GWAS1186952_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1186952_H (type 2 diabetes mellitus QTL GWAS1186952 (human)) Homo sapiens

Symbol: GWAS1186952_H
Name: type 2 diabetes mellitus QTL GWAS1186952 (human)
RGD ID: 597090878
Trait: type 2 diabetes mellitus
LOD Score: Not Available
P Value: 2.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382046,966,072 - 46,966,073RGD_MAPPER_PIPELINEGRCh38
GRCh372045,594,711 - 45,594,712RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1186952_HHumantype 2 diabetes mellitus  IAGPrs6066138405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:32541925


#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1350703EYA2EYA transcriptional coactivator and phosphatase 2204689484347188844Human


Peak: (rs6066138)
Human AssemblyChrPosition (strand)Source
GRCh382046,966,072 - 46,966,073RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597207016GWAS1303090_Htype 2 diabetes mellitus QTL GWAS1303090 (human)2e-09type 2 diabetes mellitus204696607246966073Human
1300007BP29_HBlood pressure QTL 29 (human)Blood pressurehypertension susceptibility203653600562536005Human
597090878GWAS1186952_Htype 2 diabetes mellitus QTL GWAS1186952 (human)2e-18type 2 diabetes mellitus204696607246966073Human
597087182GWAS1183256_Htype 2 diabetes mellitus QTL GWAS1183256 (human)6e-19type 2 diabetes mellitus204696607246966073Human
597269010GWAS1365084_Htriglyceride measurement QTL GWAS1365084 (human)3e-19triglyceride measurementblood triglyceride level (CMO:0000118)204696607246966073Human
597272148GWAS1368222_Htriglyceride measurement QTL GWAS1368222 (human)3e-28triglyceride measurementblood triglyceride level (CMO:0000118)204696607246966073Human
597314615GWAS1410689_Htriglyceride measurement QTL GWAS1410689 (human)2e-14triglyceride measurementblood triglyceride level (CMO:0000118)204696607246966073Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1186952_H GCST010555 Type 2 diabetes 148,726 European ancestry cases, 965,732 European ancestry controls G 0.7252 2E-18 17.699 rs6066138 0.0451 PMID:32541925
GWAS1183256_H GCST010557 Type 2 diabetes 148,726 European ancestry cases, 24,646 African American cases, 8,616 Hispanic cases, 46,511 Asian ancestry cases, 965,732 European ancestry controls, 31,446 African American controls, 11,829 Hispanic controls, 169,776 Asian ancestry controls G 0.7376 6E-19 18.222 rs6066138 0.042 PMID:32541925
GWAS1303090_H GCST006867 Type 2 diabetes 61,714 European ancestry cases, 1,178 Pakistani ancestry cases, 593,952 European ancestry controls, 2,472 Pakistani ancestry controls A 0.278361954233567 2E-9 8.699 rs6066138 0.049 PMID:30054458
GWAS1365084_H GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals A 0.273646 3E-19 18.523 rs6066138 0.0171088 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS1368222_H GCST90239661 Triglyceride levels 40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals ? NR 3E-28 27.523 rs6066138 N/A triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS1410689_H GCST90018975 Triglycerides 343,992 European ancestry individuals, 111,667 East Asian ancestry individuals A NR 2E-14 13.699 rs6066138 0.0198 triglyceride measurement (EFO:0004530)
 PMID:34594039
Database
Acc Id
Source(s)
GWAS Catalog GCST010555 GWAS Catalog

Note Type Note Reference