GWAS1259672_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1259672_H (factor VIII measurement, coronary artery disease QTL GWAS1259672 (human)) Homo sapiens

Symbol: GWAS1259672_H
Name: factor VIII measurement, coronary artery disease QTL GWAS1259672 (human)
RGD ID: 597163598
Trait: factor VIII measurement, coronary artery disease
LOD Score: Not Available
P Value: 2.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38625,691,923 - 25,691,924RGD_MAPPER_PIPELINEGRCh38
GRCh37625,692,151 - 25,692,152RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1259672_HHumancoronary artery disease  IAGPrs77737921405850206 GWAS_CATALOGPMID:35285134

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1259672_HHumanCoronary artery atherosclerosis  IAGPrs77737921405850206 GWAS_CATALOGPMID:35285134
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1259672_HHumancoronary artery disease  IAGPrs77737921405850206 GWAS_CATALOGPMID:35285134
GWAS1259672_HHumanfactor VIII measurement  IAGPrs77737921405850206 GWAS_CATALOGPMID:35285134

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1347901SCGNsecretagogin, EF-hand calcium binding protein62565221525701783Human
151672878LOC124901284uncharacterized LOC12490128462568187325698974Human


Peak: (rs77737921)
Human AssemblyChrPosition (strand)Source
GRCh38625,691,923 - 25,691,924RGD_MAPPER_PIPELINE


1 to 9 of 9 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1358839MULTSCL5_HMultiple sclerosis susceptibility QTL 5 (human)Multiple sclerosis susceptibility61958431145584311Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
597163598GWAS1259672_Hfactor VIII measurement, coronary artery disease QTL GWAS1259672 (human)2e-09factor VIII measurement, coronary artery disease62569192325691924Human
1298431RA11_HRheumatoid arthritis QTL 11 (human)0.0000024Joint/bone inflammationrheumatoid arthritis61991188340191709Human
1358857MULTSCL19_HMultiple sclerosis susceptibility QTL 19 (human)Multiple sclerosis susceptibility61958431145584311Human
1643399BMD5_HBone mineral density QTL 5 (human)2.320.0005Bone mineral density6691196032911960Human

1 to 9 of 9 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1259672_H GCST90129543 Coronary artery disease or factor VIII levels (pleiotropy) 172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 32,610 European, African American, East Asian, South Asian or Hispanic individuals with measurements ? NR 2E-9 8.699 rs77737921 N/A factor VIII measurement (EFO:0004630)
coronary artery disease (EFO:0001645)
 PMID:35285134
GWAS1756434_H GCST90129546 Coronary artery disease or fibrinogen levels (pleiotropy) 172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 120,246 European ancestry individuals with measurements ? NR 1E-9 9 rs77737921 N/A circulating fibrinogen levels (OBA:0000061)
coronary artery disease (EFO:0001645)
 PMID:35285134
Database
Acc Id
Source(s)
GWAS Catalog GCST90129543 GWAS Catalog

Note Type Note Reference