GWAS1365919_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1365919_H (rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement QTL GWAS1365919 (human)) Homo sapiens

Symbol: GWAS1365919_H
Name: rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement QTL GWAS1365919 (human)
RGD ID: 597269845
Trait: rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement
LOD Score: Not Available
P Value: 3.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3812,800,059 - 2,800,060RGD_MAPPER_PIPELINEGRCh38
GRCh3712,716,624 - 2,716,625RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1365919_HHumanrheumatoid arthritis  IAGPrs897628405850206 GWAS_CATALOGPMID:35470158

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1365919_HHumanRheumatoid arthritis  IAGPrs897628405850206 GWAS_CATALOGPMID:35470158

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
2293894TTC34tetratricopeptide repeat domain 34126369862801693Human


Peak: (rs897628)
Human AssemblyChrPosition (strand)Source
GRCh3812,800,059 - 2,800,060RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597269845GWAS1365919_Hrheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement QTL GWAS1365919 (human)3e-16rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement128000592800060Human
597267476GWAS1363550_Hrheumatoid arthritis QTL GWAS1363550 (human)2e-10rheumatoid arthritis128000592800060Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1365919_H GCST90131438 Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) 14,551 European ancestry cases, 846,260 European ancestry controls, 3,468 cases, 145,344 controls T 0.3362 3E-16 15.523 rs897628 0.9 rheumatoid arthritis (EFO:0000685)
ACPA-positive rheumatoid arthritis (EFO:0009459)
rheumatoid factor seropositivity measurement (EFO:0007791)
 PMID:35470158
GWAS1363550_H GCST90131437 Rheumatoid arthritis 26,612 European ancestry cases, 869,454 European ancestry controls, 4,701 cases, 125,923 controls T 0.3362 2E-10 9.699 rs897628 0.94 rheumatoid arthritis (EFO:0000685)
 PMID:35470158
Database
Acc Id
Source(s)
GWAS Catalog GCST90131438 GWAS Catalog

Note Type Note Reference