GWAS1387299_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1387299_H (hypertension QTL GWAS1387299 (human)) Homo sapiens

Symbol: GWAS1387299_H
Name: hypertension QTL GWAS1387299 (human)
RGD ID: 597291225
Trait: hypertension
LOD Score: Not Available
P Value: 5.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3861,613,451 - 1,613,452RGD_MAPPER_PIPELINEGRCh38
GRCh3761,613,686 - 1,613,687RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1387299_HHumanhypertension  IAGPrs2745599405850206 GWAS_CATALOGPMID:38965376

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1387299_HHumanHypertension  IAGPrs2745599405850206 GWAS_CATALOGPMID:38965376
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1387299_HHumanhypertension  IAGPrs2745599405850206 GWAS_CATALOGPMID:38965376

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1353830FOXC1forkhead box C1616099151613897Human


Peak: (rs2745599)
Human AssemblyChrPosition (strand)Source
GRCh3861,613,451 - 1,613,452RGD_MAPPER_PIPELINE


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597291225GWAS1387299_Hhypertension QTL GWAS1387299 (human)5e-09hypertension616134511613452Human
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597110196GWAS1206270_Hsystolic blood pressure QTL GWAS1206270 (human)4e-14systolic blood pressuresystolic blood pressure (CMO:0000004)616134511613452Human
597033599GWAS1129673_Hheel bone mineral density QTL GWAS1129673 (human)2e-12heel bone mineral densitybone mineral density (CMO:0001226)616134511613452Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597424782GWAS1520856_Hsystolic blood pressure QTL GWAS1520856 (human)3e-11systolic blood pressuresystolic blood pressure (CMO:0000004)616134511613452Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
2292824PRSTS5_HProstate tumor susceptibility QTL 5 (human)Prostate tumor susceptibility6119232373Human
406937339GWAS586315_Hheel bone mineral density QTL GWAS586315 (human)6e-11heel bone mineral densitybone mineral density (CMO:0001226)616134511613452Human

1 to 10 of 13 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1387299_H GCST90309346 Hypertension (confirmatory factor analysis Factor 12) 338,391 European ancestry individuals ? NR 5E-9 8.302 rs2745599 N/A hypertension (EFO:0000537)
 PMID:38965376
GWAS1129673_H GCST006979 Heel bone mineral density 426,824 British ancestry individuals A 0.552918 2E-12 11.699 rs2745599 0.0130097 heel bone mineral density (EFO:0009270)
 PMID:30598549
GWAS586315_H GCST007066 Heel bone mineral density approximately 446,000 European ancestry individuals ? NR 6E-11 10.222 rs2745599 N/A heel bone mineral density (EFO:0009270)
 PMID:30595370
GWAS1206270_H GCST006624 Systolic blood pressure 757,601 European ancestry individuals A 0.5514 4E-14 13.398 rs2745599 0.1908 systolic blood pressure (EFO:0006335)
 PMID:30224653
GWAS761227_H GCST007067 Waist-hip ratio approximately 458,000 European ancestry individuals ? NR 9E-10 9.046 rs2745599 N/A waist-hip ratio (EFO:0004343)
 PMID:30595370
GWAS1520856_H GCST90449056 Systolic blood pressure (MTAG) at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples) G NR 3E-11 10.523 rs2745599 0.011472046 systolic blood pressure (EFO:0006335)
 PMID:39537608
Database
Acc Id
Source(s)
GWAS Catalog GCST90309346 GWAS Catalog

Note Type Note Reference