GWAS1350594_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1350594_H (alkaline phosphatase measurement QTL GWAS1350594 (human)) Homo sapiens

Symbol: GWAS1350594_H
Name: alkaline phosphatase measurement QTL GWAS1350594 (human)
RGD ID: 597254520
Trait: alkaline phosphatase measurement
Measurement Type: blood alkaline phosphatase activity level   (CMO:0000576)    
LOD Score: Not Available
P Value: 3E-154
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38121,573,683 - 21,573,684RGD_MAPPER_PIPELINEGRCh38
GRCh37121,900,176 - 21,900,177RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1350594_HHumanblood alkaline phosphatase activity level  IAGPrs121918002405850206 GWAS_CATALOGPMID:33462484

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1350594_HHumanalkaline phosphatase measurement  IAGPrs121918002405850206 GWAS_CATALOGPMID:33462484

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1346147ALPLalkaline phosphatase, biomineralization associated12150898421578410Human


Peak: (rs121918002)
Human AssemblyChrPosition (strand)Source
GRCh38121,573,683 - 21,573,684RGD_MAPPER_PIPELINE


1 to 9 of 9 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597254520GWAS1350594_Halkaline phosphatase measurement QTL GWAS1350594 (human)3e-154alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)12157368321573684Human
597119285GWAS1215359_Hblood phosphate measurement QTL GWAS1215359 (human)5e-38blood phosphate amount (VT:0001565)blood phosphate level (CMO:0000504)12157368321573684Human
597243565GWAS1339639_Hblood phosphate measurement QTL GWAS1339639 (human)3e-23blood phosphate amount (VT:0001565)blood phosphate level (CMO:0000504)12157368321573684Human
597119857GWAS1215931_Halkaline phosphatase measurement QTL GWAS1215931 (human)8e-296alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)12157368321573684Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human

1 to 9 of 9 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1350594_H GCST90019494 Serum alkaline phosphatase levels 342,535 European ancestry individuals, 6,019 African ancestry individuals, 7,337 South Asian ancestry individuals C NR 3E-154 153.523 rs121918002 2.3272 alkaline phosphatase measurement (EFO:0004533)
 PMID:33462484
GWAS1215359_H GCST90025948 Serum phosphate levels 400,159 European ancestry individuals ? NR 5E-38 37.302 rs121918002 0.976458 blood phosphate measurement (EFO:0010972)
 PMID:34226706
GWAS1215931_H GCST90025947 Serum alkaline phosphatase levels 437,896 European ancestry individuals ? NR 8E-296 295.097 rs121918002 2.40873 alkaline phosphatase measurement (EFO:0004533)
 PMID:34226706
GWAS1339639_H GCST90019516 Serum phosphate levels 312,888 European ancestry individuals, 5,568 African ancestry individuals, 6,685 South Asian ancestry individuals C NR 3E-23 22.523 rs121918002 0.9251 blood phosphate measurement (EFO:0010972)
 PMID:33462484
Database
Acc Id
Source(s)
GWAS Catalog GCST90019494 GWAS Catalog

Note Type Note Reference