GWAS1160889_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1160889_H (celiac disease QTL GWAS1160889 (human)) Homo sapiens

Symbol: GWAS1160889_H
Name: celiac disease QTL GWAS1160889 (human)
RGD ID: 597064815
Trait: celiac disease
LOD Score: Not Available
P Value: 2.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh386408,079 - 408,080RGD_MAPPER_PIPELINEGRCh38
GRCh376408,079 - 408,080RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1160889_HHumanceliac disease  IAGPrs1050976405850206 GWAS_CATALOGPMID:22057235

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1160889_HHumanCeliac disease  IAGPrs1050976405850206 GWAS_CATALOGPMID:22057235
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1160889_HHumanceliac disease  IAGPrs1050976405850206 GWAS_CATALOGPMID:22057235

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1317594IRF4interferon regulatory factor 46391752411443Human


Peak: (rs1050976)
Human AssemblyChrPosition (strand)Source
GRCh386408,079 - 408,080RGD_MAPPER_PIPELINE


1 to 10 of 13 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
597050778GWAS1146852_Hhypothyroidism QTL GWAS1146852 (human)5e-13hypothyroidism6408079408080Human
596962235GWAS1081754_Hmultiple myeloma QTL GWAS1081754 (human)2e-08multiple myeloma6408079408080Human
597081890GWAS1177964_Hautoimmune thyroid disease QTL GWAS1177964 (human)3e-14autoimmune thyroid disease6408079408080Human
597257455GWAS1353529_Hmultiple myeloma QTL GWAS1353529 (human)2e-08multiple myeloma6408079408080Human
597278895GWAS1374969_Hhypothyroidism QTL GWAS1374969 (human)7e-11hypothyroidism6408079408080Human
2289435BMD4_HBone mineral density QTL 4 (human)3.150.0001Bone mineral density6120803913Human
597064815GWAS1160889_Hceliac disease QTL GWAS1160889 (human)2e-09celiac disease6408079408080Human

1 to 10 of 13 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1160889_H GCST005523 Celiac disease 11,812 European ancestry cases, 229 Indian ancestry cases, 11,837 European ancestry controls, 391 Indian ancestry controls ? 0.512 2E-9 8.699 rs1050976 1.1235955 celiac disease (EFO:0001060)
 PMID:22057235
GWAS1146852_H GCST007073 Hypothyroidism approximately 459,000 European ancestry individuals ? NR 5E-13 12.302 rs1050976 N/A hypothyroidism (EFO:0004705)
 PMID:30595370
GWAS1177964_H GCST010571 Autoimmune thyroid disease 30,234 European ancestry cases, 724,172 European ancestry controls T 0.516 3E-14 13.523 rs1050976 1.07 autoimmune thyroid disease (EFO:0006812)
 PMID:32581359
GWAS1309135_H GCST006432 Multiple myeloma 8,197 European ancestry cases, 241,468 European ancestry controls T 0.51 6E-8 7.222 rs1050976 1.1 multiple myeloma (EFO:0001378)
 PMID:30213928
GWAS1353529_H GCST90451657 Multiple myeloma 10,906 European ancestry cases, 366,221 European ancestry controls T 0.475 2E-8 7.699 rs1050976 1.1 multiple myeloma (EFO:0001378)
 PMID:39103364
GWAS1374969_H GCST90204167 Hypothyroidism 51,194 European ancestry cases, 443,383 European ancestry controls T NR 7E-11 10.155 rs1050976 0.0518755 hypothyroidism (EFO:0004705)
 PMID:36093044
Database
Acc Id
Source(s)
GWAS Catalog GCST005523 GWAS Catalog

Note Type Note Reference