GWAS1152095_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1152095_H (basophil count QTL GWAS1152095 (human)) Homo sapiens

Symbol: GWAS1152095_H
Name: basophil count QTL GWAS1152095 (human)
RGD ID: 597056021
Trait: basophil quantity   (VT:0002607)    
Measurement Type: blood basophil count   (CMO:0000034)    
blood granulocyte count   (CMO:0000111)    
LOD Score: Not Available
P Value: 2.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38690,296,508 - 90,296,509RGD_MAPPER_PIPELINEGRCh38
GRCh37691,006,227 - 91,006,228RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1152095_HHumanblood basophil count  IAGPrs1504215405850206 GWAS_CATALOGPMID:32888493
GWAS1152095_HHumanblood granulocyte count  IAGPrs1504215405850206 GWAS_CATALOGPMID:32888493

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1152095_HHumanbasophil quantity  IAGPrs1504215405850206 GWAS_CATALOGPMID:32888493

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1152095_HHumanbasophil count  IAGPrs1504215405850206 GWAS_CATALOGPMID:32888493

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1319503BACH2BTB domain and CNC homolog 268992652890296843Human


Peak: (rs1504215)
Human AssemblyChrPosition (strand)Source
GRCh38690,296,508 - 90,296,509RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597110327GWAS1206401_HInhalant adrenergic use measurement QTL GWAS1206401 (human)1e-18Inhalant adrenergic use measurement69029650890296509Human
597056021GWAS1152095_Hbasophil count QTL GWAS1152095 (human)2e-10basophil quantity (VT:0002607)blood basophil count (CMO:0000034)69029650890296509Human
407249600GWAS898576_Hasthma QTL GWAS898576 (human)2e-46asthma69029650890296509Human
597109600GWAS1205674_HGlucocorticoid use measurement QTL GWAS1205674 (human)1e-13Glucocorticoid use measurement69029650890296509Human
597326146GWAS1422220_HFEV/FVC ratio QTL GWAS1422220 (human)2e-11FEV/FVC ratioforced expiratory volume to forced vital capacity ratio (CMO:0000241)69029650890296509Human
1298426BFD3_HBody fluid distribution QTL 3 (human)2.790.01Body fluid distributionimpedance ratio684873647110873647Human
597048956GWAS1145030_Hallergic rhinitis QTL GWAS1145030 (human)2e-18allergic rhinitis69029650890296509Human



1 to 9 of 9 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1152095_H GCST90002296 Basophil count 577,663 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals A 0.338542 2E-10 9.699 rs1504215 N/A basophil count (EFO:0005090)
 PMID:32888493
GWAS1145030_H GCST006409 Allergic rhinitis 59,762 European and unknown ancestry cases, 152,358 European and unknown ancestry controls G 0.6575 2E-18 17.699 rs1504215 1.0526316 allergic rhinitis (EFO:0005854)
 PMID:30013184
GWAS1205674_H GCST007942 Medication use (glucocorticoids) 17,352 European ancestry cases, 188,348 European ancestry controls A 0.350757 1E-13 13 rs1504215 0.08696847 Glucocorticoid use measurement (EFO:0009942)
 PMID:31015401
GWAS1206401_H GCST007941 Medication use (adrenergics, inhalants) 28,880 European ancestry cases, 147,565 European ancestry controls A 0.349167 1E-18 18 rs1504215 0.083247945 Inhalant adrenergic use measurement (EFO:0009941)
 PMID:31015401
GWAS1734025_H GCST90002363 Red blood cell count 545,203 European ancestry individuals A 0.346442 2E-24 23.699 rs1504215 0.019813 red blood cell density (OBA:2045260)
 PMID:32888493
GWAS898576_H GCST010043 Asthma 84,492 European ancestry cases, 2,149 African American cases, 606 Hispanic cases, 1,239 Japanese ancestry cases, 437,036 European ancestry controls, 6,055 African American controls, 792 Hispanic controls, 3,976 Japanese ancestry controls G 0.66 2E-46 45.699 rs1504215 N/A PMID:32296059
None Available GCST90018999 Medication use (adrenergics, inhalants) 28,880 European ancestry cases, 147,565 European ancestry controls, 5,880 East Asian ancestry cases, 172,846 East Asian ancestry controls A NR 1E-18 18 rs1504215 0.0832 Inhalant adrenergic use measurement (EFO:0009941)
 PMID:34594039
None Available GCST90019000 Medication use (glucocorticoids) 17,352 European ancestry cases, 188,348 European ancestry controls, 13,102 East Asian ancestry cases, 165,624 East Asian ancestry controls A NR 1E-13 13 rs1504215 0.087 Glucocorticoid use measurement (EFO:0009942)
 PMID:34594039
GWAS1422220_H GCST90244094 Lung function (FEV1/FVC) 475,645 European ancestry individuals, 8,590 African ancestry individuals, 85,279 East Asian ancestry individuals, 4,270 South Asian ancestry individuals, 14,668 Hispanic or Latin American individuals A 0.289 2E-11 10.699 rs1504215 6.74 FEV/FVC ratio (EFO:0004713)
 PMID:36914875
1 to 9 of 9 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90002296 GWAS Catalog

Note Type Note Reference