GWAS1280893_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1280893_H (vital capacity QTL GWAS1280893 (human)) Homo sapiens

Symbol: GWAS1280893_H
Name: vital capacity QTL GWAS1280893 (human)
RGD ID: 597184819
Trait: vital capacity
LOD Score: Not Available
P Value: 4.0E-51
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38116,979,534 - 16,979,535RGD_MAPPER_PIPELINEGRCh38
GRCh37117,306,029 - 17,306,030RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1280893_HHumanvital capacity  IAGPrs9435731405850206 GWAS_CATALOGPMID:36641522

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1314413MFAP2microfibril associated protein 211697450216981583Human
155632733LOC127267744H3K4me1 hESC enhancer GRCh37_chr1:17305891-1730639611697939616979901Human


Peak: (rs9435731)
Human AssemblyChrPosition (strand)Source
GRCh38116,979,534 - 16,979,535RGD_MAPPER_PIPELINE


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407252102GWAS901078_Hchronic obstructive pulmonary disease QTL GWAS901078 (human)7e-10lung integrity trait (VT:0010906)11697953416979535Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597143765GWAS1239839_Hchronic obstructive pulmonary disease QTL GWAS1239839 (human)3e-11lung integrity trait (VT:0010906)11697953416979535Human
597186431GWAS1282505_Hforced expiratory volume QTL GWAS1282505 (human)1e-13forced expiratory volumeforced expiratory volume (CMO:0000254)11697953416979535Human
597184819GWAS1280893_Hvital capacity QTL GWAS1280893 (human)4e-51vital capacity11697953416979535Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
597346231GWAS1442305_HFEV/FVC ratio QTL GWAS1442305 (human)1e-70FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)11697953416979535Human

1 to 10 of 11 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1280893_H GCST90270083 FVC 383,471 European ancestry individuals ? NR 4E-51 50.398 rs9435731 N/A vital capacity (EFO:0004312)
 PMID:36641522
GWAS1730344_H GCST90314487 DKK3/LTBP2 protein level ratio 43,509 European ancestry individuals ? NR 9E-59 58.046 rs9435731 0.103476 DKK3/LTBP2 protein level ratio in blood (OBA:2053621)
 PMID:38412862
GWAS1239839_H GCST90244098 Chronic obstructive pulmonary disease liability (machine learning-based score) 325,027 European ancestry individuals C NR 3E-11 10.523 rs9435731 0.013624 chronic obstructive pulmonary disease (EFO:0000341)
 PMID:37069358
GWAS1282505_H GCST90270081 FEV1 383,471 European ancestry individuals ? NR 1E-13 13 rs9435731 N/A forced expiratory volume (EFO:0004314)
 PMID:36641522
GWAS1293007_H GCST90278629 FVC 62,901 Taiwanese ancestry individuals ? NR 6E-18 17.222 rs9435731 N/A vital capacity (EFO:0004312)
 PMID:38116116
GWAS901078_H GCST007692 Chronic obstructive pulmonary disease 35,735 cases, 222,076 controls A 0.51 7E-10 9.155 rs9435731 1.06 chronic obstructive pulmonary disease (EFO:0000341)
 PMID:30804561
GWAS1442305_H GCST90244094 Lung function (FEV1/FVC) 475,645 European ancestry individuals, 8,590 African ancestry individuals, 85,279 East Asian ancestry individuals, 4,270 South Asian ancestry individuals, 14,668 Hispanic or Latin American individuals A 0.475 1E-70 70 rs9435731 17.774 FEV/FVC ratio (EFO:0004713)
 PMID:36914875
GWAS1808973_H GCST90018959 Height 360,388 European ancestry individuals, 165,056 East Asian ancestry individuals A NR 4E-100 99.398 rs9435731 0.0278 body height (OBA:VT0001253)
 PMID:34594039
Database
Acc Id
Source(s)
GWAS Catalog GCST90270083 GWAS Catalog

Note Type Note Reference