GWAS1154233_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1154233_H (respiratory system disease QTL GWAS1154233 (human)) Homo sapiens

Symbol: GWAS1154233_H
Name: respiratory system disease QTL GWAS1154233 (human)
RGD ID: 597058159
Trait: respiratory system disease
LOD Score: Not Available
P Value: 3.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38110,573,188 - 10,573,189RGD_MAPPER_PIPELINEGRCh38
GRCh37110,633,245 - 10,633,246RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1154233_HHumanasthma  IAGPrs6687430405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:36777996
GWAS1154233_HHumanrespiratory system disease  IAGPrs6687430405850206 GWAS_CATALOGPMID:30595370

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1154233_HHumanAbnormality of the respiratory system  IAGPrs6687430405850206 GWAS_CATALOGPMID:30595370
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1154233_HHumanrespiratory system disease  IAGPrs6687430405850206 GWAS_CATALOGPMID:30595370

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
68470PEX14peroxisomal biogenesis factor 1411047495010630758Human


Peak: (rs6687430)
Human AssemblyChrPosition (strand)Source
GRCh38110,573,188 - 10,573,189RGD_MAPPER_PIPELINE


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407092224GWAS741200_Hhair color QTL GWAS741200 (human)1e-08hair color11057318810573189Human
597076320GWAS1172394_Hgrip strength measurement QTL GWAS1172394 (human)6e-11grip strength measurement11057318810573189Human
407305678GWAS954654_Hasthma QTL GWAS954654 (human)7e-11asthma11057318810573189Human
597058159GWAS1154233_Hrespiratory system disease QTL GWAS1154233 (human)3e-09asthma11057318810573189Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
407303850GWAS952826_Hasthma QTL GWAS952826 (human)8e-13asthma11057318810573189Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human

1 to 10 of 12 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1154233_H GCST007076 Respiratory diseases approximately 459,000 European ancestry individuals ? NR 3E-9 8.523 rs6687430 N/A respiratory system disease (EFO:0000684)
 PMID:30595370
GWAS1172394_H GCST005235 Hand grip strength 142,035 European ancestry individuals G 0.459 6E-11 10.222 rs6687430 0.1423 grip strength measurement (EFO:0006941)
 PMID:29313844
GWAS741200_H GCST006988 Blond vs. brown/black hair color 39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals G 0.4588 1E-8 8 rs6687430 1.045 hair color (EFO:0003924)
 PMID:30531825
GWAS1261120_H GCST90018795 Asthma 38,369 European ancestry cases, 411,131 European ancestry controls, 13,015 East Asian ancestry cases, 162,933 East Asian ancestry controls A NR 2E-9 8.699 rs6687430 0.0431 PMID:34594039
GWAS1343073_H GCST90014325 Asthma 56,167 White-British ancestry cases, 352,255 White-British ancestry controls A 0.541066592886769 3E-8 7.523 rs6687430 0.036332093 PMID:34103634
GWAS952826_H GCST010043 Asthma 84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls A 0.54 8E-13 12.097 rs6687430 N/A PMID:32296059
GWAS954654_H GCST010042 Asthma 64,538 European ancestry cases, 239,321 European ancestry controls A 0.541675 7E-11 10.155 rs6687430 1.0400028 PMID:32296059
None Available GCST90399687 Asthma 139 Middle Eastern ancestry cases, 1,434 Middle Eastern ancestry controls, 4,069 Admixed American ancestry cases, 14,104 Admixed American ancestry controls, 4,015 South Asian ancestry cases, 27,091 South Asian ancestry controls, 5,051 African ancestry cases, 27,607 African ancestry controls, 18,549 East Asian ancestry cases, 322,655 East Asian ancestry controls, 121,940 European ancestry cases, 1,254,131 European ancestry controls A 0.5921 3E-9 8.523 rs6687430 0.026156 PMID:36777996
Database
Acc Id
Source(s)
GWAS Catalog GCST007076 GWAS Catalog
  GCST90399687 GWAS Catalog

Note Type Note Reference