GWAS1231769_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1231769_H (diastolic blood pressure, systolic blood pressure QTL GWAS1231769 (human)) Homo sapiens

Symbol: GWAS1231769_H
Name: diastolic blood pressure, systolic blood pressure QTL GWAS1231769 (human)
RGD ID: 597135695
Trait: diastolic blood pressure, systolic blood pressure
Measurement Type: diastolic blood pressure   (CMO:0000005)    
systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 7.0E-7
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3862,005,235 - 2,005,236RGD_MAPPER_PIPELINEGRCh38
GRCh3762,005,469 - 2,005,470RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1231769_HHumandiastolic blood pressure  IAGPrs9378667405850206 GWAS_CATALOGPMID:34989438
GWAS1231769_HHumansystolic blood pressure  IAGPrs9378667405850206 GWAS_CATALOGPMID:34989438

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1231769_HHumandiastolic blood pressure  IAGPrs9378667405850206 GWAS_CATALOGPMID:34989438
GWAS1231769_HHumansystolic blood pressure  IAGPrs9378667405850206 GWAS_CATALOGPMID:34989438

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1322234GMDSGDP-mannose 4,6-dehydratase616238062245605Human


Peak: (rs9378667)
Human AssemblyChrPosition (strand)Source
GRCh3862,005,235 - 2,005,236RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597135695GWAS1231769_Hdiastolic blood pressure, systolic blood pressure QTL GWAS1231769 (human)0.0000007diastolic blood pressure, systolic blood pressuresystolic blood pressure (CMO:0000004)620052352005236Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
2292824PRSTS5_HProstate tumor susceptibility QTL 5 (human)Prostate tumor susceptibility6119232373Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
1643495BW291_HBody Weight QTL 291 (human)2.13Body weightBMI6119321359Human
597319572GWAS1415646_Hdiastolic blood pressure, systolic blood pressure QTL GWAS1415646 (human)5e-09diastolic blood pressure, systolic blood pressuresystolic blood pressure (CMO:0000004)620052352005236Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1231769_H GCST90239828 Blood pressure (pleiotropy model 1 DBP adjusted for estimated causal effects x SBP) 757,601 European ancestry individuals, 318,891 European ancestry, African American or Afro-Caribbean, Native American ancestry, Asian ancestry individuals ? NR 7E-7 6.155 rs9378667 0.06339184 diastolic blood pressure (EFO:0006336)
systolic blood pressure (EFO:0006335)
 PMID:34989438
GWAS1415646_H GCST90239829 Blood pressure (pleiotropy model 2 SBP adjusted for estimated causal effects x DBP) 757,601 European ancestry individuals, 318,891 European ancestry, African American or Afro-Caribbean, Native American ancestry, Asian ancestry individuals ? NR 5E-9 8.302 rs9378667 0.15000026 diastolic blood pressure (EFO:0006336)
systolic blood pressure (EFO:0006335)
 PMID:34989438
Database
Acc Id
Source(s)
GWAS Catalog GCST90239828 GWAS Catalog

Note Type Note Reference