GWAS1261303_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1261303_H (triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS1261303 (human)) Homo sapiens

Symbol: GWAS1261303_H
Name: triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement QTL GWAS1261303 (human)
RGD ID: 597165229
Trait: triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 8.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386161,238,337 - 161,238,338RGD_MAPPER_PIPELINEGRCh38
GRCh376161,659,369 - 161,659,370RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1261303_HHumanblood low density lipoprotein cholesterol level  IAGPrs148349043405850206 GWAS_CATALOGPMID:35213538

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1261303_HHumanlow density lipoprotein cholesterol measurement  IAGPrs148349043405850206 GWAS_CATALOGPMID:35213538
GWAS1261303_HHumantriglycerides:total lipids ratio  IAGPrs148349043405850206 GWAS_CATALOGPMID:35213538

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1354001AGPAT41-acylglycerol-3-phosphate O-acyltransferase 46161129967161274061Human


Peak: (rs148349043)
Human AssemblyChrPosition (strand)Source
GRCh386161,238,337 - 161,238,338RGD_MAPPER_PIPELINE


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597266009GWAS1362083_Hlow density lipoprotein cholesterol measurement QTL GWAS1362083 (human)3e-41low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
597153206GWAS1249280_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS1249280 (human)2e-14low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
597263356GWAS1359430_Htriglyceride measurement, high density lipoprotein cholesterol measurement QTL GWAS1359430 (human)3e-10triglyceride measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)6161238337161238338Human
597166237GWAS1262311_Htriglyceride measurement QTL GWAS1262311 (human)3e-20non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)6161238337161238338Human
597288958GWAS1385032_Hangina pectoris QTL GWAS1385032 (human)2e-09angina pectoris6161238337161238338Human
597156912GWAS1252986_Hfatty acid measurement QTL GWAS1252986 (human)5e-08fatty acid measurement6161238337161238338Human
597285425GWAS1381499_Hcardiovascular disease QTL GWAS1381499 (human)5e-09cardiovascular disease6161238337161238338Human
597259984GWAS1356058_Hlow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS1356058 (human)7e-16low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood low density lipoprotein cholesterol level (CMO:0000053)6161238337161238338Human
597326771GWAS1422845_Hnon-high density lipoprotein cholesterol measurement QTL GWAS1422845 (human)4e-24non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)6161238337161238338Human
597265035GWAS1361109_Htotal cholesterol measurement QTL GWAS1361109 (human)6e-23total cholesterol measurementblood total cholesterol level (CMO:0000051)6161238337161238338Human

1 to 10 of 18 rows


1 to 20 of 27 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1261303_H GCST90092967 Triglycerides to total lipids ratio in small LDL 115,082 European ancestry individuals C 0.986456 8E-12 11.097 rs148349043 0.12558 triglycerides:total lipids ratio (EFO:0020947)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1249280_H GCST90092909 Free cholesterol to total lipids ratio in medium LDL 115,082 European ancestry individuals C 0.986456 2E-14 13.699 rs148349043 0.139585 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS1252986_H GCST90092935 Ratio of omega-6 fatty acids to total fatty acids 115,006 European ancestry individuals C 0.986455 5E-8 7.302 rs148349043 0.100068 fatty acid measurement (EFO:0005110)
 PMID:35213538
GWAS1262219_H GCST90092966 Triglyceride levels in small LDL 115,082 European ancestry individuals C 0.986456 1E-20 20 rs148349043 0.172114 triglyceride measurement (EFO:0004530)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:35213538
GWAS1262311_H GCST90092992 Total triglycerides levels 115,082 European ancestry individuals C 0.986456 3E-20 19.523 rs148349043 0.169475 triglyceride measurement (EFO:0004530)
 PMID:35213538
GWAS1748624_H GCST90093051 Triglycerides to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 3E-26 25.523 rs148349043 0.205718 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1749003_H GCST90093027 Triglycerides to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.9865120000000001 2E-17 16.699 rs148349043 0.156819 triglycerides:total lipids ratio (EFO:0020947)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1757206_H GCST90093021 Free cholesterol to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.9865120000000001 2E-10 9.699 rs148349043 0.117704 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1757271_H GCST90093019 Cholesteryl esters to total lipids ratio in very large VLDL 114,160 European ancestry individuals C 0.9865120000000001 9E-25 24.046 rs148349043 0.187873 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1757761_H GCST90093043 Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 2E-18 17.699 rs148349043 0.170072 cholesteryl esters:total lipids ratio (EFO:0020944)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1757809_H GCST90093041 Cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 3E-25 24.523 rs148349043 0.20013 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1352849_H GCST90239673 Total cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 7E-30 29.155 rs148349043 N/A total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS1758910_H GCST90093045 Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL 111,638 European ancestry individuals C 0.986698 1E-28 28 rs148349043 0.213258 free cholesterol:total lipids ratio (EFO:0020945)
blood VLDL cholesterol amount (OBA:VT0005144)
chylomicron amount (OBA:2050296)
 PMID:35213538
GWAS1356058_H GCST90092961 Free cholesterol to total lipids ratio in small LDL 115,082 European ancestry individuals C 0.986456 7E-16 15.155 rs148349043 0.148535 low density lipoprotein cholesterol measurement (EFO:0004611)
free cholesterol:total lipids ratio (EFO:0020945)
 PMID:35213538
GWAS1759373_H GCST90092869 Cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals C 0.986455 6E-16 15.222 rs148349043 0.15092 cholesterol:total lipids ratio (EFO:0020943)
blood VLDL cholesterol amount (OBA:VT0005144)
 PMID:35213538
GWAS1359430_H GCST90093014 Triglyceride levels in very large HDL 115,082 European ancestry individuals C 0.986456 3E-10 9.523 rs148349043 0.117643 triglyceride measurement (EFO:0004530)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:35213538
GWAS1361109_H GCST90239676 Total cholesterol levels 1,320,016 European ancestry individuals G 0.0139319 6E-23 22.222 rs148349043 0.0701836 total cholesterol measurement (EFO:0004574)
 PMID:34887591
GWAS1362083_H GCST90239655 Low density lipoprotein cholesterol levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-41 40.523 rs148349043 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:34887591
GWAS1381499_H GCST90446535 Cardiovascular disease 44,238 European ancestry cases, 414,900 European ancestry controls ? NR 5E-9 8.302 rs148349043 N/A cardiovascular disease (EFO:0000319)
 PMID:37947095
GWAS1761062_H GCST90446534 Coronary heart disease 38,687 European ancestry cases, 420,451 European ancestry controls ? NR 1E-9 9 rs148349043 N/A coronary artery disease (EFO:0001645)
 PMID:37947095
1 to 20 of 27 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90092967 GWAS Catalog

Note Type Note Reference