GWAS1170757_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1170757_H (Dupuytren Contracture QTL GWAS1170757 (human)) Homo sapiens

Symbol: GWAS1170757_H
Name: Dupuytren Contracture QTL GWAS1170757 (human)
RGD ID: 597074683
Trait: Dupuytren Contracture
LOD Score: Not Available
P Value: 3.0E-15
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38122,371,954 - 22,371,955RGD_MAPPER_PIPELINEGRCh38
GRCh37122,698,447 - 22,698,448RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1170757_HHumanDupuytren Contracture  IAGPrs7524102405850206 GWAS_CATALOGPMID:28886342

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1170757_HHumanDupuytren contracture  IAGPrs7524102405850206 GWAS_CATALOGPMID:28886342
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1170757_HHumanDupuytren Contracture  IAGPrs7524102405850206 GWAS_CATALOGPMID:28886342

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records



Peak: (rs7524102)
Human AssemblyChrPosition (strand)Source
GRCh38122,371,954 - 22,371,955RGD_MAPPER_PIPELINE


1 to 10 of 17 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407127620GWAS776596_Hulcerative colitis QTL GWAS776596 (human)2e-13ulcerative colitis12237195422371955Human
597307002GWAS1403076_Hfemoral neck bone mineral density QTL GWAS1403076 (human)4e-16bone mineralization trait (VT:0002896)bone mineral density (CMO:0001226)12237195422371955Human
597305017GWAS1401091_Hspine bone mineral density QTL GWAS1401091 (human)6e-18spine bone mineral densitybone mineral density (CMO:0001226)12237195422371955Human
597296371GWAS1392445_Hhematocrit QTL GWAS1392445 (human)2e-11hematocrithematocrit (CMO:0000037)12237195422371955Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597019705GWAS1115779_Hspine bone mineral density QTL GWAS1115779 (human)5e-18spine bone mineral densitybone mineral density (CMO:0001226)12237195422371955Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
597074683GWAS1170757_HDupuytren Contracture QTL GWAS1170757 (human)3e-15Dupuytren Contracture12237195422371955Human
597307253GWAS1403327_Hspine bone mineral density QTL GWAS1403327 (human)6e-19spine bone mineral densitybone mineral density (CMO:0001226)12237195422371955Human

1 to 10 of 17 rows


1 to 20 of 20 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1170757_H GCST004858 Dupuytren's disease 3,871 European ancestry cases, 4,686 European ancestry controls G 0.214 3E-15 14.523 rs7524102 1.351 Dupuytren Contracture (EFO:0004229)
 PMID:28886342
GWAS1699212_H GCST001050 Bone mineral density 900 European ancestry female individuals with low hip bone mineral density, 1,055 European ancestry female individuals with high hip bone mineral density G NR 9E-7 6.046 rs7524102 0.44 bone density (OBA:1000110)
 PMID:21533022
GWAS1699216_H GCST001050 Bone mineral density 900 European ancestry female individuals with low hip bone mineral density, 1,055 European ancestry female individuals with high hip bone mineral density G NR 0.000001 6 rs7524102 0.14 bone density (OBA:1000110)
 PMID:21533022
GWAS1115754_H GCST005795 Femoral neck bone mineral density up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals A 0.830289 1E-20 20 rs7524102 0.0828 femoral neck bone mineral density (EFO:0007785)
 PMID:29499414
GWAS1115779_H GCST005796 Lumbar spine bone mineral density up to 4,692 European ancestry individuals, up to 1,539 Han Chinese ancestry individuals, up to 849 African American individuals, up to 446 Hispanic individuals, 2,882 European ancestry whole-genome sequenced individuals, 3,549 European ancestry whole-exome sequenced individuals, 26,534 European ancestry non-array genotype imputed individuals A 0.830289 5E-18 17.302 rs7524102 0.087 spine bone mineral density (EFO:0007701)
 PMID:29499414
GWAS1699957_H GCST000494 Bone mineral density (spine) 19,195 European ancestry individuals G 0.17 3E-10 9.523 rs7524102 0.09 bone density (OBA:1000110)
 PMID:19801982
GWAS1700280_H GCST000181 Bone mineral density (hip) 5,861 European ancestry individuals A 0.82 5E-16 15.302 rs7524102 0.15 bone density (OBA:1000110)
 PMID:18445777
GWAS1700284_H GCST000180 Bone mineral density (spine) 5,861 European ancestry individuals A 0.82 9E-9 8.046 rs7524102 0.11 bone density (OBA:1000110)
 PMID:18445777
GWAS1701143_H GCST000297 Bone mineral density (hip) 6,865 European ancestry individuals A 0.82 1E-16 16 rs7524102 0.15 bone density (OBA:1000110)
 PMID:19079262
GWAS776596_H GCST000964 Ulcerative colitis 6,687 European ancestry cases, 19,718 European ancestry controls A 0.83 2E-13 12.699 rs7524102 1.1 ulcerative colitis (EFO:0000729)
 PMID:21297633
GWAS776712_H GCST000527 Ulcerative colitis 2,361 European ancestry cases, 5,417 European ancestry controls A 0.83 3E-7 6.523 rs7524102 1.1 ulcerative colitis (EFO:0000729)
 PMID:19915572
GWAS777571_H GCST001144 Dupuytren's disease 856 European ancestry cases, 2,836 European ancestry controls G 0.21 3E-9 8.523 rs7524102 1.28 Dupuytren Contracture (EFO:0004229)
 PMID:21732829
GWAS1380490_H GCST90018957 Hemoglobin 350,474 European ancestry individuals, 152,447 East Asian ancestry individuals G NR 1E-12 12 rs7524102 0.0146 hemoglobin measurement (EFO:0004509)
 PMID:34594039
GWAS1392445_H GCST90018960 Hematocrit 350,475 European ancestry individuals, 153,015 East Asian ancestry individuals G NR 2E-11 10.699 rs7524102 0.0141 hematocrit (EFO:0004348)
 PMID:34594039
GWAS1401087_H GCST90101815 Bone mineral density (femoral neck) 2,948 African American individuals, 39,107 European ancestry individuals, 2,451 Hispanic individuals ? NR 3E-22 21.523 rs7524102 N/A femoral neck bone mineral density (EFO:0007785)
 PMID:34673960
GWAS1401091_H GCST90101816 Bone mineral density (spine) 2,948 African American individuals, 39,107 European ancestry individuals, 2,451 Hispanic individuals ? NR 6E-18 17.222 rs7524102 N/A spine bone mineral density (EFO:0007701)
 PMID:34673960
GWAS1403076_H GCST90101817 Bone mineral density (femoral neck) 1,825 African American females, 26,724 European ancestry females, 1,683 Hispanic females ? NR 4E-16 15.398 rs7524102 N/A femoral neck bone mineral density (EFO:0007785)
 PMID:34673960
GWAS1403327_H GCST90101818 Bone mineral density (spine) 1,825 African American females, 26,724 European ancestry females, 1,683 Hispanic females ? NR 6E-19 18.222 rs7524102 N/A spine bone mineral density (EFO:0007701)
 PMID:34673960
GWAS1786537_H GCST90245848 Height 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals G 0.1818 3E-26 25.523 rs7524102 0.0084 body height (OBA:VT0001253)
 PMID:36224396
GWAS1792071_H GCST90321118 Bone mineral density mean 141,261 European ancestry individuals ? NR 1E-10 10 rs7524102 N/A bone density (OBA:1000110)
 PMID:37500982
1 to 20 of 20 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST004858 GWAS Catalog

Note Type Note Reference