GWAS1215733_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1215733_H (alkaline phosphatase measurement QTL GWAS1215733 (human)) Homo sapiens

Symbol: GWAS1215733_H
Name: alkaline phosphatase measurement QTL GWAS1215733 (human)
RGD ID: 597119659
Trait: alkaline phosphatase measurement
Measurement Type: blood alkaline phosphatase activity level   (CMO:0000576)    
LOD Score: Not Available
P Value: 1E-480
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38121,563,212 - 21,563,213RGD_MAPPER_PIPELINEGRCh38
GRCh37121,889,705 - 21,889,706RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1215733_HHumanblood alkaline phosphatase activity level  IAGPrs758734017405850206 GWAS_CATALOGPMID:34226706

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1215733_HHumanalkaline phosphatase measurement  IAGPrs758734017405850206 GWAS_CATALOGPMID:34226706

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1346147ALPLalkaline phosphatase, biomineralization associated12150898421578410Human


Peak: (rs758734017)
Human AssemblyChrPosition (strand)Source
GRCh38121,563,212 - 21,563,213RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597119282GWAS1215356_Hblood phosphate measurement QTL GWAS1215356 (human)3e-37blood phosphate amount (VT:0001565)blood phosphate level (CMO:0000504)12156321221563213Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597119659GWAS1215733_Halkaline phosphatase measurement QTL GWAS1215733 (human)1e-480alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)12156321221563213Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1215733_H GCST90025947 Serum alkaline phosphatase levels 437,896 European ancestry individuals ? NR 1E-480 480 rs758734017 2.1021 alkaline phosphatase measurement (EFO:0004533)
 PMID:34226706
GWAS1215356_H GCST90025948 Serum phosphate levels 400,159 European ancestry individuals ? NR 3E-37 36.523 rs758734017 0.675591 blood phosphate measurement (EFO:0010972)
 PMID:34226706
Database
Acc Id
Source(s)
GWAS Catalog GCST90025947 GWAS Catalog

Note Type Note Reference