GWAS1384806_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1384806_H (free cholesterol in small LDL measurement QTL GWAS1384806 (human)) Homo sapiens

Symbol: GWAS1384806_H
Name: free cholesterol in small LDL measurement QTL GWAS1384806 (human)
RGD ID: 597288732
Trait: blood LDL cholesterol amount   (VT:0000181)    
LOD Score: Not Available
P Value: 2.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381424,412,780 - 24,412,781RGD_MAPPER_PIPELINEGRCh38
GRCh371424,881,986 - 24,881,987RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1384806_HHumanblood LDL cholesterol amount  IAGPrs36012880405850206 GWAS_CATALOGPMID:38448586

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1384806_HHumanfree cholesterol in small LDL measurement  IAGPrs36012880405850206 GWAS_CATALOGPMID:38448586

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1345252NYNRINNYN domain and retroviral integrase containing142439900324419283Human


Peak: (rs36012880)
Human AssemblyChrPosition (strand)Source
GRCh381424,412,780 - 24,412,781RGD_MAPPER_PIPELINE


1 to 10 of 24 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597284312GWAS1380386_Htotal cholesterol in IDL QTL GWAS1380386 (human)4e-10total cholesterol in IDL142441278024412781Human
597286714GWAS1382788_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS1382788 (human)5e-13cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)142441278024412781Human
406938341GWAS587317_Hhemoglobin measurement QTL GWAS587317 (human)1e-12total lipids in small LDLhemoglobin measurement (CMO:0000508)142441278024412781Human
597284829GWAS1380903_Hcholesterol:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS1380903 (human)4e-11cholesterol:total lipids ratio, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)142441278024412781Human
597290268GWAS1386342_Htotal cholesterol in small LDL QTL GWAS1386342 (human)3e-14total cholesterol in small LDL142441278024412781Human
597288732GWAS1384806_Hfree cholesterol in small LDL measurement QTL GWAS1384806 (human)2e-11blood LDL cholesterol amount (VT:0000181)142441278024412781Human
597289852GWAS1385926_Hcholesterol:total lipids ratio, cholesteryl esters:total lipids ratio QTL GWAS1385926 (human)4e-14cholesterol:total lipids ratio, cholesteryl esters:total lipids ratio142441278024412781Human
597285342GWAS1381416_Hesterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS1381416 (human)8e-15esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)142441278024412781Human
597285054GWAS1381128_Hphospholipids in IDL measurement QTL GWAS1381128 (human)1e-10phospholipids in IDL measurementblood intermediate density lipoprotein phospholipid level (CMO:0001574)142441278024412781Human
597279250GWAS1375324_Hlow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio QTL GWAS1375324 (human)1e-11total lipids in large LDLblood low density lipoprotein cholesterol level (CMO:0000053)142441278024412781Human

1 to 10 of 24 rows


1 to 20 of 34 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1384806_H GCST90302095 Free cholesterol in small LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5538 2E-11 10.699 rs36012880 0.0268 free cholesterol in small LDL measurement (EFO:0022271)
 PMID:38448586
GWAS587317_H GCST90002310 Hemoglobin concentration 563,946 European ancestry individuals C 0.474437 1E-12 12 rs36012880 0.013214 hemoglobin measurement (EFO:0004509)
 PMID:32888493
GWAS627938_H GCST90002314 Hemoglobin concentration 746,431 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals C 0.379216 7E-10 9.155 rs36012880 N/A hemoglobin measurement (EFO:0004509)
 PMID:32888493
GWAS628220_H GCST90002384 Hemoglobin 408,112 British individuals C 0.476547 1E-9 9 rs36012880 0.01356346 hemoglobin measurement (EFO:0004509)
 PMID:32888494
GWAS1374656_H GCST90301979 Free cholesterol in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5539 5E-11 10.302 rs36012880 0.0262 free cholesterol in IDL measurement (EFO:0022181)
 PMID:38448586
GWAS1374832_H GCST90302050 Concentration of medium LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5542 2E-12 11.699 rs36012880 0.0281 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
GWAS1375324_H GCST90302010 Cholesteryl esters to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5541 1E-11 11 rs36012880 0.027 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
GWAS1378355_H GCST90302049 Total lipid levels in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5542 8E-13 12.097 rs36012880 0.0286 low density lipoprotein cholesterol measurement (EFO:0004611)
lipid measurement (EFO:0004529)
 PMID:38448586
GWAS1378487_H GCST90302014 Concentration of large LDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5541 3E-11 10.523 rs36012880 0.0265 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
None Available GCST90301982 Concentration of IDL particles 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5538 1E-9 9 rs36012880 0.0243 intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
None Available GCST90302009 Cholesterol esters in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5542 2E-12 11.699 rs36012880 0.0282 cholesterol esters in large LDL measurement (EFO:0022165)
 PMID:38448586
None Available GCST90302013 Total lipids in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5541 1E-11 11 rs36012880 0.027 total lipids in large LDL (EFO:0022163)
 PMID:38448586
GWAS1379169_H GCST90302044 Total cholesterol to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5537 9E-13 12.046 rs36012880 0.0284 cholesterol:total lipids ratio (EFO:0020943)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:38448586
None Available GCST90301977 Cholesterol esters in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5538 1E-9 9 rs36012880 0.0242 esterified cholesterol measurement (EFO:0008589)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:38448586
None Available GCST90302007 Total cholesterol in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5541 2E-12 11.699 rs36012880 0.0281 total cholesterol in large LDL (EFO:0022167)
 PMID:38448586
None Available GCST90302015 Phospholipids in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5541 3E-11 10.523 rs36012880 0.0266 phospholipids in large LDL measurement (EFO:0022174)
 PMID:38448586
GWAS1379373_H GCST90301981 Total lipids in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5538 6E-10 9.222 rs36012880 0.0247 total lipids in IDL (EFO:0022161)
 PMID:38448586
GWAS1379415_H GCST90302046 Cholesteryl esters to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5538 1E-13 13 rs36012880 0.0295 low density lipoprotein cholesterol measurement (EFO:0004611)
cholesteryl esters:total lipids ratio (EFO:0020944)
 PMID:38448586
GWAS1379542_H GCST90302045 Cholesterol esters in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5543 2E-14 13.699 rs36012880 0.0308 cholesterol esters in medium LDL measurement (EFO:0022186)
 PMID:38448586
GWAS1380386_H GCST90301975 Total Cholesterol in IDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.5538 4E-10 9.398 rs36012880 0.0249 total cholesterol in IDL (EFO:0022184)
 PMID:38448586
1 to 20 of 34 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90302095 GWAS Catalog

Note Type Note Reference