GWAS1263561_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1263561_H (alkaline phosphatase measurement QTL GWAS1263561 (human)) Homo sapiens

Symbol: GWAS1263561_H
Name: alkaline phosphatase measurement QTL GWAS1263561 (human)
RGD ID: 597167487
Trait: alkaline phosphatase measurement
Measurement Type: blood alkaline phosphatase activity level   (CMO:0000576)    
LOD Score: Not Available
P Value: 8.0E-41
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381424,403,003 - 24,403,004RGD_MAPPER_PIPELINEGRCh38
GRCh371424,872,209 - 24,872,210RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1263561_HHumanblood alkaline phosphatase activity level  IAGPrs6573778405850206 GWAS_CATALOGPMID:34594039

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1263561_HHumanalkaline phosphatase measurement  IAGPrs6573778405850206 GWAS_CATALOGPMID:34594039

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1345252NYNRINNYN domain and retroviral integrase containing142439900324419283Human


Peak: (rs6573778)
Human AssemblyChrPosition (strand)Source
GRCh381424,403,003 - 24,403,004RGD_MAPPER_PIPELINE


1 to 10 of 14 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597324281GWAS1420355_Hnon-high density lipoprotein cholesterol measurement QTL GWAS1420355 (human)3e-41non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)142440300324403004Human
407087239GWAS736215_Hlow density lipoprotein cholesterol measurement QTL GWAS736215 (human)3e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)142440300324403004Human
597167487GWAS1263561_Halkaline phosphatase measurement QTL GWAS1263561 (human)8e-41alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)142440300324403004Human
597155664GWAS1251738_Htriglyceride measurement, intermediate density lipoprotein measurement QTL GWAS1251738 (human)3e-08triglyceride measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)142440300324403004Human
597284691GWAS1380765_Hhistidine measurement QTL GWAS1380765 (human)5e-17histidine measurementblood amino acid measurement (CMO:0003730)142440300324403004Human
407073032GWAS722008_Hlow density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS722008 (human)4e-14low density lipoprotein cholesterol measurement, alcohol drinkingblood low density lipoprotein cholesterol level (CMO:0000053)142440300324403004Human
597285970GWAS1382044_Hlow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS1382044 (human)2e-14low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)142440300324403004Human
597051622GWAS1147696_Hlow density lipoprotein cholesterol measurement, physical activity QTL GWAS1147696 (human)2e-13low density lipoprotein cholesterol measurement, alcohol consumption measurementblood low density lipoprotein cholesterol level (CMO:0000053)142440300324403004Human
597149829GWAS1245903_Htriglyceride measurement, low density lipoprotein cholesterol measurement QTL GWAS1245903 (human)6e-11triglyceride measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)142440300324403004Human
597027116GWAS1123190_Hlow density lipoprotein cholesterol measurement QTL GWAS1123190 (human)1e-12low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)142440300324403004Human

1 to 10 of 14 rows


1 to 18 of 18 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1263561_H GCST90018942 Serum alkaline phosphatase levels 344,292 European ancestry individuals, 118,886 East Asian ancestry individuals C NR 8E-41 40.097 rs6573778 0.0301 alkaline phosphatase measurement (EFO:0004533)
 PMID:34594039
GWAS1123161_H GCST008086 LDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 6E-8 7.222 rs6573778 1.05 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS1123190_H GCST008086 LDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 1E-12 12 rs6573778 1.197 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS1147696_H GCST007284 LDL cholesterol x physical activity interaction (2df test) 7,260 African American inactive individuals, 12,761 African American active individuals, 2,740 Asian ancestry inactive individuals, 3,615 Asian ancestry active individuals, 22,378 European ancestry inactive individuals, 55,310 European ancestry active individuals, 2,163 Hispanic or Latin American inactive individuals, 3,461 Hispanic or Latin American active individuals T 0.4152 2E-13 12.699 rs6573778 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
physical activity (EFO:0003940)
 PMID:30670697
GWAS1713671_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 0.000009 5.046 rs6573778 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS1713683_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 2E-19 18.699 rs6573778 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
None Available GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 2E-13 12.699 rs6573778 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS722008_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 4E-14 13.398 rs6573778 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS736215_H GCST008077 LDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals C NR 3E-9 8.523 rs6573778 1.253 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS743982_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 6E-21 20.222 rs6573778 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS1245903_H GCST90092866 Triglyceride levels in large LDL 115,082 European ancestry individuals T 0.482664 6E-11 10.222 rs6573778 0.0265302 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1251738_H GCST90092841 Triglyceride levels in IDL 115,082 European ancestry individuals T 0.482664 3E-8 7.523 rs6573778 0.0223836 triglyceride measurement (EFO:0004530)
intermediate density lipoprotein measurement (EFO:0008595)
 PMID:35213538
GWAS1348266_H GCST90019498 Aspartate aminotransferase to alanine aminotransferase ratio 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals C NR 2E-10 9.699 rs6573778 0.0152 aspartate aminotransferase to alanine aminotransferase ratio (EFO:0010934)
 PMID:33462484
None Available GCST90019499 C-reactive protein levels 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals C NR 2E-10 9.699 rs6573778 0.0153 C-reactive protein measurement (EFO:0004458)
 PMID:33462484
GWAS1379409_H GCST90302016 Phospholipids to total lipids ratio in large LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.45 6E-10 9.222 rs6573778 0.0248 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS1380765_H GCST90301974 Histidine levels 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.4493 5E-17 16.302 rs6573778 0.034 histidine measurement (EFO:0009769)
 PMID:38448586
GWAS1382044_H GCST90302052 Phospholipids to total lipids ratio in medium LDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals T 0.4504 2E-14 13.699 rs6573778 0.0305 low density lipoprotein cholesterol measurement (EFO:0004611)
phospholipids:total lipids ratio (EFO:0020946)
 PMID:38448586
GWAS1420355_H GCST90239667 Non-HDL cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-41 40.523 rs6573778 N/A non-high density lipoprotein cholesterol measurement (EFO:0005689)
 PMID:34887591
1 to 18 of 18 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90018942 GWAS Catalog

Note Type Note Reference