GWAS1188234_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1188234_H (Alzheimer disease, age at onset QTL GWAS1188234 (human)) Homo sapiens

Symbol: GWAS1188234_H
Name: Alzheimer disease, age at onset QTL GWAS1188234 (human)
RGD ID: 597092160
Trait: Alzheimer disease, age at onset
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38618,173,684 - 18,173,685RGD_MAPPER_PIPELINEGRCh38
GRCh37618,173,915 - 18,173,916RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1188234_HHumanAlzheimer's disease  IAGPrs188911996405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:26830138

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1188234_HHumanAlzheimer disease  IAGPrs188911996405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:26830138
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1188234_HHumanage at onset  IAGPrs188911996405850206 GWAS_CATALOGPMID:26830138

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1321760KDM1Blysine demethylase 1B61815542218223854Human


Peak: (rs188911996)
Human AssemblyChrPosition (strand)Source
GRCh38618,173,684 - 18,173,685RGD_MAPPER_PIPELINE


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597092160GWAS1188234_HAlzheimer disease, age at onset QTL GWAS1188234 (human)2e-08Alzheimer disease, age at onset61817368418173685Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2292824PRSTS5_HProstate tumor susceptibility QTL 5 (human)Prostate tumor susceptibility6119232373Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human

1 to 10 of 12 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1188234_H GCST003427 Alzheimer disease and age of onset 2,478 European ancestry cases, 979 ancestry controls both from the same 1,070 families A NR 2E-8 7.699 rs188911996 5.578 age at onset (EFO:0004847)
 PMID:26830138
Database
Acc Id
Source(s)
GWAS Catalog GCST003427 GWAS Catalog

Note Type Note Reference