GWAS1187938_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1187938_H (BMI-adjusted waist circumference QTL GWAS1187938 (human)) Homo sapiens

Symbol: GWAS1187938_H
Name: BMI-adjusted waist circumference QTL GWAS1187938 (human)
RGD ID: 597091864
Trait: body size trait   (VT:0100005)    
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38975,927,370 - 75,927,371RGD_MAPPER_PIPELINEGRCh38
GRCh37978,542,286 - 78,542,287RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1187938_HHumanbody size trait  IAGPrs11144688405850206 GWAS_CATALOGPMID:25673412

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1187938_HHumanBMI-adjusted waist circumference  IAGPrs11144688405850206 GWAS_CATALOGPMID:25673412

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
732125PCSK5proprotein convertase subtilisin/kexin type 597588980976362975Human


Peak: (rs11144688)
Human AssemblyChrPosition (strand)Source
GRCh38975,927,370 - 75,927,371RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597070382GWAS1166456_HBMI-adjusted waist circumference QTL GWAS1166456 (human)0.000001body size trait (VT:0100005)97592737075927371Human
597062284GWAS1158358_Hsmoking behavior, BMI-adjusted waist circumference QTL GWAS1158358 (human)0.000004body size trait (VT:0100005)97592737075927371Human
597069884GWAS1165958_Hsmoking behavior, BMI-adjusted waist circumference QTL GWAS1165958 (human)0.000005body size trait (VT:0100005)97592737075927371Human
597091864GWAS1187938_HBMI-adjusted waist circumference QTL GWAS1187938 (human)2e-08body size trait (VT:0100005)97592737075927371Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1187938_H GCST004063 Waist circumference adjusted for body mass index up to 56,910 European ancestry men, up to 86,570 European ancestry women A 0.1258 2E-8 7.699 rs11144688 0.0336 BMI-adjusted waist circumference (EFO:0007789)
 PMID:25673412
GWAS1700587_H GCST001956 Height 8,097 European ancestry tall individuals, 8,099 European ancestry short individuals G 0.89 4E-16 15.398 rs11144688 1.48 body height (OBA:VT0001253)
 PMID:23563607
GWAS1701684_H GCST000817 Height 133,653 European ancestry individuals A 0.11 1E-11 11 rs11144688 0.049 body height (OBA:VT0001253)
 PMID:20881960
GWAS1707346_H GCST002647 Height 253,288 European ancestry individuals A 0.108 6E-24 23.222 rs11144688 0.063 body height (OBA:VT0001253)
 PMID:25282103
GWAS1158358_H GCST004500 Waist circumference adjusted for BMI (adjusted for smoking behaviour) 97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men A 0.1159 0.000004 5.398 rs11144688 0.0308 smoking behavior (EFO:0004318)
BMI-adjusted waist circumference (EFO:0007789)
 PMID:28443625
GWAS1165958_H GCST004501 Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) 97,400 European ancestry women, 63,892 European ancestry men, 5,829 European ancestry individuals, 10,500 African American/Afro-Caribbean ancestry women, 2,706 African American/Afro-Caribbean ancestry men, 1,030 Indian Asian ancestry women, 7,648 Indian Asian ancestry men, 1,793 Filipino ancestry women, 2,944 Hispanic/Latino ancestry women, 1,764 Hispanic/Latino ancestry men A 0.1159 0.000005 5.302 rs11144688 N/A smoking behavior (EFO:0004318)
BMI-adjusted waist circumference (EFO:0007789)
 PMID:28443625
GWAS1166456_H GCST004504 Waist circumference adjusted for BMI in non-smokers 77,113 European ancestry women, 47,319 European ancestry men, 4,856 European ancestry individuals, 8,799 African American/Afro-Caribbean ancestry women, 1,803 African American/Afro-Caribbean ancestry men, 1,020 Indian Asian ancestry women, 6,691 Indian Asian ancestry men, 1,526 Filipino ancestry women, 2,469 Hispanic/Latino ancestry women, 1,318 Hispanic/Latino ancestry men A 0.1159 0.000001 6 rs11144688 0.0362 BMI-adjusted waist circumference (EFO:0007789)
 PMID:28443625
Database
Acc Id
Source(s)
GWAS Catalog GCST004063 GWAS Catalog

Note Type Note Reference