GWAS1157705_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1157705_H (FEV/FVC ratio QTL GWAS1157705 (human)) Homo sapiens

Symbol: GWAS1157705_H
Name: FEV/FVC ratio QTL GWAS1157705 (human)
RGD ID: 597061631
Trait: FEV/FVC ratio
Measurement Type: forced expiratory volume to forced vital capacity ratio   (CMO:0000241)    
LOD Score: Not Available
P Value: 1.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38311,600,640 - 11,600,641RGD_MAPPER_PIPELINEGRCh38
GRCh37311,642,114 - 11,642,115RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1157705_HHumanforced expiratory volume to forced vital capacity ratio  IAGPrs1561073405850206 GWAS_CATALOGPMID:30595370

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1157705_HHumanFEV/FVC ratio  IAGPrs1561073405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1323223VGLL4vestigial like family member 431155606711721815Human
150520006LOC122889034Sharpr-MPRA regulatory region 825431160059511600889Human


Peak: (rs1561073)
Human AssemblyChrPosition (strand)Source
GRCh38311,600,640 - 11,600,641RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597167357GWAS1263431_Hbody mass index QTL GWAS1263431 (human)2e-11body mass indexbody mass index (BMI) (CMO:0000105)31160064011600641Human
597061631GWAS1157705_HFEV/FVC ratio QTL GWAS1157705 (human)1e-20FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)31160064011600641Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
597147035GWAS1243109_Hchronic obstructive pulmonary disease QTL GWAS1243109 (human)5e-20lung integrity trait (VT:0010906)31160064011600641Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1157705_H GCST007080 Lung function (FEV1/FVC) approximately 370,000 European ancestry individuals ? NR 1E-20 20 rs1561073 N/A FEV/FVC ratio (EFO:0004713)
 PMID:30595370
GWAS1243109_H GCST90244098 Chronic obstructive pulmonary disease liability (machine learning-based score) 325,027 European ancestry individuals T NR 5E-20 19.302 rs1561073 0.0214971 chronic obstructive pulmonary disease (EFO:0000341)
 PMID:37069358
GWAS1263431_H GCST90018947 Body mass index 359,983 European ancestry individuals, 163,835 East Asian ancestry individuals A NR 2E-11 10.699 rs1561073 0.0139 body mass index (EFO:0004340)
 PMID:34594039
Database
Acc Id
Source(s)
GWAS Catalog GCST007080 GWAS Catalog

Note Type Note Reference