GWAS1380956_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1380956_H (hemoglobin measurement QTL GWAS1380956 (human)) Homo sapiens

Symbol: GWAS1380956_H
Name: hemoglobin measurement QTL GWAS1380956 (human)
RGD ID: 597284882
Trait: hemoglobin measurement
Measurement Type: hemoglobin measurement   (CMO:0000508)    
LOD Score: Not Available
P Value: 4.0E-27
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3862,050,557 - 2,050,558RGD_MAPPER_PIPELINEGRCh38
GRCh3762,050,791 - 2,050,792RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1380956_HHumanhemoglobin measurement  IAGPrs115986297405850206 GWAS_CATALOGPMID:34594039

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1380956_HHumanhemoglobin measurement  IAGPrs115986297405850206 GWAS_CATALOGPMID:34594039

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1322234GMDSGDP-mannose 4,6-dehydratase616238062245605Human


Peak: (rs115986297)
Human AssemblyChrPosition (strand)Source
GRCh3862,050,557 - 2,050,558RGD_MAPPER_PIPELINE


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597043473GWAS1139547_Hhemoglobin measurement QTL GWAS1139547 (human)2e-22hemoglobin measurementhemoglobin measurement (CMO:0000508)620505572050558Human
597025052GWAS1121126_Herythrocyte count QTL GWAS1121126 (human)6e-19erythrocyte countred blood cell count (CMO:0000025)620505572050558Human
596960093GWAS1079612_Hglomerular filtration rate QTL GWAS1079612 (human)3e-18glomerular filtration rate620505572050558Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597284882GWAS1380956_Hhemoglobin measurement QTL GWAS1380956 (human)4e-27hemoglobin measurementhemoglobin measurement (CMO:0000508)620505572050558Human
406939025GWAS588001_Hhemoglobin measurement QTL GWAS588001 (human)2e-38hemoglobin measurementhemoglobin measurement (CMO:0000508)620505572050558Human
406983251GWAS632227_Hhemoglobin measurement QTL GWAS632227 (human)1e-33erythrocyte countred blood cell count (CMO:0000025)620505572050558Human
597042831GWAS1138905_Herythrocyte count QTL GWAS1138905 (human)1e-30erythrocyte countred blood cell count (CMO:0000025)620505572050558Human
596959119GWAS1078638_Hglomerular filtration rate QTL GWAS1078638 (human)0.0000007glomerular filtration rate620505572050558Human

1 to 10 of 25 rows


1 to 20 of 22 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1380956_H GCST90018957 Hemoglobin 350,474 European ancestry individuals, 152,447 East Asian ancestry individuals G NR 4E-27 26.398 rs115986297 0.0179 hemoglobin measurement (EFO:0004509)
 PMID:34594039
GWAS1121126_H GCST004601 Red blood cell count 172,952 European ancestry individuals G 0.5428 6E-19 18.222 rs115986297 0.03173454 erythrocyte count (EFO:0004305)
 PMID:27863252
GWAS588001_H GCST90002310 Hemoglobin concentration 563,946 European ancestry individuals G 0.544482 2E-38 37.699 rs115986297 0.023977 hemoglobin measurement (EFO:0004509)
 PMID:32888493
GWAS1138905_H GCST007069 Red blood cell count approximately 445,000 European ancestry individuals ? NR 1E-30 30 rs115986297 N/A erythrocyte count (EFO:0004305)
 PMID:30595370
GWAS1139547_H GCST010083 Hemoglobin levels 684,122 European ancestry individuals A NR 2E-22 21.699 rs115986297 0.021 hemoglobin measurement (EFO:0004509)
 PMID:32327693
GWAS603205_H GCST004604 Hematocrit 173,039 European ancestry individuals G 0.5429 1E-17 17 rs115986297 0.03036389 hematocrit (EFO:0004348)
 PMID:27863252
GWAS1148141_H GCST90002304 Hematocrit 562,259 European ancestry individuals G 0.544425 1E-44 44 rs115986297 0.025952 hematocrit (EFO:0004348)
 PMID:32888493
GWAS626541_H GCST004615 Hemoglobin concentration 172,925 European ancestry individuals G 0.5429 7E-15 14.155 rs115986297 0.02773504 hemoglobin measurement (EFO:0004509)
 PMID:27863252
GWAS627402_H GCST90002383 Hematocrit 408,112 British individuals G 0.543385 3E-36 35.523 rs115986297 0.02778851 hematocrit (EFO:0004348)
 PMID:32888494
GWAS632227_H GCST90002384 Hemoglobin 408,112 British individuals G 0.543401 1E-33 33 rs115986297 0.026719721 hemoglobin measurement (EFO:0004509)
 PMID:32888494
None Available GCST90002403 Red blood cell count 408,112 British individuals G 0.543376 1E-33 33 rs115986297 0.026391655 erythrocyte count (EFO:0004305)
 PMID:32888494
GWAS1734113_H GCST90002363 Red blood cell count 545,203 European ancestry individuals G 0.544245 1E-42 42 rs115986297 0.025232 red blood cell density (OBA:2045260)
 PMID:32888493
GWAS1734943_H GCST90002367 Red blood cell count 727,624 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals G 0.575411 2E-41 40.699 rs115986297 N/A red blood cell density (OBA:2045260)
 PMID:32888493
GWAS1393160_H GCST90018960 Hematocrit 350,475 European ancestry individuals, 153,015 East Asian ancestry individuals G NR 1E-26 26 rs115986297 0.0181 hematocrit (EFO:0004348)
 PMID:34594039
GWAS1404613_H GCST90018971 Red blood cell count 350,475 European ancestry individuals, 153,512 East Asian ancestry individuals G NR 2E-27 26.699 rs115986297 0.0191 erythrocyte count (EFO:0004305)
 PMID:34594039
GWAS1442107_H GCST90319906 Serum urate levels 677,373 European ancestry individuals A NR 9E-14 13.046 rs115986297 0.0202 urate measurement (EFO:0004531)
 PMID:38658550
GWAS1443729_H GCST90319904 Serum urate levels 219,768 East Asian ancestry individuals, 677,373 European ancestry individuals, 132,182 individuals A NR 3E-20 19.523 rs115986297 0.0203 urate measurement (EFO:0004531)
 PMID:38658550
GWAS1522373_H GCST90455669 Serum urate levels 630,117 European ancestry individuals A 0.455 2E-17 16.699 rs115986297 0.0195 urate measurement (EFO:0004531)
 PMID:39406924
GWAS1523506_H GCST90455676 Gout 100,671 European ancestry cases, 2,106,212 European ancestry controls A 0.453 4E-8 7.398 rs115986297 1.0278816 gout (EFO:0004274)
 PMID:39406924
GWAS1804492_H GCST90428448 Estimated glomerular filtration rate (cystatin c) 406,504 European ancestry individuals G NR 1E-19 19 rs115986297 0.0185773 glomerular filtration rate (OBA:0003747)
 PMID:39256582
1 to 20 of 22 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90018957 GWAS Catalog

Note Type Note Reference