GWAS1146280_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1146280_H (uterine fibroid QTL GWAS1146280 (human)) Homo sapiens

Symbol: GWAS1146280_H
Name: uterine fibroid QTL GWAS1146280 (human)
RGD ID: 597050206
Trait: uterine fibroid
LOD Score: Not Available
P Value: 4.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38110,714,799 - 10,714,800RGD_MAPPER_PIPELINEGRCh38
GRCh37110,774,856 - 10,774,857RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146280_HHumanuterine fibroid  IAGPrs284247405850206 GWAS_CATALOGPMID:31488892

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146280_HHumanUterine leiomyoma  IAGPrs284247405850206 GWAS_CATALOGPMID:31488892
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1146280_HHumanuterine fibroid  IAGPrs284247405850206 GWAS_CATALOGPMID:31488892

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1606535CASZ1castor zinc finger 111063660410796646Human


Peak: (rs284247)
Human AssemblyChrPosition (strand)Source
GRCh38110,714,799 - 10,714,800RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597050307GWAS1146381_Huterine fibroid QTL GWAS1146381 (human)0.000003uterine fibroid11071479910714800Human
597050206GWAS1146280_Huterine fibroid QTL GWAS1146280 (human)0.000004uterine fibroid11071479910714800Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597309206GWAS1405280_Hvaginal microbiome measurement QTL GWAS1405280 (human)0.000006vaginal microbiome measurement11071479910714800Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1146280_H GCST009834 Uterine fibroids 5,236 Japanese ancestry cases, 39,556 Japanese ancestry controls ? NR 0.000004 5.398 rs284247 1.098901 uterine fibroid (EFO:0000731)
 PMID:31488892
GWAS1146381_H GCST009833 Uterine fibroids (MTAG) 5,236 Japanese ancestry cases, 39,556 Japanese ancestry controls ? NR 0.000003 5.523 rs284247 1.0309278 uterine fibroid (EFO:0000731)
 PMID:31488892
GWAS1405280_H GCST90026721 Vaginal microbiome MetaCyc pathway (COLANSYN-PWY|colanic acid building blocks biosynthesis) 315 Chinese ancestry individuals G NR 0.000006 5.222 rs284247 0.3376 vaginal microbiome measurement (EFO:0011013)
 PMID:34282934
Database
Acc Id
Source(s)
GWAS Catalog GCST009834 GWAS Catalog

Note Type Note Reference