GWAS1189332_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1189332_H (ulcerative colitis QTL GWAS1189332 (human)) Homo sapiens

Symbol: GWAS1189332_H
Name: ulcerative colitis QTL GWAS1189332 (human)
RGD ID: 597093258
Trait: ulcerative colitis
LOD Score: Not Available
P Value: 3.0E-76
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38119,845,367 - 19,845,368RGD_MAPPER_PIPELINEGRCh38
GRCh37120,171,860 - 20,171,861RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1189332_HHumanulcerative colitis  IAGPrs6426833405850206 GWAS_CATALOGPMID:26192919

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1189332_HHumanUlcerative colitis  IAGPrs6426833405850206 GWAS_CATALOGPMID:26192919
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1189332_HHumanulcerative colitis  IAGPrs6426833405850206 GWAS_CATALOGPMID:26192919

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs6426833)
Human AssemblyChrPosition (strand)Source
GRCh38119,845,367 - 19,845,368RGD_MAPPER_PIPELINE


1 to 10 of 22 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407388360GWAS1037336_Hankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis QTL GWAS1037336 (human)7e-62intestine integrity trait (VT:0010554)11984536719845368Human
406929025GWAS578001_Hulcerative colitis QTL GWAS578001 (human)4e-35ulcerative colitis11984536719845368Human
597287096GWAS1383170_Hulcerative colitis QTL GWAS1383170 (human)1e-74ulcerative colitis11984536719845368Human
407224807GWAS873783_Hulcerative colitis QTL GWAS873783 (human)2e-21ulcerative colitis11984536719845368Human
597289626GWAS1385700_Hinflammatory bowel disease QTL GWAS1385700 (human)8e-44inflammatory bowel disease11984536719845368Human
406977158GWAS626134_Hulcerative colitis QTL GWAS626134 (human)5e-13ulcerative colitis11984536719845368Human
597021404GWAS1117478_Hulcerative colitis QTL GWAS1117478 (human)3e-42ulcerative colitis11984536719845368Human
406889610GWAS538586_Hulcerative colitis QTL GWAS538586 (human)2e-11ulcerative colitis11984536719845368Human
597092188GWAS1188262_Hulcerative colitis QTL GWAS1188262 (human)1e-55ulcerative colitis11984536719845368Human

1 to 10 of 22 rows


1 to 16 of 16 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1189332_H GCST003045 Ulcerative colitis 6,968 European ancestry cases, 20,464 European ancestry controls A 0.54 3E-76 75.523 rs6426833 1.2616084 ulcerative colitis (EFO:0000729)
 PMID:26192919
GWAS538586_H GCST000527 Ulcerative colitis 2,361 European ancestry cases, 5,417 European ancestry controls ? NR 2E-11 10.699 rs6426833 N/A ulcerative colitis (EFO:0000729)
 PMID:19915572
GWAS1117015_H GCST004131 Inflammatory bowel disease 25,042 European and unknown ancestry cases, 34,915 European and unknown ancestry controls ? NR 1E-19 19 rs6426833 N/A inflammatory bowel disease (EFO:0003767)
 PMID:28067908
GWAS1117478_H GCST004133 Ulcerative colitis 12,366 European and unknown ancestry cases, 33,609 European and unknown ancestry controls ? NR 3E-42 41.523 rs6426833 N/A ulcerative colitis (EFO:0000729)
 PMID:28067908
GWAS578001_H GCST000964 Ulcerative colitis 6,687 European ancestry cases, 19,718 European ancestry controls A 0.54 4E-35 34.398 rs6426833 1.3 ulcerative colitis (EFO:0000729)
 PMID:21297633
GWAS623080_H GCST001728 Ulcerative colitis Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls A 0.542 2E-68 67.699 rs6426833 1.265 ulcerative colitis (EFO:0000729)
 PMID:23128233
GWAS626134_H GCST000311 Ulcerative colitis 1,022 European ancestry cases, 2,503 European ancestry controls G 0.54 5E-13 12.302 rs6426833 1.37 ulcerative colitis (EFO:0000729)
 PMID:19122664
GWAS1188262_H GCST003045 Ulcerative colitis 6,968 European ancestry cases, 20,464 European ancestry controls ? NR 1E-55 55 rs6426833 N/A ulcerative colitis (EFO:0000729)
 PMID:26192919
GWAS1188708_H GCST003043 Inflammatory bowel disease 12,882 European ancestry cases, 21,770 European ancestry controls A 0.54 3E-36 35.523 rs6426833 1.1322339 inflammatory bowel disease (EFO:0003767)
 PMID:26192919
GWAS1218255_H GCST90016611 Crohn's disease vs ulcerative colitis (ordinary least squares (OLS)) 5,956 Crohn's disease cases, 6,968 ulcerative colitis cases ? NR 3E-18 17.523 rs6426833 0.053 ulcerative colitis (EFO:0000729)
Crohn's disease (EFO:0000384)
 PMID:33686288
None Available GCST90480319 Ulcerative colitis 857 African American or Afro-Caribbean cases, 119,909 African American or Afro-Caribbean controls, 5,229 European ancestry cases, 442,102 European ancestry controls, 529 Hispanic or Latin American cases, 58,892 Hispanic or Latin American controls G 0.4789 5E-13 12.302 rs6426833 0.1318 ulcerative colitis (EFO:0000729)
 PMID:39024449
GWAS873783_H GCST000624 Ulcerative colitis 2,693 European ancestry cases, 6,791 European ancestry controls A NR 2E-21 20.699 rs6426833 1.3 ulcerative colitis (EFO:0000729)
 PMID:20228799
GWAS1383170_H GCST90446794 Ulcerative colitis 6,862 East Asian ancestry cases, 15,456 East Asian ancestry controls, 16,390 European ancestry cases, 336,800 European ancestry controls ? NR 1E-74 74 rs6426833 0.2167 ulcerative colitis (EFO:0000729)
 PMID:37156999
GWAS1385700_H GCST90292538 Inflammatory bowel disease 14,393 East Asian ancestry cases, 15,456 East Asian ancestry controls, 30,713 European ancestry cases, 338,106 European ancestry controls ? NR 8E-44 43.097 rs6426833 0.1311 inflammatory bowel disease (EFO:0003767)
 PMID:37156999
GWAS1387346_H GCST90454275 Ulcerative colitis 3,788 European ancestry cases, 373,083 European ancestry controls G NR 7E-12 11.155 rs6426833 0.85 ulcerative colitis (EFO:0000729)
 PMID:37002690
GWAS1037336_H GCST005537 Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) 8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls ? NR 7E-62 61.155 rs6426833 N/A ankylosing spondylitis (EFO:0003898)
psoriasis (EFO:0000676)
ulcerative colitis (EFO:0000729)
Crohn's disease (EFO:0000384)
More... 		PMID:26974007
1 to 16 of 16 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST003045 GWAS Catalog

Note Type Note Reference