GWAS1365451_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1365451_H (BMI-adjusted waist circumference QTL GWAS1365451 (human)) Homo sapiens

Symbol: GWAS1365451_H
Name: BMI-adjusted waist circumference QTL GWAS1365451 (human)
RGD ID: 597269377
Trait: body size trait   (VT:0100005)    
LOD Score: Not Available
P Value: 6.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38975,895,907 - 75,895,908RGD_MAPPER_PIPELINEGRCh38
GRCh37978,510,823 - 78,510,824RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1365451_HHumanbody size trait  IAGPrs35344761405850206 GWAS_CATALOGPMID:34021172

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1365451_HHumanBMI-adjusted waist circumference  IAGPrs35344761405850206 GWAS_CATALOGPMID:34021172

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
732125PCSK5proprotein convertase subtilisin/kexin type 597588980976362975Human


Peak: (rs35344761)
Human AssemblyChrPosition (strand)Source
GRCh38975,895,907 - 75,895,908RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597060135GWAS1156209_HBMI-adjusted waist circumference QTL GWAS1156209 (human)2e-33body size trait (VT:0100005)97589590775895908Human
597051349GWAS1147423_Hbody fat distribution QTL GWAS1147423 (human)2e-31body fat distributionbody fat morphological measurement (CMO:0000089)97589590775895908Human
597043696GWAS1139770_Hbody fat distribution QTL GWAS1139770 (human)2e-20body fat distributionbody fat morphological measurement (CMO:0000089)97589590775895908Human
597269377GWAS1365451_HBMI-adjusted waist circumference QTL GWAS1365451 (human)6e-09body size trait (VT:0100005)97589590775895908Human
597221808GWAS1317882_HBMI-adjusted waist circumference QTL GWAS1317882 (human)3e-21body size trait (VT:0100005)97589590775895908Human
597051404GWAS1147478_Hbody fat distribution QTL GWAS1147478 (human)8e-24body fat distributionbody fat morphological measurement (CMO:0000089)97589590775895908Human
597043917GWAS1139991_Hbody fat distribution QTL GWAS1139991 (human)5e-27body fat distributionbody fat morphological measurement (CMO:0000089)97589590775895908Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1365451_H GCST012231 A body shape index 186,825 British ancestry men A NR 6E-9 8.222 rs35344761 0.027784 BMI-adjusted waist circumference (EFO:0007789)
 PMID:34021172
GWAS1709645_H GCST008163 Height 1,249 whole genome sequenced European ancestry individuals, 3,541 whole genome sequenced individuals, 46,910 European ancestry individuals, 471 Carlantino (founder/genetic isolate) individuals, 1,197 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,043 Mylopotamos (founder/genetic isolate) individuals, 933 Pomak (founder/genetic isolate) individuals, 1,785 Val Borbera (founder/genetic isolate) individuals A 0.126 0.000001 6 rs35344761 0.0519 body height (OBA:VT0001253)
 PMID:28552196
GWAS1139770_H GCST007295 Body fat distribution (leg fat ratio) 55,006 British ancestry males, 61,132 British ancestry females A 0.119004 2E-20 19.699 rs35344761 0.0335 body fat distribution (EFO:0004341)
 PMID:30664634
GWAS1139991_H GCST007295 Body fat distribution (leg fat ratio) 55,006 British ancestry males, 61,132 British ancestry females A 0.119004 5E-27 26.302 rs35344761 0.05599 body fat distribution (EFO:0004341)
 PMID:30664634
GWAS1147423_H GCST007294 Body fat distribution (trunk fat ratio) 55,006 British ancestry males, 61,132 British ancestry females A 0.119004 2E-31 30.699 rs35344761 0.06166 body fat distribution (EFO:0004341)
 PMID:30664634
GWAS1147478_H GCST007294 Body fat distribution (trunk fat ratio) 55,006 British ancestry males, 61,132 British ancestry females A 0.119004 8E-24 23.097 rs35344761 0.03798 body fat distribution (EFO:0004341)
 PMID:30664634
GWAS1156209_H GCST009867 Waist circumference adjusted for body mass index 457,690 European ancestry individuals ? NR 2E-33 32.699 rs35344761 N/A BMI-adjusted waist circumference (EFO:0007789)
 PMID:31669095
GWAS1317882_H GCST012226 Waist circumference adjusted for body mass index 186,825 British ancestry men A NR 3E-21 20.523 rs35344761 0.0449717 BMI-adjusted waist circumference (EFO:0007789)
 PMID:34021172
Database
Acc Id
Source(s)
GWAS Catalog GCST012231 GWAS Catalog

Note Type Note Reference