GWAS1139089_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS1139089_H (schizophrenia QTL GWAS1139089 (human)) Homo sapiens

Symbol: GWAS1139089_H
Name: schizophrenia QTL GWAS1139089 (human)
RGD ID: 597043015
Trait: schizophrenia
LOD Score: Not Available
P Value: 5.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3818,435,530 - 8,435,531RGD_MAPPER_PIPELINEGRCh38
GRCh3718,495,590 - 8,495,591RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1139089_HHumanschizophrenia  IAGPrs172531405850206Based on the MONDO term ID from GWASGWAS_CATALOGPMID:31740837


#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1344336REREarginine-glutamic acid dipeptide repeats183524048817640Human


Peak: (rs172531)
Human AssemblyChrPosition (strand)Source
GRCh3818,435,530 - 8,435,531RGD_MAPPER_PIPELINE


1 to 10 of 11 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
597043015GWAS1139089_Hschizophrenia QTL GWAS1139089 (human)5e-12schizophrenia184355308435531Human
597073013GWAS1169087_Hschizophrenia QTL GWAS1169087 (human)5e-11schizophrenia184355308435531Human
597204508GWAS1300582_Hopen-angle glaucoma QTL GWAS1300582 (human)0.0000006open-angle glaucoma184355308435531Human
597213292GWAS1309366_Hschizophrenia QTL GWAS1309366 (human)1e-09schizophrenia184355308435531Human
597204498GWAS1300572_Hopen-angle glaucoma QTL GWAS1300572 (human)0.000005open-angle glaucoma184355308435531Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
597213732GWAS1309806_Hschizophrenia QTL GWAS1309806 (human)3e-08schizophrenia184355308435531Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human

1 to 10 of 11 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1139089_H GCST009337 Schizophrenia 22,778 East Asian ancestry cases, 35,362 East Asian ancestry controls, 33,640 European ancestry cases, 43,456 European ancestry controls ? NR 5E-12 11.302 rs172531 1.0746564 PMID:31740837
GWAS1169087_H GCST004946 Schizophrenia 7,699 Chinese ancestry cases, 35,476 European ancestry cases, 18,327 Chinese ancestry controls, 46,839 European ancestry controls G NR 5E-11 10.302 rs172531 1.0741138 PMID:28991256
GWAS1300572_H GCST90011768 Glaucoma (primary open-angle) 6,935 East Asian ancestry cases, 39,588 East Asian ancestry controls A NR 0.000005 5.302 rs172531 0.871709 open-angle glaucoma (EFO:0004190)
 PMID:33627673
GWAS1300582_H GCST90011770 Glaucoma (primary open-angle) 23,963 European ancestry cases, 306,942 European ancestry controls, 6,935 East Asian ancestry cases, 39,588 East Asian ancestry controls, 3,281 Sub-Saharan African ancestry cases, 2,791 Sub-Saharan African ancestry controls A NR 6E-7 6.222 rs172531 0.0379 open-angle glaucoma (EFO:0004190)
 PMID:33627673
GWAS1309366_H GCST007201 Schizophrenia 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls G NR 1E-9 9 rs172531 1.0683761 PMID:30285260
GWAS1309806_H GCST007201 Schizophrenia 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls G NR 3E-8 7.523 rs172531 1.0663254 PMID:30285260
Database
Acc Id
Source(s)
GWAS Catalog GCST009337 GWAS Catalog

Note Type Note Reference