GWAS1122427_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1122427_H (loneliness measurement QTL GWAS1122427 (human)) Homo sapiens

Symbol: GWAS1122427_H
Name: loneliness measurement QTL GWAS1122427 (human)
RGD ID: 597026353
Trait: emotion/affect behavior trait   (VT:0002572)    
Measurement Type: voluntary social interaction measurement   (CMO:0002676)    
LOD Score: Not Available
P Value: 3.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38611,959,603 - 11,959,604RGD_MAPPER_PIPELINEGRCh38
GRCh37611,959,836 - 11,959,837RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1122427_HHumanvoluntary social interaction measurement  IAGPrs10456089405850206 GWAS_CATALOGPMID:34054130

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1122427_HHumanemotion/affect behavior trait  IAGPrs10456089405850206 GWAS_CATALOGPMID:29970889

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1122427_HHumanloneliness measurement  IAGPrs10456089405850206 GWAS_CATALOGPMID:29970889
GWAS1122427_HHumansocial interaction measurement  IAGPrs10456089405850206 GWAS_CATALOGPMID:34054130

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
38660054LOC107986570uncharacterized LOC10798657061193403011961002Human


Peak: (rs10456089)
Human AssemblyChrPosition (strand)Source
GRCh38611,959,603 - 11,959,604RGD_MAPPER_PIPELINE


1 to 10 of 17 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2289408BW324_HBody weight QTL 324 (human)3.150.0001Body fat amount6120803913Human
1643418BW282_HBody Weight QTL 282 (human)2.070.001Body weight6119321359Human
597053589GWAS1149663_Hneuroticism measurement QTL GWAS1149663 (human)3e-10neuroticism measurement61195960311959604Human
597026353GWAS1122427_Hloneliness measurement QTL GWAS1122427 (human)3e-09emotion/affect behavior trait (VT:0002572)voluntary social interaction measurement (CMO:0002676)61195960311959604Human
597026480GWAS1122554_Hloneliness measurement QTL GWAS1122554 (human)9e-09emotion/affect behavior trait (VT:0002572)61195960311959604Human
1643377BW325_HBody weight QTL 325 (human)2.320.0005Body fat amount6691196032911960Human
1643569GLUCO21_HGlucose level QTL 21 (human)0.021Glucose levelnon-insulin-dependent6691196032911960Human
1298458BW9_HBody weight QTL 9 (human)2.70.0002Body fat amount6691196032911960Human
2289320BW390_HBody weight QTL 390 (human)2.13Body weightBMI6119321359Human
1358854MULTSCL4_HMultiple sclerosis susceptibility QTL 4 (human)Multiple sclerosis susceptibility6691196032911960Human

1 to 10 of 17 rows


Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1122427_H GCST006923 Loneliness 80,134 European ancestry cases, 364,890 European ancestry controls G 0.921 3E-9 8.523 rs10456089 0.0093 loneliness measurement (EFO:0007865)
 PMID:29970889
GWAS1122554_H GCST006924 Loneliness (MTAG) 487,647 European ancestry individuals G 0.920701 9E-9 8.046 rs10456089 0.02174949 loneliness measurement (EFO:0007865)
 PMID:29970889
GWAS1149663_H GCST007084 Neuroticism approximately 372,000 European ancestry individuals ? NR 3E-10 9.523 rs10456089 N/A neuroticism measurement (EFO:0007660)
 PMID:30595370
GWAS1168458_H GCST006940 Neurociticism 380,506 European ancestry individuals A 0.0758129 4E-9 8.398 rs10456089 5.89 neuroticism measurement (EFO:0007660)
 PMID:29500382
GWAS1343534_H GCST009463 Loneliness 511,280 European ancestry individuals ? NR 2E-8 7.699 rs10456089 0.04 loneliness measurement (EFO:0007865)
 PMID:31518406
None Available GCST012114 Sociability score 342,461 European ancestry individuals A NR 3E-9 8.523 rs10456089 0.02434 social interaction measurement (EFO:0009592)
 PMID:34054130
GWAS1347668_H GCST012111 Worry too long after an embarrassing experience 342,461 European ancestry individuals ? NR 9E-7 6.046 rs10456089 N/A worry measurement (EFO:0009589)
 PMID:34054130
None Available GCST012110 Loneliness 342,461 European ancestry individuals ? NR 2E-8 7.699 rs10456089 N/A loneliness measurement (EFO:0007865)
 PMID:34054130
Database
Acc Id
Source(s)
GWAS Catalog GCST006923 GWAS Catalog
  GCST012114 GWAS Catalog

Note Type Note Reference