335)
 PMID:39537608
GWAS1558048_H GCST90449057 Diastolic blood pressure (MTAG) at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples) T NR 2E-10 9.699 rs2252865 0.011348349 diastolic blood pressure (EFO:0006336)
 PMID:39537608
Database
Acc Id
Source(s)
GWAS Catalog GCST90128471 GWAS Catalog

Note Type Note Reference