GWAS1149641_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1149641_H (eosinophil count QTL GWAS1149641 (human)) Homo sapiens

Symbol: GWAS1149641_H
Name: eosinophil count QTL GWAS1149641 (human)
RGD ID: 597053567
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count   (CMO:0000033)    
LOD Score: Not Available
P Value: 2.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382050,545,649 - 50,545,650RGD_MAPPER_PIPELINEGRCh38
GRCh372049,162,186 - 49,162,187RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1149641_HHumanblood eosinophil count  IAGPrs6126042405850206 GWAS_CATALOGPMID:32888494

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1149641_HHumaneosinophil quantity  IAGPrs6126042405850206 GWAS_CATALOGPMID:32888494

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1149641_HHumaneosinophil count  IAGPrs6126042405850206 GWAS_CATALOGPMID:32888494

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1343639PTPN1protein tyrosine phosphatase non-receptor type 1205051038350585241Human


Peak: (rs6126042)
Human AssemblyChrPosition (strand)Source
GRCh382050,545,649 - 50,545,650RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2292864PRSTS43_HProstate tumor susceptibility QTL 43 (human)0.620.05Prostate tumor susceptibility204730303964444167Human
1300007BP29_HBlood pressure QTL 29 (human)Blood pressurehypertension susceptibility203653600562536005Human
597053567GWAS1149641_Heosinophil count QTL GWAS1149641 (human)2e-18eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)205054564950545650Human
406939130GWAS588106_Heosinophil percentage of leukocytes QTL GWAS588106 (human)1e-20eosinophil quantity (VT:0002602)blood eosinophil count to total leukocyte count ratio (CMO:0000369)205054564950545650Human
407110360GWAS759336_Heosinophil count QTL GWAS759336 (human)4e-19eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)205054564950545650Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1149641_H GCST90002381 Eosinophil counts 408,112 British individuals T 0.0847020000000001 2E-18 17.699 rs6126042 0.035366826 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS588106_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals T 0.084714 1E-20 20 rs6126042 0.03744748 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS759336_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 4E-19 18.398 rs6126042 N/A eosinophil count (EFO:0004842)
 PMID:30595370
Database
Acc Id
Source(s)
GWAS Catalog GCST90002381 GWAS Catalog

Note Type Note Reference