GWAS1417925_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1417925_H (non-high density lipoprotein cholesterol measurement QTL GWAS1417925 (human)) Homo sapiens

Symbol: GWAS1417925_H
Name: non-high density lipoprotein cholesterol measurement QTL GWAS1417925 (human)
RGD ID: 597321851
Trait: non-high density lipoprotein cholesterol measurement
Measurement Type: blood non-high density lipoprotein cholesterol level   (CMO:0003967)    
serum non-high density lipoprotein cholesterol level   (CMO:0003841)    
LOD Score: Not Available
P Value: 2.0E-68
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38616,130,925 - 16,130,926RGD_MAPPER_PIPELINEGRCh38
GRCh37616,131,156 - 16,131,157RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1417925_HHumannon-high density lipoprotein cholesterol measurement  IAGPrs2235215405850206 GWAS_CATALOGPMID:34887591

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1313988MYLIPmyosin regulatory light chain interacting protein61612908616163887Human


Peak: (rs2235215)
Human AssemblyChrPosition (strand)Source
GRCh38616,130,925 - 16,130,926RGD_MAPPER_PIPELINE


1 to 10 of 26 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
407087242GWAS736218_Hlow density lipoprotein cholesterol measurement QTL GWAS736218 (human)6e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)61613092516130926Human
597290320GWAS1386394_Hfree cholesterol in small LDL measurement QTL GWAS1386394 (human)4e-14blood LDL cholesterol amount (VT:0000181)61613092516130926Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597265749GWAS1361823_Htotal cholesterol measurement QTL GWAS1361823 (human)1e-57total cholesterol measurementblood total cholesterol level (CMO:0000051)61613092516130926Human
597255625GWAS1351699_Htotal cholesterol measurement QTL GWAS1351699 (human)9e-79total cholesterol measurementblood total cholesterol level (CMO:0000051)61613092516130926Human
597288137GWAS1384211_Hcholesterol in very small VLDL measurement QTL GWAS1384211 (human)4e-10cholesterol in very small VLDL measurement 61613092516130926Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
407095316GWAS744292_Hlow density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS744292 (human)3e-26low density lipoprotein cholesterol measurement, alcohol drinkingblood low density lipoprotein cholesterol level (CMO:0000053)61613092516130926Human

1 to 10 of 26 rows


1 to 17 of 17 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1417925_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 2E-68 67.699 rs2235215 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
GWAS1123603_H GCST008086 LDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 1E-13 13 rs2235215 1.126 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS1123629_H GCST008086 LDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 4E-15 14.398 rs2235215 1.486 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS1713703_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 8E-25 24.097 rs2235215 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS1713952_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 2E-29 28.699 rs2235215 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS721548_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 1E-30 30 rs2235215 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS735358_H GCST008077 LDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals C NR 1E-10 10 rs2235215 1.624 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS736218_H GCST008077 LDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals C NR 6E-9 8.222 rs2235215 1.073 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS744292_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 3E-26 25.523 rs2235215 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS1243075_H GCST90250902 Medication use for hyperlipidemia (number of purchases) 567,671 European ancestry individuals ? NR 9E-23 22.046 rs2235215 0.012839 antihyperlipidemic drug use measurement (EFO:0803367)
 PMID:36653479
GWAS1351699_H GCST90239673 Total cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 9E-79 78.046 rs2235215 N/A total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS1361823_H GCST90239676 Total cholesterol levels 1,320,016 European ancestry individuals C 0.321101 1E-57 57 rs2235215 0.027513 total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS1368567_H GCST90239658 Low density lipoprotein cholesterol levels 1,320,016 European ancestry individuals C 0.320817 2E-76 75.699 rs2235215 0.0318004 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS1384211_H GCST90302150 Total cholesterol in very small VLDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6542 4E-10 9.398 rs2235215 0.0266 cholesterol in very small VLDL measurement (EFO:0022231)
 PMID:38448586
GWAS1385598_H GCST90302103 Sphingomyelins levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals T 0.6509 3E-10 9.523 rs2235215 0.0277 sphingomyelin measurement (EFO:0010118)
 PMID:38448586
GWAS1386394_H GCST90302095 Free cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.6538 4E-14 13.398 rs2235215 0.0324 free cholesterol in small LDL measurement (EFO:0022271)
 PMID:38448586
GWAS1419141_H GCST90239670 Non-HDL cholesterol levels 1,320,016 European ancestry individuals T 0.67976 2E-52 51.699 rs2235215 0.0311564 non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
1 to 17 of 17 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90239667 GWAS Catalog

Note Type Note Reference